Epstein-Barr virus-related post-transplant lymphoproliferative disorders are recognized as a significant cause of morbidity and mortality in patients undergoing hematopoietic stem cell transplantation.
J. Styczyński+6 more
semanticscholar +1 more source
Prevention of Epstein-Barr virus-lymphoproliferative disease by molecular monitoring and preemptive rituximab in high-risk patients after allogeneic stem cell transplantation [PDF]
Recipients of a partially T-cell-depleted (TCD) allogeneic stem cell transplantation (allo-SCT) developing reactivation of Epstein-Barr virus (EBV) with quantified viral DNA levels exceeding 1000 genome equivalents/milliliter (geq/mL) are at high risk ...
Cornelissen, J.J. (Jan)+8 more
core +1 more source
Association Between Moraxella catarrhalis and Nodular Lymphocyte‐Predominant Hodgkin Lymphoma
ABSTRACT Nodular lymphocyte‐predominant Hodgkin Lymphoma (NLPHL) may be an antigen‐driven malignancy. Recent studies demonstrated that in NLPHL patients, lymphoma B‐cell receptor can bind proteins derived from Moraxella catarrhalis (MC) and Rothia mucilaginosa (RM). We examined whether MC and RM can be detected in NLPHL lymph nodes.
Izidore S. Lossos+7 more
wiley +1 more source
Mechanisms of B-Cell Oncogenesis Induced by Epstein-Barr Virus
Epstein-Barr virus (EBV) is a ubiquitous gammaherpesvirus which asymptomatically infects the majority of the world population. Under immunocompromised conditions, EBV can trigger human cancers of epithelial and lymphoid origin.
A. Saha, E. Robertson
semanticscholar +1 more source
Deciphering the role of Epstein-Barr virus in the pathogenesis of T and NK cell lymphoproliferations [PDF]
Epstein-Barr virus (EBV) is a highly successful herpesvirus, colonizing more than 90% of the adult human population worldwide, although it is also associated with various malignant diseases.
Fox, Christopher P+2 more
core +2 more sources
Grafts used to construct lung cancer animal models come from various sources, primarily cell lines, patient‐derived tumor tissues, and circulating tumor cells. Based on the sources of grafts and research objectives, lung cancer animal models can be categorized into several types: chemical‐induced models, orthotopic transplantation models, heterotopic ...
Zixuan Yang+7 more
wiley +1 more source
The Epstein Barr virus circRNAome
Our appreciation for the extent of Epstein Barr virus (EBV) transcriptome complexity continues to grow through findings of EBV encoded microRNAs, new long non-coding RNAs as well as the more recent discovery of over a hundred new polyadenylated lytic ...
Nathan Ungerleider+14 more
semanticscholar +1 more source
CD4+ T-cell responses to Epstein-Barr virus nuclear antigen EBNA1 in Chinese populations are highly focused on novel C-terminal domain-derived epitopes [PDF]
Epstein-Barr virus nuclear antigen EBNA1, the one viral protein uniformly expressed in nasopharyngeal carcinoma (NPC), represents a prime target for T-cell-based immunotherapy. However, little is known about the EBNA1 epitopes, particularly CD4 epitopes,
Chan, A. T. C.+8 more
core +1 more source
Cerebrospinal Fluid Metabolome in Central Nervous System Infections: A Study of Diagnostic Accuracy
Objective To assess the diagnostic accuracy of metabolites in cerebrospinal fluid (CSF) for central nervous system (CNS) infections. Methods Patients were derived from three prospective cohort studies in the Netherlands. All studies included adults suspected of a CNS infection who underwent a diagnostic lumbar puncture.
Steven L. Staal+7 more
wiley +1 more source
Epstein–Barr Virus and Hemophagocytic Lymphohistiocytosis
Epstein–Barr virus (EBV) is a ubiquitous virus that infects nearly all people worldwide without serious sequela. However, for patients who have genetic diseases which predispose them to the development of hemophagocytic lymphohistiocytosis (HLH), EBV ...
R. Marsh
semanticscholar +1 more source