While several oncogenic pathogens cause site‐specific cancers, uncertainties remain about many other chronic infections and combined pathogen effects, especially in non‐Western populations. Using a large case–cohort study nested within the China Kadoorie Biobank, the authors found that co‐infection was common, with a mean of 10 pathogens per individual.
Ling Yang +212 more
wiley +1 more source
Exploring the Link Between Genetic Predictors of Systemic Lupus Erythematosus and Epstein-Barr Virus Infections. [PDF]
Piao Y +6 more
europepmc +1 more source
Radiotherapy‐Induced Otitis Media With Effusion in Nasopharyngeal Carcinoma: A Meta‐Analysis
This meta‐analysis of eight studies comprising 582 NPC patients provides the first quantitative synthesis of radiotherapy‐induced otitis media with effusion (OME), demonstrating a significant overall risk difference of 0.18 (95% CI: −0.06 to 0.42, p < 0.0001) in OME naive ears.
Nevin Yi Meng Chua +3 more
wiley +1 more source
Oxysterols in Cancer: From Biosynthesis and Pathophysiology to Targeted Therapeutics
Mechanisms by which oxysterol targeting may enhance immunotherapy efficacy. This figure illustrates potential metabolic interventions that may improve antitumor immunity by modulating oxysterol related pathways. CH25H modulation may reduce 25‐HC accumulation, promote the conversion of cold tumors into hot tumors, and increase T cell infiltration and PD‐
Haili Shang, Yongsheng Li
wiley +1 more source
Human cytomegalovirus and Epstein-Barr virus infections increase the risk of death in patients with head and neck cancers receiving radiotherapy or radiochemotherapy. [PDF]
Kiprian D +3 more
europepmc +1 more source
Targeting progressive multiple sclerosis: Toward mechanism‐informed precision medicine
Abstract Multiple sclerosis has undergone a therapeutic revolution over the past three decades. Randomized clinical trials and real‐world data demonstrate that modern disease‐modifying therapies substantially reduce relapse rates and acute inflammatory activity detected by magnetic resonance imaging (MRI).
Fredrik Piehl +3 more
wiley +1 more source
Identifying Safeguards Disabled by Epstein-Barr Virus Infections in Genomes From Patients With Breast Cancer: Chromosomal Bioinformatics Analysis. [PDF]
Friedenson B.
europepmc +1 more source
Human cytomegalovirus and Epstein-Barr virus infections, risk factors, and their influence on the liver function of patients with acute-on-chronic liver failure. [PDF]
Hu J +7 more
europepmc +1 more source
The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli +3 more
wiley +1 more source
Manufacturing and clinical applications of non‐CAR‐T immune effector cells
Transfusion, EarlyView.
Thane Kubik +2 more
wiley +1 more source

