Results 101 to 110 of about 396,299 (201)
In vitro potency test for evaluation of Clostridium perfringens type D epsilon toxoid
Arquivos do Instituto BiológicoThe control of enterotoxemia caused by the epsilon toxin, produced by Clostridium perfringenstype D, is based on vaccination with epsilon toxoid. The potency test for this immunogen is conducted using seroneutralization in mice.
Felipe Masiero Salvarini +6 more
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Modulation of ecdysal cyst and toxin dynamics of two Alexandrium (Dinophyceae) species under small-scale turbulence [PDF]
, 2007 Some dinoflagellate species have shown different physiological responses to certain turbulent conditions. Here we investigate how two levels of turbulent kinetic energy dissipation rates (epsilon = 0.4 and 27 cm(2) s(-3)) affect the PSP toxins and ...
Berdalet, E. +6 more
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Toxins, 2019 Clostridium perfringens toxinotype D, toxinotype E, and gastroenteritis-linked BEC/CPILE-positive strains have never been reported in healthy children. We isolated, whole-genome sequenced and bioinformatically characterised three C. perfringens isolates&#
Raymond Kiu +6 more
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Conductance increases produced by bath application of cholinergic agonists to Electrophorus electroplaques [PDF]
, 1975 When solutions containing agonists are applied to the innervated face of an Electrophorus electroplaque, the membrane's conductance increases. The agonist-induced conductance is increased at more negative membrane potentials.
Changeux, Jean-Pierre +2 more
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BMC Veterinary ResearchBackground Clostridial diseases are common in ruminants all over the world. This study investigated the efficacy of a novel recombinant vaccine developed against enterotoxemia and infectious necrotic hepatitis in sheep.
Dilek Nur Ekinoğlu +5 more
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Biochemical and Pharmacological Studies of Clostridium perfringens .EPSILON.-Toxin.
Nippon Saikingaku Zasshi, 1996 D型ウエルシュ菌のe毒素は, 致死, 壊死作用を有するタンパク毒素で, 本菌によるヒツジの腸性中毒症の病原因子と考えられている。本研究では, e毒素の作用機構解明の手がかりを得るため, e毒素の in vivo と in vitro における作用, さらに構造と機能について検討した。まず, e毒素をラットに投与すると末梢血管の収縮による急激な血圧上昇が認められること, さらに本毒素は, in vitro で血管, 回腸などの摘出平滑筋組織を収縮させることを明らかにした。この作用は毒素が神経系にNa+の流入を促進し, その結果, 神経伝達物質が遊離, そしてCa2+チャンネルが活性化されて引き起こされることが判明した。一方, e毒素は脳組織において1種類のシアロ糖タンパク質に特異的に結合すること ...
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Toxins, 2010 The Clostridium perfringens epsilon toxin, a select agent, is responsible for a severe, often fatal enterotoxemia characterized by edema in the heart, lungs, kidney, and brain. The toxin is believed to be an oligomeric pore-forming toxin.
Mark S. McClain +2 more
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The Clostridium perfringens Epsilon Toxin as a Bioterrorism Weapon [PDF]
Journal of Microbial & Biochemical Technology, 2014 The Clostridium perfringens epsilon toxin made by the microorganism true bacteria could be a doubtless fatal bioterrorism weapon. If used effectively, this agent might cause important morbidity and mortality and, because of a scarcity of existing analysis into the result of this poison in humans, no therapeutic or preventive measures exist as medical ...
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Cryo-EM structure of lysenin pore elucidates membrane insertion by an aerolysin family protein [PDF]
, 2016 Lysenin from the coelomic fluid of the earthworm Eisenia fetida belongs to the aerolysin family of small β-pore-forming toxins (β-PFTs), some members of which are pathogenic to humans and animals. Despite efforts, a high-resolution structure of a channel
A Yamaji +46 more
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Archives of Razi Institute, 2011 Designing and producing a proper fusion construction is the most important problem of producing large quantities of a properly folded functional protein. This construction should have all necessary components of a real gene.
Goudarzi, H., +6 more
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