Results 71 to 80 of about 43,844 (154)

Mammalian Epoxide Hydrolases

, 2018
Epoxide hydrolases (EHs) metabolize highly reactive epoxides with mutagenic and carcinogenic potential to the less reactive corresponding diols and are therefore traditionally viewed as detoxicating enzymes.
Arand, Michael; https://orcid.org/, M. Arand, Marowsky, Anne, A. Marowsky   +3 more
core   +1 more source

Regulation Roles of Juvenile Hormone Epoxide Hydrolase Gene 2 in the Female River Prawn Macrobrachium nipponense Reproductive Process

Current Issues in Molecular Biology
In this study, we investigated the regulatory roles of the juvenile hormone epoxide hydrolase (JHEH) gene in the reproductive process of female Macrobrachium nipponense. Its total cDNA length was 1848 bp, encoding for 460 amino acids.
Jisheng Wang, Mengying Zhang, Hongtuo Fu, Wenyi Zhang, Yiwei Xiong, Shubo Jin, Hui Qiao, Sufei Jiang   +7 more
doaj   +1 more source

Multienzyme Cascade Reactions: Compatibility, Cooperativity, and Control

Advanced Synthesis &Catalysis, Volume 368, Issue 21, 3 November 2026.
Multienzyme cascade reactions are sequences of telescoped biotransformations that avoid the isolation of intermediates and offer significant efficiency advantages over traditional multistep routes. This review article highlights recent examples of multienzyme cascades and explores how their success depends on the consideration of compatibility ...
Isabella E. E. Kroschel, Wolfgang Kroutil, Joerg H. Schrittwieser   +2 more
wiley   +1 more source

Cloning, characterization and heterologous expression of epoxide hydrolase-encoding cDNA sequences from yeasts belonging to the genera Rhodotorula and Rhodosporidium

, 2002
Epoxide hydrolase-encoding cDNA sequences were isolated from the basidiomycetous yeast species Rhodosporidium toruloides CBS 349, Rhodosporidium toruloides CBS 14 and Rhodotorula araucariae CBS 6031 in order to evaluate the molecular data and potential ...
Verdoes, J.C., Weijers, C.A.G.M., Ooyen, A.J.J., van, Visser, H.   +3 more
core   +1 more source

Enzymes from Extreme Environments and their Industrial Applications

Frontiers in Bioengineering and Biotechnology, 2015
This article will discuss the importance of specific extremophilic enzymes for applications in industrial biotechnology. It will specifically address those enzymes that have applications in the area of biocatalysis.
Jennifer Ann Littlechild
doaj   +1 more source

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

Chemistry – A European Journal, Volume 32, Issue 39, 22 October 2026.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

Multitarget Drug Design for Cardiovascular Disease: Bridging Chemistry and Medicine

ChemMedChem, Volume 21, Issue 19, 14 October 2026.
Many pathophysiological pathways associated with cardiovascular diseases involve multiple drug targets. This article reviews recent advances in the development of pharmacological compounds capable of simultaneously modulating multiple mechanisms. Multitarget drugs offer a promising therapeutic approach for complex cardiovascular disorders, including ...
Gyuzel Y. Mitronova, Vladimir N. Belov, Constanze Schmidt, Stephan E. Lehnart   +3 more
wiley   +1 more source

New High-Throughput Screening Assays for Biocatalysis

CHIMIA, 2001
High-throughput screening for catalysis is a critical technology in all experiments aimed at modifying or creating enzymes by directed evolution, as well as for biodiversity mining for new catalysts.
Jean-Louis Reymond
doaj   +2 more sources

Photobiocatalytic Linear Deracemization of β‐Hydroxynitriles

ChemSusChem, Volume 19, Issue 19, 14 October 2026.
Photosensitizers were screened for the oxidation of β‐hydroxynitriles under blue light irradiation, finding tetra‐n‐butyl decatungstate as the most suitable catalyst for accessing ketonitriles. Subsequently, bioreductions were carried out, leading to the identification of stereocomplementary alcohol dehydrogenases for the development of a linear ...
Sara Filgueira, Fernando López‐Gallego, Vicente Gotor‐Fernández   +2 more
wiley   +1 more source

Reorganization of Innate Immune Cell Lipid Profiles by Bioinspired Meroterpenoids to Limit Inflammation

Advanced Science, Volume 13, Issue 59, 23 October 2026.
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl, David Holubek, Klaus Speck, Raphael Wildermuth, Franz‐Lucas Haut, Stephan Permann, Immanuel Plangger, Christian Steinborn, Zhigang Rao, Danilo D'Avino, Ida Cerqua, Julia Stadler, Fiorentina Roviezzo, Peter Schlenke, Anita Siller, Harald Schennach, Solveigh C. Koeberle, Eva‐Maria Pferschy‐Wenzig, Antonietta Rossi, Thomas Magauer, Andreas Koeberle   +20 more
wiley   +1 more source