Results 101 to 110 of about 1,167,902 (208)

Microbiota Transplantation Effectively Treats Immune Checkpoint Inhibitor‐Associated Colitis: A Multi‐Center, Retrospective Case Series

open access: yesMicrobiota Medicine Research, EarlyView.
ABSTRACT Background Immune‐mediated colitis is an adverse effect of therapy with immune checkpoint inhibitors (ICIs). This study aims to evaluate the efficacy and safety of washed microbiota transplantation (WMT) in patients with ICI‐associated colitis.
Mengyu Huang   +7 more
wiley   +1 more source

Long‐term outcomes of haploidentical hematopoietic stem cell transplantation with antithymocyte globulin–based myeloablative conditioning in pediatric refractory or relapsed non‐Hodgkin lymphoma

open access: yesPediatric Investigation, EarlyView.
Single‐center retrospective data showed that ATG‐based myeloablative haploidentical hematopoietic stem cell transplantation provides durable remission and favorable long‐term survival in children with refractory/relapsed non‐Hodgkin lymphoma, achieving high engraftment rates, low relapse incidence, and acceptable toxicity.
Chenguang Jia   +12 more
wiley   +1 more source

Analysis of the presence of Epstein-Barr virus in Hodgkin\'s lymphoma in Iranian children by EBER in situ hybridization

open access: yesفصلنامه دانشگاه علوم پزشکی جهرم, 2014
Background & Objectives: Epstein-Barr virus (EBV) is a tumorigenic herpes virus and belong to DNA viruses that infects and persists in B lymphocytes in the majority of humans and also is associated with a portion of cases of Hodgkin lymphoma (HL).
leila mozafari   +3 more
doaj  

Dynamic early biomarkers predict outcomes in pediatric Epstein–Barr virus‐associated hemophagocytic lymphohistiocytosis

open access: yesPediatric Investigation, EarlyView.
This study elucidates the critical pathogenic mechanisms of pediatric Epstein–Barr virus‐associated hemophagocytic lymphohistiocytosis (EBV‐HLH), where EBV infection triggers a cytokine storm leading to immune cell hyperactivation and tissue damage. Dynamic plasma biomarkers (EBV‐DNA, ferritin, and interferon‐γ) effectively predict treatment response ...
Feifei Liu   +9 more
wiley   +1 more source

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

open access: yesPediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source

The Epstein-Barr Virus Replication and Transcription Activator, Rta/Brlf1 , Induces Cellular Senescence in Epithelial Cells

open access: yes, 2010
Epstein-Barr Virus (EBV) replication and transcription activator (Rta/ BRLF1) is an immediate-early transcription factor that controls the conversion of the latent viral genome into one undergoing lytic replication.
陳振陽;林素芳   +1 more
core   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

open access: yesPhytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko   +3 more
wiley   +1 more source

Timing of Epstein-Barr Virus Acquisition and the Course of Posttransplantation Lymphoproliferative Disorder in Children

open access: yes, 2011
Background. To investigate the clinical course and risk factors of Epstein-Barr virus (EBV)-associated posttransplantation lymphoproliferative disorder (PTLD) after liver transplantation (LT) among children in Taiwan where children acquired EBV infection
吳嘉峰;何明志;倪衍玄;陳慧玲;呂俊毅;許宏遠;李伯皇;張美惠   +1 more
core   +1 more source

Hidroa vacciniforme y el desorden linfoproliferativo hidroa vacciniforme-like reporte de caso y revisión de la literatura

open access: yesRevista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica
Introducción: La hidroa vacciniforme es una fotodermatosis infrecuente crónica que puede relacionarse con la infección por el virus del Epstein-Barr. También, se asociada a deformidad progresiva y al riesgo de desarrollo de linfomas cutáneos. Método:
Ana María Gutiérrez-Delgadillo   +6 more
doaj   +1 more source

BARF1 AS A NEW THERAPEUTIC TARGET FOR EBV-ASSOCIATED MALIGNANCIES.

open access: yes, 2010
While Epstein-Barr virus-specific cytotoxic T lymphocytes (EBV-CTLs) have been used successfully for the prophylaxis and treatment of the highly immunogenic post-transplant lymphoproliferative disorders, the clinical experience for other EBV-associated ...
Martorelli, Debora
core  

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