Results 41 to 50 of about 201,604 (251)

Identification of type A and B isolates of Epstein-Barr virus by polymerase chain reaction [PDF]

, 1990
A method is described for the identification of type A and type B isolates of Epstein-Barr virus (EBV) by means of the polymerase chain reaction. The use of three pairs of primers specific for genomic sequences coding for the two forms of EBV nuclear ...
Alliger, P., Jilg, Wolfgang, Siegert, E., Wolf, Hans J.   +3 more
core   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Epstein-Barr virus nuclear antigen 3A protein regulates CDKN2B transcription via interaction with MIZ-1 [PDF]

, 2014
The Epstein-Barr virus (EBV) nuclear antigen 3 family of protein is critical for the EBV-induced primary B-cell growth transformation process. Using a yeast two-hybrid screen we identified 22 novel cellular partners of the EBNA3s. Most importantly, among
Bazot, Q, Deschamps, T, Gruffat, H, Harth-Hertle, ML, Kempkes, B, Leblanc, P, Lotteau, V, Manet, E, Rabourdin-Combe, C, Siouda, M, Tafforeau, L, Tommasino, M   +11 more
core   +6 more sources

PD‐L1‐Binding Antigen Presenters: Redirecting Vaccine‐Induced Antibodies for Cancer Immunotherapy

Advanced Science, EarlyView.
The PBAP‐gE complex anchors gE antigen to PD‐L1 on tumor cells. Vaccine‐induced anti‐gE antibodies simultaneously engage FcγRIIIa on NK cells and tumor‐bound PBAP‐gE, triggering NK cell activation and antibody‐dependent cellular cytotoxicity, thereby selectively eliminating PD‐L1–expressing tumor cells.
Huixin Gao, Lijuan Lu, Xiaoxiao Xiong, Yi Li, Donghui Hu, Duo Zhang, Zhiwei Feng, Cong Liu, Nannan Liu, Xiaoli Li, Jizhou Tan, Ting Liu, Ling Peng, Lu Lu, Huiyi Feng, Yan Zhong, Guisen Tan, Zhicheng Zhang, Liqin Huang, Chao Su, Ying Xue, Shuo Song, Wenxia Fan, Wei Wang, Fan Zou   +24 more
wiley   +1 more source

A new therapy in Epstein-Barr virus-associated lymphoproliferative disease: a case report and a revision of the literature

Italian Journal of Pediatrics, 2019
Background Systemic chronic active Epstein-Barr virus infection is an extremely rare childhood disease. Since chronic active Epstein-Barr virus infection can trigger the onset of Epstein-Barr virus-associated lymphoproliferative disease.
Lingling Xu, Hongjun Ba, Hongrong Lin, Liangying Zhong, Suping Li, Wen Tang, Zhiyong Ke, Ziyin Ye   +7 more
doaj   +1 more source

Morphofunctional state of the gastric mucosa in children with chronic gastritis and the persistence of Epstein-Barr virus

Детские инфекции (Москва), 2022
The aim is to establish the effect of the persistence of the Epstein-Barr virus on the morphofunctional state of the gastric mucosa in chronic gastritis in children. Methods. 324 children aged 6—16 years with chronic gastritis were examined.
E. P. Sitnikova, E. M. Spivak, O. M. Manyakina   +2 more
doaj   +1 more source

Immunosenescence and lymphomagenesis [PDF]

, 2018
One of the most important determinants of aging-related changes is a complex biological process emerged recently and called \u201cimmunosenescence\u201d.
A Beheshti, A Engert, A Grignolio, A Nicolae, A Rosenwald, A Tucci, AM Evens, BB Hart, BF Skinnider, BK Edwards, BO Nilsson, C Caruso, C Castelo-Branco, C Falandry, C Falandry, C Franceschi, C Franceschi, C Kenis, C Sarkozy, C Sarkozy, C Thieblemont, CC Porter, CM Koebel, D Aldinucci, D Hanahan, D Zhou, DB Palmer, DM Parkin, DP Shanley, E Campo, E Cesarman, E Zucca, F Suarez, FL Erdkamp, FT Hakim, G Accardi, G Genovese, G Lenz, G Pawelec, GM Clifford, H Wildiers, I Schwering, J Campisi, J Wang, JJ Castillo, L Malaguarnera, LM Morton, M Goto, M Martelli, M Weltevrede, Marco Santoro, Mariasanta Napolitano, Melania Carlisi, N Asano, NS Wong, O Balague Ponz, P Skrabek, PJ Linton, PR Taylor, PR Walker, R Kim, RF Jarrett, RL Bowman, RR Montgomery, S Dubois, S Joos, S Mareschal, S Mathas, S Mathas, S Puvvada, Salvatrice Mancuso, Sergio Siragusa, SH Swerdlow, Simona Raso, SJ Morrison, SJ Proctor, SL Glaser, SR Gordon, SR Hadrup, T Finkel, T Fulop, T Fulop, T Fülöp, T Fülöp, T Fülöp, T Ishida, T Wada, W Drew, W Klapper, Z Ju, Z Song   +90 more
core   +1 more source

NIPAL1 Drives a Metabolic‐Epigenetic Feedback Loop to Promote Lactate‐Mediated Immune Evasion in Esophageal Cancer

Advanced Science, EarlyView.
The study identifies a NIPAL1‐driven metabolic‐epigenetic circuit in esophageal squamous cell carcinoma that promotes glycolysis, lactate accumulation, and H3K18 histone lactylation, forming a self‐sustaining loop that suppresses CD8+ T cell immunity.
Ri‐Xin Chen, Xiao‐Dan Ma, Shui‐Dan Xu, Ao‐Tian Mo, Min‐Hua Deng, Jun‐Han Wu, Wei‐Tao Zhuang, Jin‐Ling Duan, Shu‐Huan Xie, Jin‐Long Lin, Peng Lin, Ji‐Ming Tang, Hai‐Yu Zhou, Xiao‐Song Ben, Gui‐Bin Qiao, Dan Xie   +15 more
wiley   +1 more source

Violaceous nodules in an HIV-positive man [PDF]

, 2020
Plasmablastic lymphoma (PBL) is a rare and aggressive malignancy associated with immunosuppression and the oncogenic effects of the Epstein-Barr virus (EBV).
Dominguez, Arturo R, Nguyen, Khang D, Scott, Brian L   +2 more
core  

Phenotypic Diversity and Outcomes in Pediatric NMDA Receptor Encephalitis: A 15‐Year Retrospective Study from the Largest Children's Hospital in the United States

Advanced Science, EarlyView.
ABSTRACT Anti‐NMDAR encephalitis (NMDARE) is an autoantibody‐mediated disorder characterized by seizures, movement disorders, neurocognitive deficits, and psychosis, but the complete phenotypic heterogeneity, and outcomes are incompletely understood in children.
Alexander J. Sandweiss, Timothy Erickson, Yike Jiang, Varun Kannan, Jonathan M. Yarimi, Kristen S. Fisher, Nikita Shukla, Tim Lotze, Eyal Muscal, Kristy O. Murray   +9 more
wiley   +1 more source