Results 31 to 40 of about 1,675 (190)

Reduction of bleeding after heart operations through the prophylactic use of epsilon-aminocaproic acid

, 1996
Excessive postoperative bleeding after heart operations continues to be a source of morbidity. This prospective double-blind study evaluated epsilon-aminocaproic acid as an agent to reduce postoperative bleeding and investigated its mode of action.
Vander Salm, Thomas J., Okike, Okike N., Leone, Lisa, Lancey, Robert A., Stahl, Russell F., Li, Jian-Ming, Pezzella, A.Thomas, Michelson, Alan D., Valeri, C.Robert, Kaur, Shubjeet   +9 more
core   +1 more source

Antifibrinolytic Activity During Administration of Epsilon-Aminocaproic Acid

, 1971
Utilizing an in vitro method for activated and nonactivated whole blood clotlysis determinations, the antifibrinolytic effect of epsilon-aminocaproic acid therapy was evaluated. Initially, the induced antifibrinolytic activity diminished within two hours
DONALD W. NIBBELINK
core   +1 more source

Red urine, updated for the nephrologist: a case report

BMC Nephrology, 2018
Background Sickle cell trait is not completely benign, and some renal complications can occur. The baseline rate of admission for gross hematuria in normal males carrying the sickle cell trait is 2%.
Alexandre Le Joncour, Laurent Mesnard, Alexandre Hertig, Thomas Robert   +3 more
doaj   +1 more source

Aprotinin and epsilon aminocaproic acid are effective in reducing blood loss after primary total hip arthroplasty – a prospective randomized double-blind placebo-controlled study

, 2005
Summary. A prospective randomized double-blind placebo-controlled study was undertaken to determine the efficacy and mechanism of action of two antifibrinolytic drugs aprotinin and epsilon aminocaproic acid (EACA) in reducing blood loss in primary ...
Crawford, Scott W., Crawford, Ross W., Hatcher, Stephen, Whitehouse, Sarah L., Ray, Michael   +4 more
core   +1 more source

Perioperative Outcomes in Factor XI Deficiency: A Systematic Review

Haemophilia, EarlyView.
ABSTRACT Background Congenital factor XI (FXI) deficiency has a variable bleeding phenotype, and FXI activity alone does not predict perioperative bleeding. Management practices remain heterogeneous, and available evidence derives from case reports, small case series, and retrospective cohorts.
Zainab Al‐Housni, Raeesah Mohammed, Silvio Ligia, Jim Douketis, Chatree Chai‐Adisaksopha, Alfonso Iorio, Davide Matino   +6 more
wiley   +1 more source

Co-administration of Aprotinin and Epsilon–Aminocaproic Acid During Cardiopulmonary Bypass in a Swine Model

, 2023
Despite the beneficial effects of pharmacological interventions to prevent bleeding and to reduce the need for autogeneic blood, there are concerns that these agents induce a prothrombotic state.
See N. Vang, Thomas W. Viessman, Eric D. Rauch, Tianyu Yang, Alfred H. Stammers, Nancy L. Bruda, Brian L. Mejak   +6 more
core   +1 more source

Uso tópico de agente antifibrinolítico na redução do sangramento após revascularização cirúrgica do miocárdio Topical use of antifibrinolytic agent to reduce postoperative bleeding after coronary artery bypass surgery

Brazilian Journal of Cardiovascular Surgery, 2009
OBJETIVO: Verificar o efeito do uso tópico do ácido epsilon-aminocapróico (AEAC), aplicado na cavidade pericárdica, na redução do sangramento e necessidade de transfusão sanguínea no pós-operatório de revascularização cirúrgica do miocárdio.
João Roberto Breda, Danilo Bortoloto Gurian, Ana Silvia Castaldi Ragognetti Breda, Adriano Meneghine, Andréa Cristina de Oliveira Freitas, Leandro Mattos Luongo, Luiz Carlos de Abreu, Adilson Casemiro Pires   +7 more
doaj   +1 more source

Efficacy and safety of using aminocaproic acid and tranexamic acid during the perioperative period for treating trochanteric fractures in elderly femurs

BMC Musculoskeletal Disorders, 2023
Background Tranexamic acid (TXA) has long been the antifibrinolytic hemostatic drug of choice for orthopedic surgery. In recent years, the hemostatic effect of epsilon aminocaproic acid (EACA) has gradually been recognized by orthopedic surgeons and has ...
Alimujiang Yusufu, Abuduwupuer Haibier, Zheng Ren, Qi Qin, Ziyi Zhang, Yuan Zhou, Jian Ran   +6 more
doaj   +1 more source

Removal of Photosystem I Subunit PsaE Leads to Photosynthetic Hydrogen Production in a Cyanobacterial PsaF‐HoxYH Fusion Strain

Plant, Cell &Environment, EarlyView.
ABSTRACT Photosynthetic hydrogen (photoH2) production is a promising approach for the utilisation of solar energy. Fusion of a hydrogenase (H2ase) to photosystem I (PSI) provides a direct light‐driven route for photoH2 generation. We established the lateral transmembrane subunit PsaF of PSI as a new fusion partner for the NiFe‐hydrogenase (HoxYH) in ...
Florian Paul, Nadine Strabel, Marko Boehm, Jens Appel, Kirstin Gutekunst   +4 more
wiley   +1 more source

Hydrogel Adhesives for Gastrointestinal Perforation: Design Principles and Applications

Exploration, Volume 6, Issue 3, June 2026.
There are few reviews on hydrogel adhesives that comprehensively highlight the design principles, factors affecting adhesion, and applications for gastrointestinal (GI) perforation repair. This review outlines the mainstream design approaches of hydrogel adhesives via covalent and noncovalent molecular interactions, illustrating the underlying adhesive
Yudi Pang, Shuai Tian, Qinyu Han, Yulin Deng, Jiatao Zhang, Enqiang Linghu, Qianqian Chen, Zhimin Wang   +7 more
wiley   +1 more source