Results 81 to 90 of about 396,299 (201)

Epsilon toxin-producing Clostridium perfringens colonize the MS gut and epsilon toxin overcomes immune privilege

, 2023
Multiple sclerosis (MS) is a complex disease of the CNS thought to require an environmental trigger. Gut dysbiosis is common in MS, but specific causative species are unknown. To address this knowledge gap, we used sensitive and quantitative PCR detection to show that people with MS were more likely to harbor and show a greater abundance of epsilon ...
Ma, Yinghua, Sannino, David, Linden, Jennifer R, Haigh, Sylvia, Zhao, Baohua, Grigg, John B, Zumbo, Paul, Dündar, Friederike, Butler, Daniel J, Profaci, Caterina P, Telesford, Kiel M, Winokur, Paige N, Rumah, Kareem R, Gauthier, Susan A, Fischetti, Vincent A, McClane, Bruce A, Uzal, Francisco A, Zexter, Lily, Mazzucco, Michael, Rudick, Richard, Danko, David, Balmuth, Evan, Nealon, Nancy, Perumal, Jai, Kaunzner, Ulrike W, Brito, Ilana L, Chen, Zhengming, Xiang, Jenny Z, Betel, Doron, Daneman, Richard, Sonnenberg, Gregory F, Mason, Christopher E, Vartanian, Timothy   +32 more
openaire   +2 more sources

ANALYSIS OF THE PRESENCE OF TOXINS FROM ESCHERICHIA COLI, CLOSTRIDIUM PERFRINGENS, C. DIFFICILE IN BULK FEEDS OF SAINT-PETERSBURG AND LENINGRAD REGION

Siberian Journal of Life Sciences and Agriculture
Background. Undesirable microflora can enter forage crops during harvesting with soil, which can contain various pathogenic microorganisms, including clostridia and enterobacteria, which enter it when manure is applied to fields as fertilizer.
Valentina A. Filippova, Elena A. Yildirim, Larisa A. Ilina, Georgy Yu. Laptev, Andrey V. Dubrovin, Vasily A. Zaikin, Ksenia A. Kalitkina, Alisa S. Dubrovina, Ivan G. Malakhov, Irina A. Klyuchnikova   +9 more
doaj   +1 more source

Toxin genotyping of Clostridium perfringens field strains isolated from healthy and diseased chickens

Italian Journal of Animal Science, 2010
Clostridium perfringens is well known as the aetiological agent of necrotic enteritis in chicken. Type A and type C are considered the C. perfringens toxin types responsible for this disease.
Luca Bano, Barbara Marcon, Tiziana Ferro, Francesca Bettini, Monia Cocchi, Cosetta Bacchin, Fabrizio Agnoletti, Ilenia Drigo   +7 more
doaj   +1 more source

Enterotoxemia em bovino Bovine enterotoxaemia

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2006
This report describes a case of bovine enterotoxaemia in Morro da Garça, Minas Gerais, Brazil. Clostridium perfringens type D was isolated in pure culture and was characterized by biochemical reactions and PCR.
F.C.F. Lobato, R.A. Assis, V.L.V. Abreu, M.F. Souza Jr., C.G.R.D. Lima, F.M. Salvarani   +5 more
doaj   +1 more source

Functional Analysis of Neutralizing Antibodies against Clostridium perfringens Epsilon-Toxin [PDF]

Infection and Immunity, 2007
ABSTRACT The Clostridium perfringens epsilon-toxin causes a severe, often fatal illness (enterotoxemia) characterized by cardiac, pulmonary, kidney, and brain edema. In this study, we examined the activities of two neutralizing monoclonal antibodies against the C.
Mark S, McClain, Timothy L, Cover
openaire   +2 more sources

An update on the human and animal enteric pathogen Clostridium perfringens [PDF]

, 2018
Clostridium perfringens, a rapid-growing pathogen known to secrete an arsenal of >20 virulent toxins, has been associated with intestinal diseases in both animals and humans throughout the past century.
Cavalieri, A. V. G., Colonius, T., Deschamps, C. J., Lajús, F. C., Jr., Sinha, A.   +4 more
core   +3 more sources

Cloning and expression of Clostridium perfringenstype D vaccine strain epsilon toxin gene in E. coli as a recombinant vaccine candidate

Iranian Journal of Microbiology, 2016
Background and Objectives: Clostridium perfringens, a Gram-positive obligate anaerobic bacterium, is able to form resistant spores which are widely distributed in the environment. C.
Parastoo Aziminia, Reza Pilehchian Langroudi, Kasra Esmaeilnia   +2 more
doaj  

Inhibition of Epsilon Toxin-Producing Clostridium perfringens with a JuiceBased Probiotic Medical Food for Dietary Management of Multiple Sclerosis

International Journal of Preventive Medicine and Care
Background Multiple sclerosis (MS) is the most common disabling neurological disease in young adults, with symptom onset generally occurring between the ages of 20 and 40 years.

semanticscholar   +1 more source

Clostridium perfringens epsilon toxin: Toxic effects and mechanisms of action

Biosafety and Health, 2019
Clostridium perfringens ε-toxin (ETX) is the main toxin resulting in enterotoxemia of sheep and goats. ETX can cause lesions of multiple organs, such as hydropericardium, pulmonary edema and focal symmetrical encephalomalcia (FSE).
Wenwen Xin, Jinglin Wang
doaj   +1 more source

First insights into a type II toxin-antitoxin system from the clinical isolate Mycobacterium sp. MHSD3, similar to epsilon/zeta systems. [PDF]

PLoS ONE, 2017
A putative type II toxin-antitoxin (TA) system was found in the clinical isolate Mycobacterium sp. MHSD3, a strain closely related to Mycobacterium chelonae.
Daniel Jaén-Luchoro, Francisco Aliaga-Lozano, Rosa Maria Gomila, Margarita Gomila, Francisco Salvà-Serra, Jorge Lalucat, Antoni Bennasar-Figueras   +6 more
doaj   +1 more source