Results 11 to 20 of about 10,578 (221)

Comparison of efficacy between tranexamic acid and epsilon-aminocaproic acid for total knee arthroplasty: A meta-analysis of randomized controlled trials. [PDF]

Medicine (Baltimore), 2023
Background: Tranexamic acid (TXA) and epsilon-aminocaproic acid (EACA) have been demonstrated to reduce blood loss following total knee arthroplasty (TKA). This meta-analysis aimed to compare the efficacy and safety of TXA and EACA in reducing blood loss
Li J, Guo Y, Li M.
europepmc   +2 more sources

Tranexamic Acid versus Epsilon-Aminocaproic Acid in Total Knee Arthroplasty: A Meta-Analysis.

J Healthc Eng, 2021
Objective At present, the effect of tranexamic acid (TXA) and epsilon-aminocaproic acid (EACA) on total knee arthroplasty (TKA) remains controversial. Therefore, the aim of this meta-analysis is to compare the differences between the effects of TXA and ...
Li Z, Sun X, Li W, Zhang M.
europepmc   +2 more sources

Comparison between epsilon-aminocaproic acid and tranexamic acid for total hip and knee arthroplasty: A meta-analysis

Journal of Orthopaedic Surgery, 2020
Background: The aim was to compare the efficacy and safety of epsilon-aminocaproic acid (EACA) and tranexamic acid (TXA) in total hip arthroplasty (THA) and total knee arthroplasty (TKA).
Wen-bin Liu, Gui-Shi Li, Peng Shen, Fu-jiang Zhang   +3 more
doaj   +2 more sources

Efficacy and safety of epsilon-aminohexanoic acid and tranexamic acid during posterior interbody fusion surgery [PDF]

Frontiers in Surgery
BackgroundTranexamic acid (TXA) is a proven effective and favored antifibrinolytic hemostatic drug, while epsilon-aminocaproic acid (EACA) has only recently been applied in the field of orthopedics.
Dilixiati Ainiwaer, Ayinuer Tuersun, Jiang Li, Xiaomei Li   +3 more
doaj   +2 more sources

Alkaline phosphatase–streptavidin conjugate (APSA) enzyme and binding activity over time and storage conditions [PDF]

Biochemistry and Biophysics Reports
Alkaline phosphatase (AP) linked to streptavidin (SA) in the form of the APSA enzyme conjugate is required for diagnostic screening for a variety of clinical conditions world wide.
Nan Cheng, Lloyd Johnson, Jaimie Dufresne, Sina Mazinani, John G. Marshall   +4 more
doaj   +2 more sources

A prospective, randomized, double-blinded single-site control study comparing blood loss prevention of tranexamic acid (TXA) to epsilon aminocaproic acid (EACA) for corrective spinal surgery [PDF]

BMC Surgery, 2010
Background Multilevel spinal fusion surgery has typically been associated with significant blood loss. To limit both the need for transfusions and co-morbidities associated with blood loss, the use of anti-fibrinolytic agents has been proposed.
Vaz Kenneth M, Errico Thomas J, Verma Kushagra, Lonner Baron S   +3 more
doaj   +2 more sources

Are antifibrinolytic drugs equivalent in reducing blood loss and transfusion in cardiac surgery? A meta-analysis of randomized head-to-head trials [PDF]

BMC Cardiovascular Disorders, 2005
Background Aprotinin has been shown to be effective in reducing peri-operative blood loss and the need for re-operation due to continued bleeding in cardiac surgery.
Stokes Barrie J, Moxey Annette J, Carless Paul A, Henry David A   +3 more
doaj   +5 more sources

Population pharmacokinetics of epsilon-aminocaproic acid in infants undergoing craniofacial reconstruction surgery. [PDF]

Br J Anaesth, 2013
Stricker PA, Zuppa AF, Fiadjoe JE, Maxwell LG, Sussman EM, Pruitt EY, Goebel TK, Gastonguay MR, Taylor JA, Bartlett SP, Schreiner MS.   +10 more
europepmc   +2 more sources

Epsilon aminocaproic acid is associated with acute kidney injury after life‐threatening hemorrhage in children

Transfusion, 2023
Antifibrinolytic medications have been associated with reduced mortality in pediatric hemorrhage but may contribute to adverse events such as acute kidney injury (AKI).
Julia H Kolodziej, Christine M. Leeper, Julie C. Leonard, C. Josephson, M. Zenati, P. Spinella   +5 more
semanticscholar   +1 more source

Epsilon Aminocaproic Acid’s Safety and Efficacy in Pediatric Surgeries Including Craniosynostosis Repair: A Review of the Literature

Cureus, 2022
Craniosynostosis, the premature fusion of skull sutures in children, requires surgical correction. This procedure routinely requires allogeneic blood transfusions, which are associated with multiple risks of their own.
A. Bolufer, T. Iwai, C. Baughn, A. Clark, G. Olavarria   +4 more
semanticscholar   +1 more source