Results 181 to 190 of about 26,317 (223)
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Stimulus-Evoked Modulation of Sensorimotor Pyramidal Neuron EPSPs
Journal of Neurophysiology, 2002Sensory cortical neurons display substantial receptive field dynamics during and after persistent sensory drive. Because a cell's response properties are determined by the inputs it receives, receptive field dynamics are likely to involve changes in the relative efficacy of different inputs to the cell. To test this hypothesis, we have investigated if
Adam, Kohn +3 more
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The Effects of Anticonvulsant Drugs on NMDA-EPSP, AMPA-EPSP, and GABA-IPSP in the Rat Hippocampus
Brain Research Bulletin, 1997The effects of phenobarbital, phenytoin, and valproic acid on pharmacologically isolated NMDA-EPSP, AMPA-EPSP, and GABA-IPSPs were examined in rat hippocampal slices. Phenobarbital (0.05 mg/ml) had no effect on the NMDA-EPSP, but decreased the slope of the AMPA-EPSP by 13.4% and facilitated the GABA-IPSP slope by 77.12%.
G Y, Ko, L M, Brown-Croyts, T J, Teyler
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Monosynaptic EPSPs in primate lumbar motoneurons
Journal of Neurophysiology, 19931. Homonymous and heteronymous monosynaptic composite excitatory postsynaptic potentials (EPSPs) were evaluated by intracellular recordings from 89 motoneurons innervating triceps surae (n = 59) and more distal (n = 30) muscles in 14 pentobarbital-anesthetized monkeys (Macaca nemestrina). 2. Homonymous EPSPs were found in all motoneurons tested.
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Further results with the ‘uniquantal EPSP’ hypothesis
Hearing Research, 1997The hypothesis of Geisler (Brain Res. 212 (1981) 198-201), in which the different spontaneous-rate classes of primary auditory neurons were accounted for by the different sizes of uniquantal EPSPs relative to the gap between resting membrane and threshold potentials, was represented with an expanded model which included relative refractory effects. The
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Journal of Biomolecular Structure and Dynamics, 2013
Although the proposed mechanisms are reasonable, there are still many questions about the 5-enolpyruvyl shikimate-3-phosphate (EPSP) synthase mechanism that are difficult to answer by experimental means alone. EPSP synthase is a key enzyme in the shikimic acid pathway, which is found only in plants and some micro-organisms and is also molecular target ...
Melissa Soares, Caetano +3 more
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Although the proposed mechanisms are reasonable, there are still many questions about the 5-enolpyruvyl shikimate-3-phosphate (EPSP) synthase mechanism that are difficult to answer by experimental means alone. EPSP synthase is a key enzyme in the shikimic acid pathway, which is found only in plants and some micro-organisms and is also molecular target ...
Melissa Soares, Caetano +3 more
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A New Echeloned Poisson Series Processor (EPSP)
Celestial Mechanics and Dynamical Astronomy, 2001zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Neuroscience Letters, 1998
In slices kept at 33 degrees C, N-methyl-D-aspartate (NMDA) receptor- and (+/-)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor-mediated field excitatory post-synaptic potentials (EPSPs) were pharmacologically isolated in CA1.
R, Nader, R, Forghani, K, Krnjević
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In slices kept at 33 degrees C, N-methyl-D-aspartate (NMDA) receptor- and (+/-)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor-mediated field excitatory post-synaptic potentials (EPSPs) were pharmacologically isolated in CA1.
R, Nader, R, Forghani, K, Krnjević
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Journal of Neurophysiology, 1996
1. We reexamined the important areas of conflict in (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid [(1S,3R)-ACPD]-induced potentiation of the field excitatory postsynaptic potential (EPSP) and, for the first time, investigated the role of mGluRs in EPSP-spike (E-S) coupling. 2. (1S,3R)-ACPD (10 microM) bath applied for 20 min consistently induced a
N A, Breakwell, M J, Rowan, R, Anwyl
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1. We reexamined the important areas of conflict in (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid [(1S,3R)-ACPD]-induced potentiation of the field excitatory postsynaptic potential (EPSP) and, for the first time, investigated the role of mGluRs in EPSP-spike (E-S) coupling. 2. (1S,3R)-ACPD (10 microM) bath applied for 20 min consistently induced a
N A, Breakwell, M J, Rowan, R, Anwyl
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Journal of the American Chemical Society, 1992
A number of analogues of the intermediate and product of the enzyme EPSP synthase are described. Inert analogues that show high affinity for the enzyme from Petunia hybrida are produced by replacing the labile ketal phosphate moiety of this intermediate with a phosphonate or by stabilizing the ketal phosphate against ionization through introduction of ...
David G. Alberg +4 more
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A number of analogues of the intermediate and product of the enzyme EPSP synthase are described. Inert analogues that show high affinity for the enzyme from Petunia hybrida are produced by replacing the labile ketal phosphate moiety of this intermediate with a phosphonate or by stabilizing the ketal phosphate against ionization through introduction of ...
David G. Alberg +4 more
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Ia reflexes and EPSPs in human soleus motor neurones
Experimental Brain Research, 1989The reflex responses of single motor units in the soleus muscle to electrical stimulation of the tibial nerve were recorded in human volunteers. A feature of the experiments was the stimulation paradigm used. In order to control the peri-stimulus firing rate, a computer triggered the stimulus isolator only when 2 interspike intervals of specified ...
T S, Miles, K S, Türker, T H, Le
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