A randomized, double-blinded trial comparing the effectiveness of tranexamic acid and epsilon-aminocaproic acid in reducing bleeding and transfusion in cardiac surgery [PDF]
Annals of Cardiac Anaesthesia, 2019 Objectives: To compare the effectiveness of epsilon aminocaproic acid (EACA) to tranexamic acid (TA) in reducing blood loss and transfusion requirements in patients undergone cardiac surgery under cardiopulmonary bypass.
Jonathan Leff +5 more
doaj +6 more sources
Combination of Intravenous and Intra‐Articular Application of Tranexamic Acid and Epsilon‐Aminocaproic Acid in Primary Total Knee Arthroplasty: A Prospective Randomized Controlled Trial [PDF]
Orthopaedic Surgery, 2023 Objective There were limited randomized controlled trials (RCTs) of epsilon‐aminocaproic acid (EACA) versus tranexamic acid (TXA) in total knee arthroplasty (TKA).
Che Zheng +6 more
doaj +3 more sources
The Optimal Dose, Efficacy and Safety of Tranexamic Acid and Epsilon‐Aminocaproic Acid to Reduce Bleeding in TKA: A Systematic Review and Bayesian Network Meta‐analysis [PDF]
Orthopaedic Surgery, 2023 Objective The optimal dose and efficacy of tranexamic acid (TXA) and epsilon‐aminocaproic acid (EACA) in total knee arthroplasty (TKA) were under controversial, and we aimed to make comparisons between different doses of TXA and EACA in intravenous (IV ...
Che Zheng +7 more
doaj +3 more sources
INTRAARTICULAR EPSILON AMINOCAPROIC ACID VERSUS TRANEXAMIC ACID IN TOTAL KNEE ARTHROPLASTY [PDF]
Acta Ortopédica Brasileira, 2021 Objective: To examine and compare the clinical efficacy of intraarticular epsilon aminocaproic acid (EACA) and tranexamic acid (TXA) in total knee arthroplasty (TKA).
JOAO PAULO FERNANDES GUERREIRO +5 more
doaj +3 more sources
A New Insight on the Radioprotective Potential of Epsilon-Aminocaproic Acid [PDF]
Medicina, 2020 Background and objectives: The aim of the study was to scrutinize the ability of epsilon-aminocaproic acid (EACA) to prevent radiation-induced damage to human cells.
Timur Saliev +8 more
doaj +3 more sources
Comparison of intraoperative tranexamic acid and epsilon-aminocaproic acid in cardiopulmonary bypass patientsCentral MessagePerspective [PDF]
JTCVS Open, 2020 Objective: To compare tranexamic acid (TXA) and epsilon-aminocaproic acid (EACA) in patients undergoing cardiac surgery with cardiopulmonary bypass. Methods: Over a consecutive 2-year period, 824 adult cardiac surgery patients who received TXA during an ...
Mark Broadwin, MS +6 more
doaj +3 more sources
Systematic review and meta-analysis of tranexamic acid and epsilon aminocaproic acid in pediatric heart surgery [PDF]
Polish Journal of Thoracic and Cardiovascular SurgeryIn pediatric cardiac surgery, the use of antifibrinolytic agents, specifically tranexamic acid (TXA) and epsilon-ami - nocaproic acid (EACA)
Lukasz Szarpak +3 more
doaj +3 more sources
Epsilon-aminocaproic acid versus tranexamic acid in total knee arthroplasty: a meta-analysis study [PDF]
Journal of Orthopaedics and Traumatology, 2019 Introduction Total knee arthroplasty (TKA) surgery can be associated with significant blood loss. Among the problems associated with such blood loss is the need for transfusions of banked blood [1].
Osman Riaz +7 more
doaj +3 more sources
High Dose, Prolonged Epsilon Aminocaproic Acid Infusion, and Recombinant Factor VII for Massive Postoperative Retroperitoneal Hemorrhage following Splenectomy [PDF]
Case Reports in Anesthesiology, 2016 The antifibrinolytic agent ε-aminocaproic acid is used to decrease procedural blood loss in a variety of high risk surgeries. The utility of recombinant factor VII administration in massive hemorrhage has also been reported in a variety of settings ...
Alex T. Lee +3 more
doaj +3 more sources
Commentary: Epsilon-aminocaproic acid versus tranexamic acid, the David and Goliath of antifibrinolyticsCentral Message [PDF]
JTCVS Open, 2020 David Faraoni, MD, PhD, FAHA
doaj +3 more sources