Results 191 to 200 of about 15,949 (256)

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

An Interpretable Machine‐Learning Framework for Multi‐Endpoint Drug‐Induced Liver Injury Classification: Evaluating the Contribution of Molecular Structure

open access: yesAdvanced Computing, Volume 1, Issue 1, December 2026.
Molecular structure provides a complementary perspective on drug‐induced liver injury. Integrating 801 drugs across five DILI endpoints, our interpretable AI framework reveals endpoint‐dependent structural contributions and links predictive classification with molecular‐level interpretation, highlighting the complex interplay between clinical ...
Priya Kumari, Kunal Roy, Madhulika Gupta
wiley   +1 more source

The Impact of Genetic Polymorphisms on Genotoxicity (DNA Damage) Among Children Exposed to Environmental Mutagens: A Systematic Review

open access: yesJournal of Applied Toxicology, Volume 46, Issue 12, Page 4396-4408, December 2026.
ABSTRACT Children, as a particularly vulnerable group, are more susceptible to these mutagens due to their developing immune systems, higher physiological vulnerability, and increased exposure through behaviors like outdoor play and hand‐to‐mouth activities. This review aims to investigate the relationship between these environmental exposures, genetic
Thiago Guedes Pinto   +7 more
wiley   +1 more source

Pangenomic framework for globe artichoke supports SNP‐based varietal fingerprinting

open access: yesThe Plant Genome, Volume 19, Issue 4, December 2026.
Abstract Globe artichoke (Cynara cardunculus var. scolymus L.) comprises a broad range of local ecotypes and varietal groups whose genetic diversity has been investigated through different molecular markers. However, recent advances in next‐generation sequencing and pangenomic approaches provide new opportunities to capture genome‐wide variation at ...
Ezio Portis   +7 more
wiley   +1 more source
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Epoxide Electroreduction

Journal of the American Chemical Society, 2021
Selective hydrogenation of epoxides would be a direct and powerful approach for alcohol synthesis, but it has proven to be elusive. Here, electrochemically epoxide hydrogenation using electrons and protons as reductants is reported. A wide range of primary, secondary, and tertiary alcohols can be achieved through selective Markovnikov or anti ...
Cheng Huang   +5 more
openaire   +2 more sources

Graphite Epoxide

Journal of the American Chemical Society, 2008
Oxidation of graphite may be carried out by reaction with meta-chloroperoxybenzoic acid to yield graphite epoxide. Scanning tunneling microscopy (STM) showed that the functionalization occurs at the edges rather than on the basal plane of the graphite.
Jayanta, Chattopadhyay   +8 more
openaire   +2 more sources

Organocatalytic Asymmetric Hydrolysis of Epoxides

open access: yesAngewandte Chemie - International Edition, 2014
The hydrolytic ring opening of epoxides is an important biosynthetic transformation and is also applied industrially. We report the first organocatalytic variant of this reaction, exploiting our recently discovered activation of carboxylic acids with ...
Sébastien Prévost, Benjamin List
exaly   +2 more sources

Epoxidation of alkenes

ChemInform, 1991
Publisher Summary The method for asymmetric epoxidation of alicyclic alcohols is known as Sharpless. The success of this method initiated much research into other techniques of asymmetric oxidation of alkenes in general and this chapter considers the progress in the area for the last six years.
openaire   +1 more source

Epoxidations: Titanium‐Catalyzed Epoxidation

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +1 more source

Ceramide-epoxides

Chemistry and Physics of Lipids, 2001
Previously unknown 4,5-epoxy-N-acetyl-sphingosine (1) was synthesized by epoxidation of N-acetyl-sphingosine with 1,1-dimethyldioxirane. A by-product generated by HPLC purification is the tetrahydrofuryl derivative of acetamide (2). Mainly allylic oxidation was observed when natural ceramides were reacted with dimethyldioxirane.
A, Möllenberg, G, Spiteller
openaire   +2 more sources

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