Results 41 to 50 of about 9,966 (237)

Mapping Protein–Protein Interactions of the Resistance-Related Bacterial Zeta Toxin–Epsilon Antitoxin Complex (ε2ζ2) with High Affinity Peptide Ligands Using Fluorescence Polarization

Toxins, 2016
Toxin–antitoxin systems constitute a native survival strategy of pathogenic bacteria and thus are potential targets of antibiotic drugs. Here, we target the Zeta–Epsilon toxin–antitoxin system, which is responsible for the stable maintenance of certain ...
María Isabel Fernández-Bachiller, Iwona Brzozowska, Norbert Odolczyk, Urszula Zielenkiewicz, Piotr Zielenkiewicz, Jörg Rademann   +5 more
doaj   +1 more source

Increasing Inter‐Micellar Connectivity Toughens and Imparts Cooling‐Induced Shape Memory in Micellar Hydrogels

Advanced Functional Materials, EarlyView.
Oligomerizing Pluronic triblock copolymers provides a processing strategy for tuning the mechanical properties and stimuli‐responsive behaviors of micellar hydrogels. Varying oligomer fraction produces hydrogels spanning brittle to highly extensible responses; maintaining micellar architectures enables cooling‐induced reverse thermal shape memory and ...
Gourav Kumbhojkar, Eric Yang, Arman Moussavi, EunBi Oh, Haeji Kim, Wei Chen, Junsoo Kim, Sinan Keten, Ryan L. Truby   +8 more
wiley   +1 more source

Clostridium perfringens Epsilon Toxin Causes Selective Death of Mature Oligodendrocytes and Central Nervous System Demyelination

mBio, 2015
Clostridium perfringens epsilon toxin (ε-toxin) is responsible for a devastating multifocal central nervous system (CNS) white matter disease in ruminant animals. The mechanism by which ε-toxin causes white matter damage is poorly understood.
Jennifer R. Linden, Yinghua Ma, Baohua Zhao, Jason Michael Harris, Kareem Rashid Rumah, Nicole Schaeren-Wiemers, Timothy Vartanian   +6 more
doaj   +1 more source

Effect of Clostridium perfringens epsilon toxin on the cardiovascular system of rats [PDF]

Infection and Immunity, 1983
Pressor activity was demonstrated by the intravenous injection of purified epsilon toxin of Clostridium perfringens type D but not by that of epsilon prototoxin. The activity was completely abolished by C. perfringens type B or D antiserum, but not by type A, C, or E antiserum.
J, Sakurai, M, Nagahama, Y, Fujii
openaire   +2 more sources

Interaction‐Driven Assembly Pathways in Heterogeneous Active Microrobotic Systems

Advanced Functional Materials, EarlyView.
Peanut‐ and cube‐shaped light‐powered microrobots exhibit distinct magnetic and photocatalytic responses that determine their heterogeneous self‐assembly. In the dark, magnetic dipole interactions drive colloidal copolymerization with cubes acting as nucleation centers, whereas under light irradiation, phoretic interactions compete with magnetic ...
Domenico Calabrò, Roshan Velluvakandy, Martin Pumera, Francesco Priolo, Salvo Mirabella, Mario Urso   +5 more
wiley   +1 more source

Clostridium Perfringens Epsilon Toxin Binds to Membrane Lipids and Its Cytotoxic Action Depends on Sulfatide. [PDF]

PLoS ONE, 2015
Epsilon toxin (Etx) is one of the major lethal toxins produced by Clostridium perfringens types B and D, being the causal agent of fatal enterotoxemia in animals, mainly sheep and goats.
Carles Gil, Jonatan Dorca-Arévalo, Juan Blasi   +2 more
doaj   +1 more source

Oxygels: Tunable Phosphorescent Hydrogels for Cherenkov‐Excited Luminescence Imaging (CELI) of Oxygen

Advanced Healthcare Materials, EarlyView.
Biocompatible hydrogels with covalently embedded near‐infrared phosphorescent probes enable local tissue pO2 quantification by means of Cherenkov‐excited luminescence imaging (CELI), where optical excitation occurs within tissues upon irradiation with high‐energy electron beams.
Simin Belali, Marien Iliza Ochoa Mendoza, Matthew S. Reed, Danylo Mykhalchuk, Annemarie Lang, Joel D. Boerckel, Brian W. Pogue, Sergei A. Vinogradov   +7 more
wiley   +1 more source

ANALYSIS OF THE PRESENCE OF TOXINS FROM ESCHERICHIA COLI, CLOSTRIDIUM PERFRINGENS, C. DIFFICILE IN BULK FEEDS OF SAINT-PETERSBURG AND LENINGRAD REGION

Siberian Journal of Life Sciences and Agriculture
Background. Undesirable microflora can enter forage crops during harvesting with soil, which can contain various pathogenic microorganisms, including clostridia and enterobacteria, which enter it when manure is applied to fields as fertilizer.
Valentina A. Filippova, Elena A. Yildirim, Larisa A. Ilina, Georgy Yu. Laptev, Andrey V. Dubrovin, Vasily A. Zaikin, Ksenia A. Kalitkina, Alisa S. Dubrovina, Ivan G. Malakhov, Irina A. Klyuchnikova   +9 more
doaj   +1 more source

Kinetics of epsilon antitoxin antibodies in different strategies for active immunization of lambs against enterotoxaemia

Pesquisa Veterinária Brasileira, 2013
Enterotoxaemia, a common disease that affects domestic small ruminants, is mainly caused by the epsilon toxin of Clostridium perfringens type D. The present study tested four distinct immunization protocols to evaluate humoral response in lambs, a ...
Heni F. Costa, Selene D. Babboni, Carlos F.C. Rodrigues, Carlos R. Padovani, Iveraldo S. Dutra, Silvana C. Paulan, José R. Modolo   +6 more
doaj   +1 more source

Epsilon toxin-producing Clostridium perfringens colonize the MS gut and epsilon toxin overcomes immune privilege

, 2023
Multiple sclerosis (MS) is a complex disease of the CNS thought to require an environmental trigger. Gut dysbiosis is common in MS, but specific causative species are unknown. To address this knowledge gap, we used sensitive and quantitative PCR detection to show that people with MS were more likely to harbor and show a greater abundance of epsilon ...
Ma, Yinghua, Sannino, David, Linden, Jennifer R, Haigh, Sylvia, Zhao, Baohua, Grigg, John B, Zumbo, Paul, Dündar, Friederike, Butler, Daniel J, Profaci, Caterina P, Telesford, Kiel M, Winokur, Paige N, Rumah, Kareem R, Gauthier, Susan A, Fischetti, Vincent A, McClane, Bruce A, Uzal, Francisco A, Zexter, Lily, Mazzucco, Michael, Rudick, Richard, Danko, David, Balmuth, Evan, Nealon, Nancy, Perumal, Jai, Kaunzner, Ulrike W, Brito, Ilana L, Chen, Zhengming, Xiang, Jenny Z, Betel, Doron, Daneman, Richard, Sonnenberg, Gregory F, Mason, Christopher E, Vartanian, Timothy   +32 more
openaire   +2 more sources