Results 41 to 50 of about 1,399 (158)

Group B Streptococcus hijacks the host plasminogen system to promote brain endothelial cell invasion. [PDF]

PLoS ONE, 2013
Group B Streptococcus (GBS) is the leading cause of meningitis in neonates. We have previously shown that plasminogen, once recruited to the GBS cell surface and converted into plasmin by host-derived activators, leads to an enhancement of bacterial ...
Vanessa Magalhães, Elva Bonifácio Andrade, Joana Alves, Adilia Ribeiro, Kwang Sik Kim, Margarida Lima, Patrick Trieu-Cuot, Paula Ferreira   +7 more
doaj   +1 more source

Viscoelastic Testing for Coagulation Management in Vascular Surgery—A Narrative Review

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Viscoelastic testing (VET) has been increasingly used in cardiac, trauma, and hepatic surgery where it helps tackle the development of complex coagulopathies. Despite this, data on using VETs in vascular surgery remains limited to small and non‐randomised control studies. Although the improvement in vascular techniques has decreased
Alexandru Munteanu, Elena Bax
wiley   +1 more source

Massive Bleeding as the First Clinical Manifestation of Metastatic Prostate Cancer due to Disseminated Intravascular Coagulation with Enhanced Fibrinolysis

Case Reports in Hematology, 2016
Disseminated intravascular coagulation (DIC) is the most frequent coagulation disorder associated with metastatic prostate adenocarcinoma. However, DIC with enhanced fibrinolysis as an initial presentation of prostate cancer is extremely rare.
Mónica Palma Anselmo, Gustavo Nobre de Jesus, João Madeira Lopes, Rui M. M. Victorino, João Meneses Santos   +4 more
doaj   +1 more source

A prospective, randomized, double-blinded single-site control study comparing blood loss prevention of tranexamic acid (TXA) to epsilon aminocaproic acid (EACA) for corrective spinal surgery

BMC Surgery, 2010
Background Multilevel spinal fusion surgery has typically been associated with significant blood loss. To limit both the need for transfusions and co-morbidities associated with blood loss, the use of anti-fibrinolytic agents has been proposed.
Vaz Kenneth M, Errico Thomas J, Verma Kushagra, Lonner Baron S   +3 more
doaj   +1 more source

Diffusion of Epsilon Aminocaproic Acid to the Joints

Experimental Biology and Medicine, 1970
SummaryThe concentration of E-ACA in the joint fluid and joint capsule was measured at different intervals after iv injection of the substance in a dose of 0.1 g/kg body weight in 16 patients undergoing operation because of a ruptured meniscus of the knee joint. It was found that E-ACA diffuses to both of the above-mentioned tissues and that some E-ACA
openaire   +2 more sources

Recent Developments in Capillary and Microchip Electroseparations of Peptides (2023–mid 2025)

ELECTROPHORESIS, Volume 47, Issue 1, Page 106-136, January 2026.
ABSTRACT This review presents a comprehensive overview of the developments and applications of high‐performance capillary and microchip electromigration methods (zone electrophoresis in a free solution or in sieving media, isotachophoresis, isoelectric focusing, affinity electrophoresis, electrokinetic chromatography, and electrochromatography) for ...
Václav Kašička
wiley   +1 more source

A Case Report on the Surgical Extraction of a Third Molar in a Patient with Bernard–Soulier Syndrome, an Uncommon Disease

Indian Journal of Dental Sciences
We present a case of a patient with Bernard–Soulier syndrome (BSS) who had his impacted third mandibular molar surgically extracted. An uncommon congenital bleeding condition called BSS is inherited in an autosomal recessive fashion.
Ashish Kamboj, Chandan Mishra, Paras Angrish, S.S Chopra, Sunil Kumar Singh   +4 more
doaj   +1 more source

A study of the interaction between Helicobacter pylori and components of the human fibrinolytic system

Brazilian Journal of Medical and Biological Research, 2000
The interaction of plasminogen, tissue plasminogen activator (t-PA) and urokinase with a clinical strain of Helicobacter pylori was studied. Plasminogen bound to the surface of H. pylori cells in a concentration-dependent manner and could be activated to
A. Yarzábal, L. Avilán, K. Hoelzl, M. de Muñoz, J. Puig, I. Kansau   +5 more
doaj   +1 more source

Elamipretide Improves Mitochondrial Function in Mitochondrial Trifunctional Protein‐Deficient Mice and Human Fibroblasts

Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT Mitochondrial trifunctional protein (TFP) deficiency is an inherited disorder of long‐chain fatty acid β‐oxidation (FAO). TFP is a heteromeric enzyme composed of two α and two β‐subunits. Despite early detection and dietary treatment, TFP deficiency patients often develop hypoglycemia, rhabdomyolysis, cardiomyopathy, and peripheral neuropathy.
Eduardo Vieira Neto, Meicheng Wang, Austin J. Szuminsky, Lethicia Ferraro, Shakuntala Basu, Xuejun Zhao, Anuradha Karunanidhi, Yudong Wang, Jerry Vockley   +8 more
wiley   +1 more source

Effects of epsilon-aminocaproic acid on fertility in the rabbit [PDF]

Reproduction, 1978
Summary. Administration of epsilon-aminocaproic acid, a fibrinolytic inhibitor, either orally or from an impregnated IUD, had no effect on numbers of implanted embryos, their viability, or their diameters at Day 10 of pregnancy.
A T, Andrade, S T, Shaw, M O, Guerra, D E, Aaronson   +3 more
openaire   +2 more sources