Results 81 to 90 of about 278,084 (274)

Dynamic Disulfide Ionogels for Self‐Healing, Transparent, and Elastic E‐Skins

Advanced Materials Technologies, EarlyView.
A dynamic covalent ionogel is designed via polymer–ionic liquid interaction control. The interplay between ionic liquid compatibility, viscosity, and concentration governs polymer segmental dynamics, which in turn regulates disulfide exchange kinetics and mechanical durability.
Min Su Kim, Dong Hyun Park, Jae Yoon Kim, Hyun Kim, Myungwoong Kim, Kyung Gook Cho, Keun Hyung Lee   +6 more
wiley   +1 more source

Sheep immune response against a novel recombinant enterotoxemia and infectious necrotic hepatitis vaccine in Türkiye

BMC Veterinary Research
Background Clostridial diseases are common in ruminants all over the world. This study investigated the efficacy of a novel recombinant vaccine developed against enterotoxemia and infectious necrotic hepatitis in sheep.
Dilek Nur Ekinoğlu, Venhar Çelik, Esra Gül, Hakan Kalender, Hasan Öngör, Burhan Çetinkaya   +5 more
doaj   +1 more source

Biochemical and Pharmacological Studies of Clostridium perfringens .EPSILON.-Toxin.

Nippon Saikingaku Zasshi, 1996
D型ウエルシュ菌のe毒素は, 致死, 壊死作用を有するタンパク毒素で, 本菌によるヒツジの腸性中毒症の病原因子と考えられている。本研究では, e毒素の作用機構解明の手がかりを得るため, e毒素の in vivo と in vitro における作用, さらに構造と機能について検討した。まず, e毒素をラットに投与すると末梢血管の収縮による急激な血圧上昇が認められること, さらに本毒素は, in vitro で血管, 回腸などの摘出平滑筋組織を収縮させることを明らかにした。この作用は毒素が神経系にNa+の流入を促進し, その結果, 神経伝達物質が遊離, そしてCa2+チャンネルが活性化されて引き起こされることが判明した。一方, e毒素は脳組織において1種類のシアロ糖タンパク質に特異的に結合すること ...
openaire   +3 more sources

Resistance of Ovine, Caprine and Bovine Endothelial Cells to Clostridium perfringens type D Epsilon Toxin In Vitro

, 1999
Ovine, caprine and bovine endothelial cells were grown in vitro and challenged with Clostridium perfringens type D epsilon toxin to compare their susceptibility to this toxin.
Kelly, WR, Rolfe, BE, Rolfe, B E, Thomas, AC, Smith, N J, Uzal, FA, Uzal, F A, Kelly, W R, Smith, NJ, Thomas, A C   +9 more
core   +1 more source

Production of epsilon toxin secreted by Clostridium perfringens type D under different culture conditions

, 2022
Clostridium perfringens hayvanlarda ve insanlarda dizanteri, gazlı kangren gibi çeşitli hastalıklara neden olan Gram pozitif, çubuk şeklinde, anaerobik, spor oluşturan patojenik bir bakteridir. C. perfringens tip B ve tip D tarafından salgılanan epsilon (
Sevimli, Fethiye
core   +1 more source

Comparative genomics of Shiga toxin encoding bacteriophages [PDF]

, 2012
Background Stx bacteriophages are responsible for driving the dissemination of Stx toxin genes (stx) across their bacterial host range. Lysogens carrying Stx phages can cause severe, lifethreatening disease and Stx toxin is an integral virulence factor.
Alan J McCarthy, Darby Alistair C, Alistair C Darby, Allison Heather E, Rooks David J, Rooks, David, Smith, Darren, Paul CM Fogg, Thomson, Nicholas, David J Rooks, Smith Darren L, McCarthy Alan J, McCarthy, Alan, Heather E Allison, Darren L Smith, Allison, Heather, Fogg Paul CM, Nick R Thomson, Fogg, Paul, Darby, Alistair, Thomson Nick R   +20 more
core   +1 more source

Programmable Variable‐Stiffness Multilayer Elastomer Composites With High‐Aspect‐Ratio Low‐Melting‐Point Alloy Inclusions

Advanced Materials Technologies, EarlyView.
High‐aspect‐ratio low‐melting‐point alloy inclusions are embedded within multilayer silicone laminates to create thermally programmable stiffness. Sequential activation of alloy‐rich layers produces four distinct mechanical states and reconfigures tendon‐driven actuator trajectories under the same load.
Palpolage Don Shehan Hiroshan Gunawardane, Gyan Edbert Zesiro, Hao Zhou, Gursel Alici, Mu Chiao   +4 more
wiley   +1 more source

Genomic Analysis of Clostridium perfringens BEC/CPILE-Positive, Toxinotype D and E Strains Isolated from Healthy Children

Toxins, 2019
Clostridium perfringens toxinotype D, toxinotype E, and gastroenteritis-linked BEC/CPILE-positive strains have never been reported in healthy children. We isolated, whole-genome sequenced and bioinformatically characterised three C. perfringens isolates&#
Raymond Kiu, Kathleen Sim, Alex Shaw, Emma Cornwell, Derek Pickard, J. Simon Kroll, Lindsay J. Hall   +6 more
doaj   +1 more source

Determination of Type and Molecular Identity of Clostridium perfringens Isolated from Patients with Multiple Sclerosis (MS) [PDF]

Journal of Advanced Biomedical Sciences, 2022
Background & Objectives: Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system (CNS). Clostridium perfringens ε-toxin (ETX) can cause emerging complications of MS due to its tendency to the blood-brain barrier.
Maryam Sheykhzade Asadi, Babak Kheirkhah, Nima Bahador   +2 more
doaj  

Evidence for a Prepore Stage in the Action of Clostridium perfringens Epsilon Toxin

PLoS ONE, 2011
Clostridium perfringens epsilon toxin (ETX) rapidly kills MDCK II cells at 37°C, but not 4°C. The current study shows that, in MDCK II cells, ETX binds and forms an oligomeric complex equally well at 37°C and 4°C but only forms a pore at 37°C. However, the complex formed in MDCK cells treated with ETX at 4°C has the potential to form an active pore ...
Robertson, SL, Li, J, Uzal, FA, McClane, BA   +3 more
openaire   +6 more sources