Results 91 to 100 of about 396,299 (201)

Clostridium perfringens epsilon toxin inhibits the gastrointestinal transit in mice

Research in Veterinary Science, 2010
Epsilon toxin produced by Clostridium perfringens type B and D is a potent toxin that is responsible for a highly fatal enterotoxemia in sheep and goats. In vitro, epsilon toxin produces contraction of the rat ileum as the result of an indirect action, presumably mediated through the autonomic nervous system.
Losada Eaton, D. M., Fernandez Miyakawa, Mariano Enrique   +1 more
openaire   +3 more sources

Detection of Clostridium perfringens alpha toxin gene in lambs by loop mediated isothermal amplification [PDF]

Veterinary World, 2016
Aim: The loop mediated isothermal amplification (LAMP) was standardized for rapid detection of Clostridium perfringens. Materials and Methods: A total of 120 fecal samples were collected from enterotoxemia suspected lambs were used for screening of C ...
B. Radhika , N. Vinod Kumar , D. Sreenivasulu   +2 more
doaj   +1 more source

Disease-modifying therapies alter gut microbial composition in MS. [PDF]

, 2019
Objective:To determine the effects of the disease-modifying therapies, glatiramer acetate (GA) and dimethyl fumarate (DMF), on the gut microbiota in patients with MS.
Baranzini, Sergio E, Bencosme, Yadira, Brandstadter, Rachel, Casaccia, Patrizia, Cekanaviciute, Egle, Clemente, Jose C, Crabtree-Hartman, Elizabeth, Cree, Bruce AC, Debelius, Justine, Katz Sand, Ilana, Knight, Rob, Ntranos, Achilles, Singh, Sneha, Zhu, Yunjiao   +13 more
core  

Diagnosis and Treatment of Infectious Enteritis in Neonatal and Juvenile Ruminants. [PDF]

, 2018
Common causes of infectious enteritis in neonate and juvenile ruminants include viral, bacterial, and protozoal pathogens. The most common presenting sign in ruminants with infectious enteritis is diarrhea.
Chigerwe, Munashe, Heller, Meera C
core   +1 more source

High-affinity binding of Clostridium perfringens epsilon-toxin to rat brain [PDF]

Infection and Immunity, 1992
125I-epsilon-toxin showed high affinity to rat brain homogenates and synaptosomal membrane fractions, having single binding phases with dissociation constants (Kds) of 2.5 and 3.3 nM, respectively. Treatment of synaptosomal membrane fractions with pronase and neuraminidase lowered the binding of the labeled toxin, whereas treatment with trypsin and ...
M, Nagahama, J, Sakurai
openaire   +2 more sources

Padronização da titulação da toxina épsilon de Clostridium perfringens tipo D em linhagem contínua de células como alternativa ao bioensaio animal Standardization of the titration of the epsilon toxin of Clostridium perfringens type D in cell line as an alternative to animal bioassay

Ciência Rural, 2010
Enterotoxemia, também chamada de doença do rim pulposo, doença que acomete os ruminantes domésticos, é causada pela ação da toxina épsilon produzida pelo Clostridium perfringens tipo D, um anaeróbio comumente isolado do solo e das fezes de animais sadios.
Milton Formiga Souza Júnior, Zélia Inês Portela Lobato, Prhiscylla Sadanã Pires, Rodrigo Otávio Silveira Silva, Felipe Masiero Salvarani, Ronnie Antunes de Assis, Francisco Carlos Faria Lobato   +6 more
doaj  

Targeted Mass Spectrometry Analysis of Clostridium perfringens Toxins

Toxins, 2019
Targeted proteomics recently proved to be a technique for the detection and absolute quantification of proteins not easily accessible to classical bottom-up approaches.
Miloslava Duracova, Jana Klimentova, Alena Myslivcova Fucikova, Lenka Zidkova, Valeria Sheshko, Helena Rehulkova, Jiri Dresler, Zuzana Krocova   +7 more
doaj   +1 more source

Determination of Type and Molecular Identity of Clostridium perfringens Isolated from Patients with Multiple Sclerosis (MS) [PDF]

Journal of Advanced Biomedical Sciences, 2022
Background & Objectives: Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system (CNS). Clostridium perfringens ε-toxin (ETX) can cause emerging complications of MS due to its tendency to the blood-brain barrier.
Maryam Sheykhzade Asadi, Babak Kheirkhah, Nima Bahador   +2 more
doaj  

Calcium enhances binding of Clostridium perfringens epsilon toxin to sulfatide

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2019
Epsilon toxin (Etx) from Clostridium perfringens is synthesized as a very low-active prototoxin form (proEtx) that becomes active upon proteolytic activation and has the capacity to cross the blood-brain barrier (BBB), thereby producing severe neurological effects.
C, Gil, J, Dorca-Arévalo, J, Blasi
openaire   +2 more sources

Effect of Clostridium perfringens Epsilon Toxin on Rat Isolated Aorta [PDF]

Microbiology and Immunology, 1993
AbstractThe effect of Clostridium perfringens epsilon toxin on rat isolated aorta was investigated. The toxin caused contraction of the isolated aorta in a dose‐dependent manner. The toxin induced no contraction of the isolated aorta in low‐Na medium and of the tissue stored at 4 C for 7 days.
M, Nagahama, H, Iida, J, Sakurai
openaire   +2 more sources