Epsilon-aminocaproic acid versus tranexamic acid in total knee arthroplasty: a meta-analysis study [PDF]
Journal of Orthopaedics and Traumatology, 2019 Introduction Total knee arthroplasty (TKA) surgery can be associated with significant blood loss. Among the problems associated with such blood loss is the need for transfusions of banked blood [1].
Osman Riaz +7 more
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A randomized, double-blinded trial comparing the effectiveness of tranexamic acid and epsilon-aminocaproic acid in reducing bleeding and transfusion in cardiac surgery [PDF]
Annals of Cardiac Anaesthesia, 2019 Objectives: To compare the effectiveness of epsilon aminocaproic acid (EACA) to tranexamic acid (TA) in reducing blood loss and transfusion requirements in patients undergone cardiac surgery under cardiopulmonary bypass.
Jonathan Leff +5 more
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Systematic review and meta-analysis of tranexamic acid and epsilon aminocaproic acid in pediatric heart surgery [PDF]
Polish Journal of Thoracic and Cardiovascular SurgeryLukasz Szarpak +3 more
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Comparative Analysis of Topical Versus Intravenous Administration of Epsilon-Aminocaproic Acid on Blood Management in Total Knee Arthroplasty. [PDF]
Kans J Med, 2022 Introduction. Although the use of antifibrinolytics to reduce perioperative blood loss during total knee arthroplasty (TKA) has shown unequivocal benefit in regard to blood conservation, the best route of administration remains in question. We tested the
Lancaster BL +6 more
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Revista Cubana de Anestesiología y Reanimación, 2016 Introduction: To reduce intraoperative blood loss and the use of transfusion requirements, antifibrinolytic agents that repermeabilize a bleeding vessel are used.
Zaily Fuentes Díaz +2 more
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High Dose, Prolonged Epsilon Aminocaproic Acid Infusion, and Recombinant Factor VII for Massive Postoperative Retroperitoneal Hemorrhage following Splenectomy [PDF]
Case Reports in Anesthesiology, 2016 The antifibrinolytic agent ε-aminocaproic acid is used to decrease procedural blood loss in a variety of high risk surgeries. The utility of recombinant factor VII administration in massive hemorrhage has also been reported in a variety of settings ...
Alex T. Lee +3 more
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Efficacy and safety of epsilon-aminohexanoic acid and tranexamic acid during posterior interbody fusion surgery [PDF]
Frontiers in SurgeryBackgroundTranexamic acid (TXA) is a proven effective and favored antifibrinolytic hemostatic drug, while epsilon-aminocaproic acid (EACA) has only recently been applied in the field of orthopedics.
Dilixiati Ainiwaer +3 more
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BMC Surgery, 2010 Background Multilevel spinal fusion surgery has typically been associated with significant blood loss. To limit both the need for transfusions and co-morbidities associated with blood loss, the use of anti-fibrinolytic agents has been proposed.
Vaz Kenneth M +3 more
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Commentary: Epsilon-aminocaproic acid versus tranexamic acid, the David and Goliath of antifibrinolyticsCentral Message [PDF]
JTCVS Open, 2020 David Faraoni, MD, PhD, FAHA
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Dental Management of Glanzmann's Thrombasthenia in a 4‐Year‐Old Child With Rampant Caries: A Case Report and Literature Review [PDF]
Clinical Case Reports, Volume 13, Issue 12, December 2025.ABSTRACT Glanzmann's Thrombasthenia (GT) is a rare congenital bleeding disorder in children, caused by the absence or dysfunction of glycoprotein (GP) IIb/IIIa, a receptor located on the platelet membrane. Proper oral health and regular dental appointments are crucial for these patients. However, maintaining good oral hygiene is challenging among them.
Bahareh Nazemisalman +3 more
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