Results 1 to 10 of about 1,782,146 (327)
Case Reports in Hematology, 2023 In this case, we describe the potential risk of developing an infectious complication leading to a secondary malignancy after a short course of immunotherapy. We report a patient who presented with Epstein–Barr virus (EBV) driven Hodgkin’s lymphoma after treatment with a short course of daratumumab along with pomalidomide and dexamethasone for relapsed
Moeen Mohammadi-Oroujeh +2 more
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Epstein–Barr virus–host cell interactions: an epigenetic dialog? [PDF]
Frontiers in Genetics, 2014 Epstein-Barr virus (EBV) is associated with diverse lymphoid and epithelial malignancies. Their molecular pathogenesis is accompanied by epigenetic alterations which are distinct for each of them. While lymphoblastoid cell lines (LCLs) derived from B cells transformed by EBV in vitro are characterized by a massive demethylation and euchromatinization ...
Niller, Hans Helmut +2 more
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Patch formation driven by stochastic effects of interaction between viruses and defective interfering particles [PDF]
PLoS Comput Biol 19(10), 2023, 2023 Defective interfering particles (DIPs) are virus-like particles that occur naturally during virus infections. These particles are defective, lacking essential genetic materials for replication, but they can interact with the wild-type virus and potentially be used as therapeutic agents.
arxiv +1 more source
Genetic factors leading to chronic Epstein-Barr virus infection and nasopharyngeal carcinoma in South East China: Study design, methods and feasibility [PDF]
Human Genomics, 2006 Nasopharyngeal carcinoma (NPC) is a complex disease caused by a combination of Epstein-Barr virus chronic infection, the environment and host genes in a multi-step process of carcinogenesis. The identity of genetic factors involved in the development of chronic Epstein-Barr virus infection and NPC remains elusive, however. Here, we describe a two-phase,
Guo, Xiu Chan +19 more
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Immunization With Fc-Based Recombinant Epstein–Barr Virus gp350 Elicits Potent Neutralizing Humoral Immune Response in a BALB/c Mice Model [PDF]
Frontiers in Immunology, 2018 Epstein-Barr virus (EBV) was the first human virus proved to be closely associated with tumor development, such as lymphoma, nasopharyngeal carcinoma, and EBV-associated gastric carcinoma. Despite many efforts to develop prophylactic vaccines against EBV infection and diseases, no candidates have succeeded in effectively blocking EBV infection in ...
Bingchun Zhao +13 more
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Detection of Epstein–Barr virus and Cytomegalovirus in Iraqi Acute Lymphoblastic Leukemia patients
AL-QADISIYAH MEDICAL JOURNAL, 2017 Objective : determination the percent of infection of EBV and CMV infections in Iraqi patient infected with ALL .Methods : the study have concentrated to determine the rate of EBV and CMV infections by detecting EBV and CMV antibodies in both the IgM and IgG classes of immunoglobulins by ELISA method and Indirect Immunofluorescence Test ( IIFT) as well
Mohammed A. Muhsin +2 more
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A rare case of Epstein–Barr virus‐related plasmacytoma involving maxillary sinus mucosa
Clinical Case Reports, 2017 Key Clinical MessageExtramedullary plasmacytomas, Epstein–Bar virus (EBV) associated, are rarely encountered and usually have a fairly good clinical outcome. EBV+ plasmacytoma may cause a diagnostic dilemma as it phenotypically resembles an aggressive plasmablastic lymphoma (PBL).
Julie D. Gibbs +4 more
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A Discrete-time Networked Competitive Bivirus SIS Model [PDF]
arXiv, 2023 The paper deals with the analysis of a discrete-time networked competitive bivirus susceptible-infected-susceptible (SIS) model. More specifically, we suppose that virus 1 and virus 2 are circulating in the population and are in competition with each other.
arxiv
Self-organized critical dynamics of RNA virus evolution [PDF]
arXiv, 2022 RNA virus (e.g., SARS-CoV-2) evolves in a complex manner. Studying RNA virus evolution is vital for understanding molecular evolution and medicine development. Scientists lack, however, general frameworks to characterize the dynamics of RNA virus evolution directly from empirical data and identify potential physical laws. To fill this gap, we present a
arxiv
Improving the identification of antigenic sites in the H1N1 Influenza virus through accounting for the experimental structure in a sparse hierarchical Bayesian model [PDF]
J. R. Stat. Soc. C (2019), 2017 Understanding how genetic changes allow emerging virus strains to escape the protection afforded by vaccination is vital for the maintenance of effective vaccines. In the current work, we use structural and phylogenetic differences between pairs of virus strains to identify important antigenic sites on the surface of the influenza A(H1N1) virus through
arxiv +1 more source