Rearrangement of Protected Epoxy-Alcohols into Tetrahydrofuran Derivatives: The Protecting Group Matters! [PDF]
TetrahedronNirpal AK, Sathyamoorthi S.
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MedComm – Oncology, Volume 5, Issue 3, September 2026.Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K +5 more
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A reflection on 'Bimetallic mechanism operating in the copolymerization of propylene oxide with carbon dioxide catalyzed by cobalt-salen complexes'. [PDF]
Chem SciNakano K, Nozaki K.
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Rapid Communications in Mass Spectrometry, Volume 40, Issue 16, 30 August 2026.ABSTRACT Rationale Cannabinoids comprise a chemically diverse group of meroterpenoids whose extensive isomerism, variable side‐chain length, and frequent oxidative or rearranged derivatives lead to strongly overlapping yet characteristic MS/MS fragmentation patterns. In untargeted LC–MS/MS datasets, this combination of structural diversity and spectral
Julia Maia Galvão de Queiroz +4 more
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Thermally driven conformational tuning of pyridine bis-salicylaldimine for efficient CO<sub>2</sub> activation and cyclic carbonate formation under mild conditions. [PDF]
Chem SciMishra V +5 more
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Oxygen Attachment Dissociation of Protonated Reserpine and Its Analogs
Rapid Communications in Mass Spectrometry, Volume 40, Issue 14, 30 July 2026.ABSTRACT Rationale Carbon–carbon double bonds are ubiquitous structural motifs in natural products and pose a key challenge in locating their presence in analytes via MS‐based methods. Here, we use the alkaloid reserpine as a model system to examine whether OAD reactions can locate quaternary double bonds embedded in fused multicyclic structures ...
Jack G. Li +5 more
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Epoxide Hydrolase Family: Biological Functions, Disease Mechanisms, and Emerging Therapeutic Strategies. [PDF]
Biology (Basel)Tan Y +6 more
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Mutasynthesis and Antibiotic Activity of Mupirocin Analogues
ChemBioChem, Volume 27, Issue 13, 14 July 2026.A mutasynthetic strategy was developed to prepare pseudomonic acid analogues, and their antimicrobial activities were evaluated against five bacterial strains. Feeding studies with mutant strains of Pseudomonas fluorescens revealed that C7‐desepoxy‐PA‐B was metabolised to C7‐PA‐C with loss of the 8‐hydroxyl group, but no fatty acid chain extension ...
Sarah M. Husain +11 more
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Understanding low-pressure CO<sub>2</sub> insertion chemistry in epoxide-CO<sub>2</sub> copolymerization catalysis. [PDF]
Nat ChemThorogood R +3 more
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Synthetic Ligands of Myeloid C‐Type Lectin Receptors
ChemBioChem, Volume 27, Issue 13, 14 July 2026.Binding of ligands to C‐type lectin receptors (CLRs) on myeloid cells can lead to an array of cellular responses. Exploitation of these receptors for therapeutic purposes requires high‐affinity ligands. This review surveys the diversity of synthetic ligands of myeloid CLRs in the context of binding, signaling, and downstream effects, as well as ...
James Suri, Bernd Lepenies
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