Results 81 to 90 of about 1,328,799 (258)

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Epstein-Barr Virus (EBV) DNA in Sera of Patients with Primary EBV Infection

Journal of Clinical Microbiology, 2001
ABSTRACT Detection of Epstein-Barr Virus (EBV) DNA by PCR in serum had a sensitivity of 80%, a specificity of 94%, and positive and negative predictive values of 95 and 79%, respectively, for the diagnosis of primary EBV infection. We suggest that this is a useful addition to the panel of tests used for this purpose.
Chan, KH, Peiris, JSM, Ng, MH, Seto, WH
openaire   +4 more sources

A Tripartite Model for EBV‐Driven Multiple Sclerosis: B Cell Survival, Altered Self‐Presentation, and HLA‐DR15‐Restricted T Cell Cross‐Reactivity

iNew Medicine, EarlyView.
ABSTRACT This commentary integrates findings from three recent Cell reports to establish a unified mechanistic model of multiple sclerosis (MS) driven by the interplay between Epstein‐Barr virus (EBV) and the HLA‐DR15 genotype. EBV promotes CNS autoimmunity through three distinct but intersecting mechanisms.
Fang Zhu, Arnaud John Kombe Kombe, Tengchuan Jin   +2 more
wiley   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

Analysis of the presence of Epstein-Barr virus in Hodgkin\'s lymphoma in Iranian children by EBER in situ hybridization

فصلنامه دانشگاه علوم پزشکی جهرم, 2014
Background & Objectives: Epstein-Barr virus (EBV) is a tumorigenic herpes virus and belong to DNA viruses that infects and persists in B lymphocytes in the majority of humans and also is associated with a portion of cases of Hodgkin lymphoma (HL).
leila mozafari, sohrab najafipour, mohammad- hassan meshkibaf, ali moravej   +3 more
doaj  

Discrepant Urinary Findings Between Dipstick Protein and Sulfosalicylic Acid Test in a Patient With Hyaline Casts: A Case Report

Journal of Clinical Laboratory Analysis, EarlyView.
In this post‐transplant patient, increased hyaline casts with negative dipstick protein but positive SSA testing occurred during evolving acute kidney injury and resolved with renal recovery. This discordant urinalysis pattern may warrant confirmatory protein testing and correlation with serial renal function in patients at high risk of AKI.
Yifei Jia, Binquan Chu, Fengjun Chen, Xiangyu Zhu, Chen Hang, Xiaoling Yu, Jinpiao Lin   +6 more
wiley   +1 more source

Overview of EBV-Associated T/NK-Cell Lymphoproliferative Diseases

Frontiers in Pediatrics, 2019
Epstein-Barr virus-associated T/natural killer-cell lymphoproliferative diseases (EBV-T/NK-LPDs) are a group of rare diseases resulting from ectopic infection of T or natural killer (NK) lymphocytes with Epstein-Barr virus (EBV).
Hiroshi Kimura, Shigeyoshi Fujiwara, Shigeyoshi Fujiwara   +2 more
doaj   +1 more source

Pancreas–Intestine Composite Transplantation for Simultaneous Loss of Pancreatic and Intestinal Function (With Video)

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Pancreas–intestine composite transplantation (PITx) is a therapeutic option for patients with irreversible loss of both pancreatic and intestinal function. We report a case of PITx in a 16‐year‐old male who developed fulminant Type 1 diabetes mellitus complicated by non‐occlusive mesenteric ischemia, resulting in extensive intestinal necrosis.
Kei Yamane, Takashi Ito, Takayuki Anazawa, Junji Fujikura, Makoto Okabe, Satoshi Ishida, Koki Kurahashi, Masaaki Hirata, Hiroshi Kawamoto, Hiroto Nishino, Asahi Sato, Tomoaki Yoh, Hidenobu Kojima, Shinya Okumura, Takahiro Nishio, Daisuke Ueda, Hirofumi Hirao, Yuki Masano, Shoichi Kageyama, Katsunori Sakamoto, Satoshi Ogiso, Kazuyuki Nagai, Yoichiro Uchida, Takamichi Ishii, Etsuro Hatano   +24 more
wiley   +1 more source

MRI‐Derived Lymph Node Characteristics for Risk Stratification of Distant Metastasis in Locoregionally Advanced Nasopharyngeal Carcinoma

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background MRI‐derived nodal features may improve prognostication beyond TNM staging, but distant‐metastasis risk models remain limited. Purpose To develop and internally validate an MRI model for distant metastasis prediction in locoregionally advanced nasopharyngeal carcinoma (LA‐NPC). Study Type Retrospective.
Jing Wang, Yuxing Yu, Honghong Zhang, Haosheng Zhang, Jianxian Chen, Jiajia Zheng, Qisi Zhang, Hengyu Guo, Lanxin Lin, Yubin Hu, Sufang Qiu   +10 more
wiley   +1 more source

Association of Epstein-Barr virus and Hodgkin’s disease [PDF]

Acta Medica Iranica, 2003
We have analyzed paraffin sections from 55 patients with histologically confirmed Hodgkin’s disease (HD) for the presence of Epstein-Barr virus (EBV) markers using in situ hybridization to detect the EBV-encoded RNAs (EBERs) and immunohistochemistry to ...
Najafipour S, Mokhtari Azad T, Kousari F, Mahmoodi M, Murray PG, Nategh R   +5 more
doaj   +2 more sources