Results 51 to 60 of about 43,844 (154)
Sequence and structure of epoxide hydrolases : a systematic analysis [PDF]
, 2015 Epoxide hydrolases (EC 3.3.2.3) are ubiquitous enzymes which catalyze the hydrolysis of epoxides to the corresponding vicinal diols. Over 100 epoxide hydrolases (EH) have been identified or predicted, 3 structures are available.
Barth, Sandra +3 more
core +1 more source
Journal of Lipid Research, 2019 A chiral lipidomics approach was established for comprehensive profiling of regio- and stereoisomeric monoepoxy and monohydroxy metabolites of long-chain PUFAs as generated enzymatically by cytochromes P450 (CYPs), lipoxygenases (LOXs), and ...
Maximilian Blum +4 more
doaj +1 more source
A first insight into Pycnoporus sanguineus BAFC 2126 transcriptome. [PDF]
PLoS ONE, 2013 Fungi of the genus Pycnoporus are white-rot basidiomycetes widely studied because of their ability to synthesize high added-value compounds and enzymes of industrial interest.
Cristian O Rohr +3 more
doaj +1 more source
Synthesis of Microbial‐Derived Octadecanoids
Lipids, EarlyView.C18‐carbon containing dietary polyunsaturated fatty acids (e.g., linoleic acid, α‐linolenic acid, and γ‐linolenic acid) are metabolized by bacteria in the gut into oxygenated lipid mediators termed octadecanoids. To study the biological function of these compounds, we report here the chemical synthesis of multiple octadecanoids.
Johanna Revol‐Cavalier +6 more
wiley +1 more source
Mammalian epoxide hydrolases in xenobiotic metabolism and signalling [PDF]
, 2018 Epoxide hydrolases catalyse the hydrolysis of electrophilic—and therefore potentially genotoxic—epoxides to the corresponding less reactive vicinal diols, which explains the classification of epoxide hydrolases as typical detoxifying enzymes.
Decker, Martina +2 more
core
Mycobacterial Epoxide Hydrolase EphD Is Inhibited by Urea and Thiourea Derivatives
, 2021 The genome of the human intracellular pathogen Mycobacterium tuberculosis encodes an unusually large number of epoxide hydrolases, which are thought to be involved in lipid metabolism and detoxification reactions needed to endure the hostile environment ...
Martin Kopál +3 more
core +1 more source
Bioresources and Bioprocessing, 2018 Background Deep eutectic solvents have attracted considerable attention in numerous fields. There is little information on mung bean epoxide hydrolase-catalyzed epoxides in deep eutectic solvent-containing system.
Fei Peng +4 more
doaj +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
The telltale structures of epoxide hydrolases
, 2003 Traditionally, epoxide hydrolases (EH) have been regarded as xenobiotic-metabolizing enzymes implicated in the detoxification of foreign compounds. They are known to play a key role in the control of potentially genotoxic epoxides that arise during ...
Oesch, Franz +9 more
core +2 more sources
Exploring Solanum tuberosum Epoxide Hydrolase Internal Architecture by Water Molecules Tracking
Biomolecules, 2018 Several different approaches are used to describe the role of protein compartments and residues in catalysis and to identify key residues suitable for the modification of the activity or selectivity of the desired enzyme.
Karolina Mitusińska +4 more
doaj +1 more source