A small bioactive glycoside inhibits epsilon toxin and prevents cell death [PDF]
Disease Models & Mechanisms, 2019 Clostridium perfringens epsilon toxin (Etx) is categorized as the third most lethal bioterrorism agent by the Centers for Disease Control and Prevention (CDC), with no therapeutic counter measures available for humans.
Abhishek Shivappagowdar +11 more
doaj +2 more sources
Untersuchung des Epsilon-Toxins und Mutanten des Epsilon-Toxins aus Clostridium perfringens auf Kanalbildung [PDF]
, 2006 Ziel dieser Arbeit war die biophysikalische Charakterisierung der Bindekomponente des Epsilon-Toxins und der Epsilon-Toxin-Mutanten mit Hilfe künstlicher Lipid-Bilayer-Messungen. Es galt herauszufinden, welcher Teil des Epsilon-Toxins für die Kanalbildung verantwortlich ist, um somit die kanalbildende Domäne definieren zu können.
Seitz, Steffen
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Cloning and Expression of a Fusion Protein Containing Highly Epitopic Regions of Clostridium perfringens Epsilon Toxin and Clostridium novyi Alpha Toxin [PDF]
Journal of Cell and Molecular Research, 2021 Clostridium perfringens and novyi species are two important toxin-producing pathogens which pose a risk to the livestock health. Epsilon and alpha toxins are major toxins of these two pathogens, respectively. Advances in current vaccine industrialization
Mohsen Mehrvarz +3 more
doaj +1 more source
Molecular characterization and toxins optimization of indigenous clostridium perfringens toxinotype b isolated from lamb dysentery clinical cases [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2023 Clostridium perfringens toxinotype B is causative agent of lamb dysentery in Pakistan. For assessment of gene expression, it is preferred to optimize toxin production potential of indigenous isolates.
Mian Muhammad Khubaib SATTAR +5 more
doaj +1 more source
Tryptophan content of Clostridium perfringens epsilon toxin [PDF]
Infection and Immunity, 1985 The tryptophan content of Clostridium perfringens epsilon toxin was investigated. When the tryptophan content was determined by amino acid analysis after the hydrolysis of epsilon prototoxin with methanesulfonic acid containing 3-(2-aminoethyl)indole and by the spectrophotometric method with N-bromosuccinimide, the number of tryptophan residues was ...
J, Sakurai, M, Nagahama
openaire +2 more sources
Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin [PDF]
Brazilian Journal of Microbiology, 2017 Carlos Chavéz-Olortegui +2 more
exaly +2 more sources
Clostridium perfringensepsilon toxin H149A mutant as a platform for receptor binding studies [PDF]
, 2013 Clostridium perfringens epsilon toxin (Etx) is a pore-forming toxin responsible for a severe and rapidly fatal enterotoxemia of ruminants. The toxin is classified as a category B bioterrorism agent by the U.S.
Titball, R.W. +21 more
core +1 more source
Clostridium perfringens epsilon toxin mutant Y30A-Y196A as a recombinant vaccine candidate against enterotoxemia [PDF]
, 2014 Epsilon toxin (Etx) is a β-pore-forming toxin produced by Clostridium perfringens toxinotypes B and D and plays a key role in the pathogenesis of enterotoxemia, a severe, often fatal disease of ruminants that causes significant economic losses to the ...
Bokori-Brown, M. +25 more
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Use of Esienia fetida Worms to Produce Peptone for Clostridium perfringens Vaccine Production [PDF]
Archives of Razi Institute, 2023 Concurrent with an increase in the human population on the earth, more than ever, the creation of energy and maintenance of health is necessary, and nowadays, various sources of energy supply are being developed. The general global view in this regard is
H Noruzy Moghadam +5 more
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Structural insights into Clostridium perfringens delta toxin pore formation [PDF]
, 2013 Clostridium perfringens Delta toxin is one of the three hemolysin-like proteins produced by C. perfringens type C and possibly type B strains. One of the others, NetB, has been shown to be the major cause of Avian Nectrotic Enteritis, which following the
Claire E Naylor +37 more
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