Results 51 to 60 of about 128,828 (279)
A single meal has the potential to alter brain oxylipin content. [PDF]
, 2020 Our objective was to determine whether consumption of a single meal has the potential to alter brain oxylipin content. We examined the cerebrum of mice fed a single high-fat/high-sucrose Western meal or a low-fat/low-sucrose control meal, as well as ...
Aung, HH +5 more
core +1 more source
Why Leave a Job Half Done? Recent Progress in Enzymatic Deracemizations [PDF]
, 2015 Financial support of this work by the Spanish MICINN (Projects CTQ2011-24237 and CTQ2013-44153) is gratefully ...
Díaz Rodríguez, Alba +2 more
core +2 more sources
Is Promiscuous CALB a Good Scaffold for Designing New Epoxidases?
Molecules, 2015 Candida Antarctica lipase B (CALB) is a well-known enzyme, especially because of its promiscuous activity. Due to its properties, CALB was widely used as a benchmark for designing new catalysts for important organic reactions.
Isabel Bordes +3 more
doaj +1 more source
Lipase catalysed kinetic resolution of racemic 1,2-diols containing a chiral quaternary center [PDF]
, 2018 Optically active 1,2-diols are valuable buildings blocks in organic synthesis. In the present paper, a set of racemic 1,2-diols with an ester functional group are prepared, starting from -ketoesters in a three-step procedure with moderate yields.
Gonzalo Calvo, Gonzalo de
core +2 more sources
Microsomal epoxide hydrolase polymorphisms
Molecular Medicine Reports, 2010 Microsomal epoxide hydrolase plays a dual role in the activation and detoxification of carcinogenic compounds. Two polymorphic sites have been described in exons 3 and 4 of the microsomal epoxide hydrolase gene that change tyrosine residue 113 to histidine (Tyr113His) and histidine 139 to arginine (His139Arg), respectively.
Pinarbasi, Hatice +2 more
openaire +5 more sources
Structural classification by the Lipase Engineering Database: a case study of Candida antarctica lipase A [PDF]
, 2010 Background The Lipase Engineering Database (LED) integrates information on sequence, structure and function of lipases, esterases and related proteins with the α/β hydrolase fold.
Michael Widmann +2 more
core +1 more source
Soluble Epoxide Hydrolase in Atherosclerosis [PDF]
Current Atherosclerosis Reports, 2010 Like many eicosanoids, epoxyeicosatrienoic acids (EETs) have multiple biological functions, including reduction of blood pressure, inflammation, and atherosclerosis in multiple species. Hydration of EETs by the soluble epoxide hydrolase (sEH) is the major route of their degradation to the less bioactive diols.
Wang, Yi-Xin Jim +3 more
openaire +4 more sources
Anti-tubercular activity of a natural stilbene and its synthetic derivatives
GMS Infectious Diseases, 2018 Objectives: Tuberculosis (TB) and multidrug- and extensively drug-resistant TB in particular are remaining a major global health challenge and efficient new drugs against TB are needed.
Reinheimer, Claudia +5 more
doaj +1 more source
Microorganisms, 2021 Trichoderma hamatum FBL 587 isolated from DDT-contaminated agricultural soils stands out as a remarkable strain with DDT-resistance and the ability to enhance DDT degradation process in soil.
Domenico Davolos +8 more
doaj +1 more source
Structural characterization of a hypothetical protein: a potential agent involved in trimethylamine metabolism in Catenulispora acidiphila [PDF]
, 2014 Catenulispora acidiphila is a newly identified lineage of actinomycetes that produces antimicrobial activities and represents a promising source of novel antibiotics and secondary metabolites. Among the discovered protein coding genes, 68 % were assigned
Chi-Hao Luan +6 more
core +1 more source