Isolation of Clostridium perfringens type B in an individual at first clinical presentation of multiple sclerosis provides clues for environmental triggers of the disease. [PDF]
PLoS ONE, 2013 We have isolated Clostridium perfringens type B, an epsilon toxin-secreting bacillus, from a young woman at clinical presentation of Multiple Sclerosis (MS) with actively enhancing lesions on brain MRI.
Kareem Rashid Rumah +3 more
doaj +1 more source
, 2021 The physician and patient come into close contact during botulinum toxin treatments, increasing the chances of COVID-19 infection. Therefore, it is essential to use an effective injection method that can prevent infection with SARS-CoV-2 virus.
Altavista, Maria Concetta +4 more
core +1 more source
A novel mechanism of programmed cell death in bacteria by toxin-antitoxin systems corrupts peptidoglycan synthesis. [PDF]
PLoS Biology, 2011 Most genomes of bacteria contain toxin-antitoxin (TA) systems. These gene systems encode a toxic protein and its cognate antitoxin. Upon antitoxin degradation, the toxin induces cell stasis or death.
Hannes Mutschler +3 more
doaj +1 more source
Characterization of quinolones resistant Clostridium perfringens toxinotype D
Pakistan Journal of Pharmaceutical Sciences, 2023 Clostridium perfringens toxins play role in causing pulpy kidney disease poisoning as well enterotoxaemia. To combat antimicrobial resistance: curbing use, regulations and execution to antimicrobial usage in food along with withdrawal period is necessary.
Madeeha Tariq +4 more
doaj +1 more source
Gas phase characterization of the noncovalent quaternary structure of Cholera toxin and the Cholera toxin B subunit pentamer [PDF]
, 2006 Cholera toxin (CTx) is an AB5 cytotonic protein that has medical relevance in cholera and as a novel mucosal adjuvant. Here, we report an analysis of the noncovalent homopentameric complex of CTx B chain (CTx B5) using electrospray ionization triple ...
Jennings, Keith R. +15 more
core +1 more source
The light chain of tetanus toxin inhibits calcium-dependent vasopressin release from permeabilized nerve endings [PDF]
, 1992 The effects of tetanus toxin and its light and heavy chain subunits on vasopressin release were investigated in digitonin-permeabilized neurosecretory nerve terminals isolated from the neural lobe of the rat pituitary gland.
Weller, U. +5 more
core +1 more source
Molecular Detection of Clostridium perfringens Type D Alpha and Epsilon Toxin Genes from Various Tissues in Lambs [PDF]
Pakistan Veterinary Journal, 2013 Different tissues including duodenal scrapings, liver, lungs and kidneys of each infected (n=6) and control (n=4) lambs were subjected to PCR for the identification of alpha and epsilon toxin genes of Clostridium perfringens type D.
Azam Ali Nasir1,3, Muhammad Younus2,*, Muti-ur-Rehman3, Muhammad Latif3, Asif Rashid1, Rashid Ahmad1 and Muhammad Abbas1
doaj
Journal of Infection in Developing Countries, 2009 BACKGROUND: Enterotoxaemia produced by Clostridium perfringens A, C and D is an important cause of mortality in young llamas. There is no data on antibody responses following vaccination with epsilon toxin. METHODOLOGY: Twenty-six L.
Adriana B. Bentancor +3 more
doaj +1 more source
Conjugative plasmids of Neisseria gonorrhoeae. [PDF]
PLoS ONE, 2010 Many clinical isolates of the human pathogen Neisseria gonorrhoeae contain conjugative plasmids. The host range of these plasmids is limited to Neisseria species, but presence of a tetracycline (tetM) determinant inserted in several of these plasmids is ...
Emilia Pachulec, Chris van der Does
doaj +1 more source
Exploring the functional domain and the target of the tetanus toxin light chain in neurohypophysial terminals [PDF]
, 1994 The tetanus toxin light chain blocks calcium induced vasopressin release from neurohypophysial nerve terminals. Here we show that histidine residue 233 within the putative zinc binding motif of the tetanus toxin light chain is essential for the ...
Weller, U. +7 more
core +1 more source