Results 81 to 90 of about 1,167,902 (208)

Epstein-Barr virus-associated lymphomas

, 2004
Following Epstein and colleagues' ground-breaking discovery of Epstein-Barr virus by electron microscopy of Burkitt's lymphoma cell lines, there came the observation that Epstein-Barr virus induces immortalization of B cells in vitro. Thus, initial hopes
D Brooke Johnson, Johnson, Devin Brooke, Cadeddu, Jeffrey A., Jeffrey A Cadeddu, Gandhi, M. K.   +4 more
core   +1 more source

A Tripartite Model for EBV‐Driven Multiple Sclerosis: B Cell Survival, Altered Self‐Presentation, and HLA‐DR15‐Restricted T Cell Cross‐Reactivity

iNew Medicine, EarlyView.
ABSTRACT This commentary integrates findings from three recent Cell reports to establish a unified mechanistic model of multiple sclerosis (MS) driven by the interplay between Epstein‐Barr virus (EBV) and the HLA‐DR15 genotype. EBV promotes CNS autoimmunity through three distinct but intersecting mechanisms.
Fang Zhu, Arnaud John Kombe Kombe, Tengchuan Jin   +2 more
wiley   +1 more source

Epstein-Barr Virus Encephalitis: A Case Report [PDF]

, 2015
How to Cite This Article: Hashemian S, Ashrafzadeh F, Akhondian J, Beiraghi Toosi M. Epstein-Barr Virus Encephalitis: A Case Report. Iran J Child Neurol. 2015 Winter;9(1):107-110.
AKHONDIAN, Javad, HASHEMIAN, Somayh, ASHRAFZADEH*, Farah, BEIRAGHI TOOSI, Mehran   +3 more
core   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

Aphasic status epilepticus due to Epstein–Barr virus meningoencephalitis – A clinical vignette

Epileptic Disorders, EarlyView.
Gemma Bassani, Tobias Moser, Lukas Machegger, Fabio Rossini, Georg Pilz, Eugen Trinka, Giorgi Kuchukhidze   +6 more
wiley   +1 more source

Molecular Functions and Drug Prediction of MMP1 and TGFBR2 in Nasopharyngeal Carcinoma

Journal of Clinical Laboratory Analysis, EarlyView.
MMP1 and TGFBR2 were validated by machine learning and external datasets as the candidate genes. Dexamethasone showed strong binding affinity to MMP1 (−7.72 kcal/mol) and TGFBR2 (−7.27 kcal/mol) in docking studies. Knockdown of MMP1 repressed the malignant phenotypes of NPC cells.
Feng Wang, Binbin Ge, Ming Li, Xiaochun Xia, Fuming Zhang, Pengqin Xu   +5 more
wiley   +1 more source

Bilateral acute macular neuroretinopathy after Epstein-Barr virus encephalitis

American Journal of Ophthalmology Case Reports
Purpose: To report a case of a 11-year-old girl, who developed a bilateral acute macular neuroretinopathy (AMN) after Epstein-Barr virus (EBV) encephalitis.
Daniella Socci da Costa, Raul N.G. Vianna, Remo Turchetti Moraes, Gilberto dos Passos Junior, Aluisio Rosa Gameiro Filho   +4 more
doaj   +1 more source

Luteolin inhibits Epstein-Barr virus lytic reactivation by repressing the promoter activities of immediate-early genes

, 2017
The lytic reactivation of Epstein-Barr virus (EBV) has been reported to be strongly associated with several human diseases, including nasopharyngeal carcinoma (NPC). Inhibition of the EBV lytic cycle has been shown to be of great benefit in the treatment
Wu, Chung-Chun;Fang, Chih-Yeu;Hsu, Hui-Yu;Chen, Yen-Ju;Chou, Sheng-Ping;Huang, Sheng-Yen;Cheng, Yu-Jhen;Lin, Su-Fang;Chang, Yao;Tsai, Ching-Hwa;Chen, Jen-Yang, 陳振陽;蔡錦華   +1 more
core   +1 more source

Pediatric Systemic Lupus Erythematosus Complicated by Acute EBV and CMV Co‐infection

Journal of Clinical Laboratory Analysis, EarlyView.
This case report describes a 10‐year‐old girl with new‐onset pediatric SLE who presented with malar rash, fever, and arthritis following sun exposure, alongside serological evidence of acute Epstein–Barr virus (EBV) and cytomegalovirus (CMV) co‐infection.
Anning Chen, Gengchun Ji, Ziping Lan, Ping Li, Jianwei Wang, Le Zhang, Chaojun Hu, Shulan Zhang   +7 more
wiley   +1 more source

Epstein-Barr virus infection as a predisposing factor for multiple sclerosis. An update from molecular biology, immunology and epidemiology

Revista de la Facultad de Medicina, 2019
Introduction: Epstein-Barr virus is an infectious agent used to immortalize and induce polyclonal activation of B cells. It has been widely described that this virus produces changes in the cells it infects and in the immune response, and stimulates the
David López-Valencia, Ángela Medina-Ortega, Diego Fernando Hoyos-Samboní, Jhan Sebastián Saavedra-Torres, Carolina Salguero   +4 more
doaj   +1 more source