Results 71 to 80 of about 16,436 (224)

A Modified phosphate-carrier protein theory is proposed as a non-target site mechanism For glyphosate resistance in weeds Teoria das proteínas carregadoras fosfato modificadas proposta como mecanismo de resistência ao herbicida glyphosate em plantas daninhas

Planta Daninha, 2010
Glyphosate is an herbicide that inhibits the enzyme 5-enolpyruvyl-shikimate-3-phosphate synthase (EPSPs) (EC 2.5.1.19). EPSPs is the sixth enzyme of the shikimate pathway, by which plants synthesize the aromatic amino acids phenylalanine, tyrosine, and ...
A.C. Roso, R.A. Vidal
doaj   +1 more source

Voltage-Gated Sodium Channels Shape Subthreshold EPSPs in Layer 5 Pyramidal Neurons From Rat Prefrontal Cortex

, 2001
The role of voltage-dependent channels in shaping subthreshold excitatory postsynaptic potentials (EPSPs) in neocortical layer 5 pyramidal neurons from rat medial prefrontal cortex (PFC) was investigated using patch-clamp recordings from visually ...
German Barrionuevo, Guillermo González-Burgos   +1 more
core   +1 more source

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency, Tao Cui, Yimei Cai, Chloe Lok, Rachel E. Nokku, Ruoxian Huang, Grace L. Chu, Yumeng Xie, Saleem W. Abu‐Tayeh, Kaikai He, Chengjie Qiu, Junyi Wang, Paxton M. Paganelli, Ting Wang, Gabrielle Williams, Sreejith Nair, Huadong Pei, Dion K. Dickman, Stefano Vicini, Tingting Wang   +19 more
wiley   +1 more source

EPSP Amplification and the Precision of Spike Timing in Hippocampal Neurons [PDF]

Neuron, 2000
The temporal precision with which EPSPs initiate action potentials in postsynaptic cells determines how activity spreads in neuronal networks. We found that small EPSPs evoked from just subthreshold potentials initiated firing with short latencies in most CA1 hippocampal inhibitory cells, while action potential timing in pyramidal cells was more ...
Fricker, Desdemona, Miles, Richard
openaire   +2 more sources

Mild Focal Cooling Decouples Dendrites to Reconfigure Cortical Output

Advanced Science, Volume 13, Issue 34, 19 June 2026.
Mild cooling of the cortical surface selectively modulates apical dendritic excitability, plasticity, and somato‐dendritic coupling, while uncoupling these effects from basal dendrites, and reshapes apical‐driven responses in barrel cortex during whisker touch.
Meisam Habibi Matin, Shulan Xiao, Krishna Jayant   +2 more
wiley   +1 more source

Growth and Reproduction of Glyphosate-Resistant and Susceptible Populations of Kochia scoparia.

PLoS ONE, 2015
Evolution of glyphosate-resistant kochia is a threat to no-till wheat-fallow and glyphosate-resistant (GR) cropping systems of the US Great Plains. The EPSPS (5-enol-pyruvylshikimate-3-phosphate synthase) gene amplification confers glyphosate resistance ...
Vipan Kumar, Prashant Jha
doaj   +1 more source

Reduction in hippocampal cholinergic neurostimulating peptide enhances memory impairment in AppNL‐G‐F KI mice

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Whether cholinergic activity in the septohippocampal network affects cognitive dysfunction via hippocampal cholinergic neurostimulating peptide (HCNP) in Alzheimer's pathogenesis remains unclear. METHODS An Alzheimer's pathogenesis by mutation in amyloid‐beta precursor protein gene (AppNL‐G‐F) knock‐in (KI) and HCNP precursor ...
Yo Tsuda, Yuta Madokoro, Kengo Suzuki, Takuya Ooba, Toyohiro Sato, Yuto Uchida, Itsumi Nagai‐Arakawa, Takashi Saito, Hideaki Hara, Hideki Hida, Noriyuki Matsukawa   +10 more
wiley   +1 more source

Overview of wheat EPSPS homoeolog cloning and TILLING strategy and homoeolog-specific SNPS.

, 2021
A. The genomic intron-exon structure of the rice EPSPS is shown. Boxes indicate the eight exons and lines represent introns. The black arrows indicate the locations of PCR primers used to amplify fragments of wheat EPSPS homoeologs from wheat genomic DNA
Jos van Boxtel (11436900), Aaron Holm (11436885), Michael N. Steine (11436897), Daniel Facciotti (2830181), Jessica C. Mullenberg (11436891), Cate McGuire (11436903), Ann J. Slade (11436894), Charles P. Moehs (11436879), William J. Austill (11436882), Dayna Loeffler (11436888), Zhongjin Lu (10043306)   +10 more
core   +1 more source

Electrical advantages of dendritic spines.

PLoS ONE, 2012
Many neurons receive excitatory glutamatergic input almost exclusively onto dendritic spines. In the absence of spines, the amplitudes and kinetics of excitatory postsynaptic potentials (EPSPs) at the site of synaptic input are highly variable and depend
Allan T Gulledge, Nicholas T Carnevale, Greg J Stuart   +2 more
doaj   +1 more source

Channel Dysfunction as the Basis for Comorbidities in Multiple Sclerosis and Depression

Archiv der Pharmazie, Volume 359, Issue 6, June 2026.
Ion channel remodelling induced by neuroinflammation in multiple sclerosis alters neuronal excitability and immune signalling, creating shared molecular pathways that link multiple sclerosis pathology to depression and reveal novel pharmacological targets.
Nicole Rychlik, Kay Jüngling, Sven G. Meuth, Thomas Budde, Marta Méndez‐Couz   +4 more
wiley   +1 more source