Results 191 to 200 of about 9,966 (237)

Strategic construction of fluorinated surroundings in NIR‐II‐emissive organic semiconducting agents for amplifying cancer phototheranostics

FlexMat, EarlyView.
The development of conventional phototheranostic nanomedicines suffers from an intrinsic trade‐off between NIR‐II fluorescence emission and phototherapeutic effects, leading to poor overall efficacy. Herein, we propose an innovative fluorination strategy by constructing fluorinated surroundings in NIR‐II‐emissive organic semiconducting agents to ...
Xiaoming Hu, Achen Qin, Caijun Zhu, Jinshuo Mi, Zejing Chen, Jiaying Shao, Zhen Li, Zhen Yang   +7 more
wiley   +1 more source

The research progress in polyethylene oxide polymer electrolytes

FlexMat, EarlyView.
Polyethylene oxide (PEO) has become the mainstream matrix material for solid polymer electrolytes (SPEs) due to its excellent lithium salt complexation ability and processability. However, its high crystallinity results in low ionic conductivity at room temperature and difficulty in suppressing lithium dendrite growth, which significantly hinders the ...
Ying Wei, Yueting Pu, Zheng Zhang, Yang Li, Cheng Yang, Fangju Tao, Xinxin Han, Fangfang Wu, Linghai Xie   +8 more
wiley   +1 more source

Longitudinal Swallowing and Salivary Changes With CLR 131 and Re‐Irradiation in Recurrent Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Background Patients with recurrent head and neck cancer (HNC) often present with severe, persistent dysphagia and xerostomia following prior chemoradiation. Although swallowing impairments and salivary dysfunction have been reported in this population, prior longitudinal studies have not examined changes in salivary composition or how these ...
Jenni Wu, Sara Gustafson, Meredith Hyun, Roxana Alexandridis, Mark Nicosia, Timothy McCulloch, Justine Bruce, Randall Kimple, Nicole Rogus‐Pulia   +8 more
wiley   +1 more source

Toxin-Host Interaction of <i>Clostridium</i> Toxins. [PDF]

Toxins (Basel)
Dorca-Arévalo J.
europepmc   +1 more source

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Amino groups in Clostridium perfringens epsilon prototoxin and epsilon toxin

Microbial Pathogenesis, 1986
Modification with succinic anhydride (SA) of Clostridium perfringens epsilon prototoxin or toxin resulted in a loss of activation by trypsin or lethal activity, respectively. The prototoxin was more sensitive to succinylation than the toxin. On the other hand, the succinylated prototoxin was activated and cleaved by chymotrypsin, but not by trypsin ...
Masahiro Nagahama, M Nagahama, J Sakurai   +2 more
exaly   +3 more sources

Clostridium perfringens epsilon toxin: The third most potent bacterial toxin known

Anaerobe, 2014
Epsilon toxin (ETX) is produced by Clostridium perfringens type B and D strains and causes enterotoxemia, a highly lethal disease with major impacts on the farming of domestic ruminants, particularly sheep. ETX belongs to the aerolysin-like pore-forming toxin family.
CARLOS Chavéz-Olortegui, Ricardo Andrez Machado de Ávila, Guilherme Guerra Alves   +2 more
exaly   +3 more sources

Direct Visualization of the Dynamic Process of Epsilon Toxin on Hemolysis

Small Methods, 2023
AbstractHemolysis is the process of rupturing erythrocytes (red blood cells) by forming nanopores on their membranes using hemolysins, which then impede membrane permeability. However, the self‐assembly process before the state of transmembrane pores and underlying mechanisms of conformational change are not fully understood.
Bin Ji, Jianxiang Huang, Kexuan Zou, Meijun Liu, Yufeng Pei, Jing Huang, Yong Wang, Jinglin Wang, Ruhong Zhou, Wenwen Xin, Jie Song   +10 more
openaire   +2 more sources

Detection of Clostridium perfringens epsilon toxin by elisa

Research in Veterinary Science, 1987
An enzyme-linked immunosorbent assay (ELISA) has been developed as an alternative to neutralisation tests in mice to detect Clostridium perfringens type D epsilon toxin in the intestinal contents of animals which have died from suspected enterotoxaemia. The test was sensitive and quantitative and gave excellent agreement with the mouse protection test.
R D, Naylor, P K, Martin, R T, Sharpe
openaire   +2 more sources

Carboxyl groups in Clostridium perfringens epsilon toxin

Microbial Pathogenesis, 1987
The maximal number of norleucine methyl ester (NME) incorporated into carboxyl groups in epsilon toxin of Clostridium perfringens by the carbodiimide-nucleophile procedure was 7 and 17 in the absence and presence of 8 M urea, respectively. The introduction of 3-4 nucleophilic modifying agents such as NME, glycine methyl ester or taurine into carboxyl ...
J, Sakurai, M, Nagahama
openaire   +2 more sources

Epsilon toxin: a fascinating pore‐forming toxin

The FEBS Journal, 2011
Epsilon toxin (ETX) is produced by strains of Clostridium perfringens classified as type B or type D. ETX belongs to the heptameric β‐pore‐forming toxins including aerolysin and Clostridium septicum alpha toxin, which are characterized by the formation of a pore through the plasma membrane of eukaryotic cells consisting in a β‐barrel of 14 amphipatic β 
openaire   +2 more sources