Results 191 to 200 of about 201,604 (251)

Case Report: A rare case of Epstein-Barr virus mucocutaneous ulcers occurring in the eyeball and literature review. [PDF]

open access: yesFront Med (Lausanne)
Ke X   +9 more
europepmc   +1 more source

Systematic Proteomic Characterization of EV‐A71‐Infected Mice Identifies Dynamic Molecular Changes and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Time‐resolved multi‐omics of EV‐A71‐infected BALB/c mice uncovered dynamic host responses, revealing rapid neutrophil extracellular traps (NETs) activation as a key event. Screened drugs (kinase inhibitors) suppressed viral replication in vitro and in vivo, suggesting the promise of targeting host phosphorylation networks as a viable antiviral strategy.
Wanjun Peng   +11 more
wiley   +1 more source

Liquid–Liquid Phase Separation in Viral Infection and Immunology

open access: yesMedComm, Volume 7, Issue 4, April 2026.
LLPS organizes viral replication and antiviral immunity. Viruses hijack LLPS to form replication factories and evade immune sensors, while hosts assemble LLPS‐driven signaling hubs (e.g., MAVS, RIG‐I, and SGs) to amplify interferon responses. Targeting these condensate interfaces offers novel therapeutic strategies against infectious diseases ...
Jiuzhi Xu   +5 more
wiley   +1 more source

Circulating Microbial Metabolites Predict Tumor Relapse and Chemotherapy Efficacy in Nasopharyngeal Carcinoma

open access: yesMedComm, Volume 7, Issue 4, April 2026.
ABSTRACT The value of microbial metabolites in prognosis and treatment response prediction in patients with nasopharyngeal carcinoma (NPC) remains unclear. Here, through the untargeted metabolomic analysis of plasma in 48 paired NPC patients with or without tumor relapse, we identified distinct circulating metabolite atlases between NPC patients with ...
Jun‐Yan Li   +16 more
wiley   +1 more source

Immunocompromised Status Definition in Observational Studies Using Electronic Health Records: A Scoping Review and a Proposal for a Phenotype Identification Algorithm

open access: yesPharmacoepidemiology and Drug Safety, Volume 35, Issue 4, April 2026.
ABSTRACT Immunocompromised individuals experience an impaired immune function due to conditions that might be either congenital or acquired over the course of their lives. Epidemiological studies often rely on clinical definitions which, in some cases, benefit from being translated into machine‐readable algorithms for application to electronic health ...
Judit Riera‐Arnau   +62 more
wiley   +1 more source

Investigation of genetic and lifestyle risk factors associated with Epstein-Barr virus reactivation in the Thai population. [PDF]

open access: yesBiomed Rep
Bamrungthai J   +12 more
europepmc   +1 more source

Development of a Donor‐Based Predictive Model for Pancreas Non‐Utilization Among Deceased Donor Transplants in the US

open access: yesClinical Transplantation, Volume 40, Issue 4, April 2026.
ABSTRACT Background Pancreas non‐utilization affects 25%–30% of deceased donor offers in the US. The European‐derived Pre‐Procurement Pancreas Suitability Score (P‐PASS) has performed inconsistently, is not validated in North America, and requires less accessible inputs, highlighting need for a robust prediction tool for non‐utilization.
Christie Rampersad   +4 more
wiley   +1 more source

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