Results 211 to 220 of about 9,854 (235)

Distribution of labeled Clostridium perfringens epsilon toxin in mice

Toxicon, 1991
The in vivo distribution of labeled Clostridium perfringens epsilon toxin after i.v. administration to mice was investigated. High amounts of radioactivity were found in the kidneys and the brain, and small amounts were in the heart, lungs, liver and stomach.
M, Nagahama, J, Sakurai
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Enterocolitis in goats associated with enterotoxaemia in the perspective of two toxins: Epsilon toxin and beta-2 toxin – An immunohistochemical and molecular study

Comparative Immunology, Microbiology and Infectious Diseases, 2022
Caprine intestinal diseases associated with clostridia are generally caused by Cpa and Etx encoded alpha (α) and epsilon (ε) toxinotypes of Clostridium perfringens type D respectively. A recent study on goat enterocolitis, demonstrated that the incidence of Clostridium perfringens type-D toxinotype and beta 2 toxins is high, suggesting its role in ...
N K, Gangwar, R V S, Pawaiya, K, Gururaj, Dimple, Andani, A, Kumar, R, Singh, A P, Singh   +6 more
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Clostridium perfringens Epsilon Toxin: Structural and Mechanistic Insights

2016
Epsilon toxin (ETX) is produced by strains of Clostridium perfringens classified as type B or D. ETX belongs to the heptameric β-pore-forming toxins including Aeromonas aerolysin and Clostridium septicum alpha toxin, which are characterized by the formation of a pore through the plasma membrane of eukaryotic cells and containing a β-barrel composed of ...
Popoff, Michel R., Stiles, Bradley, Poulain, Bernard   +2 more
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Cellular vacuolation induced by Clostridium perfringens epsilon‐toxin

The FEBS Journal, 2011
The epsilon‐toxin of Clostridium perfringens forms a heptamer in the membranes of Madin–Darby canine kidney cells, leading to cell death. Here, we report that it caused the vacuolation of Madin–Darby canine kidney cells. The toxin induced vacuolation in a dose‐dependent and time‐dependent manner. The monomer of the toxin formed oligomers on lipid rafts
Masahiro, Nagahama, Yukari, Itohayashi, Hideki, Hara, Masahiro, Higashihara, Yusuke, Fukatani, Teruhisa, Takagishi, Masataka, Oda, Keiko, Kobayashi, Ichiro, Nakagawa, Jun, Sakurai   +9 more
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Molecular basis of toxicity ofClostridium perfringensepsilon toxin

The FEBS Journal, 2011
Clostridium perfringensε‐toxin is produced by toxinotypes B and D strains. The toxin is the aetiological agent of dysentery in newborn lambs but is also associated with enteritis and enterotoxaemia in goats, calves and foals. It is considered to be a potential biowarfare or bioterrorism agent by the US Government Centers for Disease Control and ...
Monika, Bokori-Brown, Christos G, Savva, Sérgio P, Fernandes da Costa, Claire E, Naylor, Ajit K, Basak, Richard W, Titball   +5 more
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Vaccines against the category B toxins: Staphylococcal enterotoxin B, epsilon toxin and ricin

Advanced Drug Delivery Reviews, 2005
The threat of bioterrorism worldwide has accelerated the demand for the development of therapies and vaccines against the Category B toxins: staphylococcal enterotoxin B (SEB), epsilon toxin (ETX) produced by Clostridium perfringens types B and D, and ricin, a natural product of the castor bean.
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The Clostridium perfringens epsilon-toxin

Reviews in Medical Microbiology, 1997
Dean Payne, E. Diane Williamson, Richard W. Titball   +2 more
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Study of epsilon toxin: production and purification

Toxicon, 1997
V. Morineaux, D. Hilaire
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Epsilon toxin as a causative agent in MS

Journal of the Neurological Sciences, 2017
D. Raciborska, B. Turner, R. Titball, M. Bokori-Brown, S. Wagley, S. Gnanapavan, N. Lewis   +6 more
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Clostridium perfringens Toxin (Epsilon Toxin) Attack

2016
Mariann Nocera, Lynne Barkley Burnett, Siraj Amanullah   +2 more
openaire   +1 more source