A novel mechanism of programmed cell death in bacteria by toxin-antitoxin systems corrupts peptidoglycan synthesis. [PDF]
PLoS Biology, 2011 Most genomes of bacteria contain toxin-antitoxin (TA) systems. These gene systems encode a toxic protein and its cognate antitoxin. Upon antitoxin degradation, the toxin induces cell stasis or death.
Hannes Mutschler +3 more
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Effects of Clostridium perfringens iota toxin in the small intestine of mice [PDF]
, 2017 Iota toxin is a binary toxin solely produced by Clostridium perfringens type E strains, and is structurally related to CDT from C. difficile and CST from C. spiroforme.
Bruzzone, Octavio Augusto +8 more
core +1 more source
Solubilization, Activation, and Insecticidal Activity of Bacillus thuringiensis Serovar thompsoni HD542 Crystal Proteins [PDF]
, 2008 Cry15Aa protein, produced by Bacillus thuringiensis serovar thompsoni HD542 in a crystal together with a 40 kDa accompanying protein is one of a small group of non-typical, less well-studied members of the Cry family of insecticidal proteins, and may ...
Naimov, S. +5 more
core +1 more source
Enhancing the efficacy of cytotoxic agents for cancer therapy using photochemical internalisation. [PDF]
, 2015 Photochemical internalisation (PCI) is a technique for improving cellular delivery of certain bioactive agents which are prone to sequestration within endolysosomes.
Adigbli +69 more
core +1 more source
Molecular Detection of Clostridium perfringens Type D Alpha and Epsilon Toxin Genes from Various Tissues in Lambs [PDF]
Pakistan Veterinary Journal, 2013 Different tissues including duodenal scrapings, liver, lungs and kidneys of each infected (n=6) and control (n=4) lambs were subjected to PCR for the identification of alpha and epsilon toxin genes of Clostridium perfringens type D.
Azam Ali Nasir1,3, Muhammad Younus2,*, Muti-ur-Rehman3, Muhammad Latif3, Asif Rashid1, Rashid Ahmad1 and Muhammad Abbas1
doaj
Journal of Infection in Developing Countries, 2009 BACKGROUND: Enterotoxaemia produced by Clostridium perfringens A, C and D is an important cause of mortality in young llamas. There is no data on antibody responses following vaccination with epsilon toxin. METHODOLOGY: Twenty-six L.
Adriana B. Bentancor +3 more
doaj +1 more source
The synergistic necrohemorrhagic action of Clostridium perfringens perfringolysin and alpha toxin in the bovine intestine and against bovine endothelial cells [PDF]
, 2013 Bovine necrohemorrhagic enteritis is a major cause of mortality in veal calves. Clostridium perfringens is considered as the causative agent, but there has been controversy on the toxins responsible for the disease.
Deprez, Piet +10 more
core +2 more sources
Conjugative plasmids of Neisseria gonorrhoeae. [PDF]
PLoS ONE, 2010 Many clinical isolates of the human pathogen Neisseria gonorrhoeae contain conjugative plasmids. The host range of these plasmids is limited to Neisseria species, but presence of a tetracycline (tetM) determinant inserted in several of these plasmids is ...
Emilia Pachulec, Chris van der Does
doaj +1 more source
Effect ofClostridium perfringensepsilon toxin on MDCK cells [PDF]
FEMS Immunology & Medical Microbiology, 2001 Epsilon toxin is one of the major lethal toxins produced by Clostridium perfringens type D and B. It is responsible for a rapidly fatal disease in sheep and other farm animals. Many facts have been published about the physical properties and the biological activities of the toxin, but the molecular mechanism of the action inside the cells remains ...
E, Borrmann, H, Günther, H, Köhler
openaire +3 more sources
Onderstepoort Journal of Veterinary Research, 2017 Enterotoxaemia (pulpy kidney) is a common bacterial disease of sheep caused by Clostridium perfringens type D epsilon toxin. It has mortality rates of up to 30% in non-vaccinated animals.
Tinyiko Mokoena +6 more
doaj +1 more source