Results 131 to 140 of about 73,157 (247)

Increased Risk of Environmental and Endemic Infectious Diseases in Sjögren's Disease: A Retrospective Analysis (2015–2023)

open access: yesACR Open Rheumatology, Volume 8, Issue 8, August 2026.
Objective Sjögren's disease (SjD) is a chronic autoimmune disease with a complex etiology, where pathogens may influence disease development or progression. Although SjD is not communicable, environmental and endemic pathogen exposures may influence its onset or progression.
Swetha K. Shankar   +3 more
wiley   +1 more source

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

open access: yesAdvanced Science, Volume 13, Issue 44, 7 August 2026.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth   +10 more
wiley   +1 more source

Atypical Clinical Course of Griscelli Syndrome Type 2 With Primarily Neurologic Presentation and Adult‐Onset in a 46‐Year‐Old Male

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1850-1855, August 2026.
ABSTRACT Griscelli Syndrome Type 2 (GS2) is a rare autosomal recessive disorder caused by pathogenic mutations in the RAB27A gene. Typically, it is characterized by cutaneous hypopigmentation, immunodeficiency, with or without neurological abnormalities secondary to hemophagocytic lymphohistiocytosis (HLH). Without treatment, GS2 often results in fatal
Dzhoy Papingi   +6 more
wiley   +1 more source

Altered Nasal Microbiota in Sinonasal Tumors: A Comparative Analysis of Malignant and Benign Sinonasal Tumors

open access: yesInternational Forum of Allergy &Rhinology, Volume 16, Issue 8, Page 778-787, August 2026.
ABSTRACT Background Although shifts in nasal microbiota have been well‐documented in inflammatory upper airway conditions, microbiota tumor‐associated alterations remain uncharacterized. This study is the first to compare sinonasal microbiota profiles of patients with malignant tumors (MT), benign tumors (BT), and controls, offering insights into tumor‐
Evan A. Patel   +13 more
wiley   +1 more source

Genetic‐Proteomic Integration Identifies Predictive Plasma Proteins for Multiple Sclerosis

open access: yesAnnals of Neurology, Volume 100, Issue 2, Page 268-281, August 2026.
Objective Multiple sclerosis (MS) develops after a prolonged preclinical phase. Identifying circulating biomarkers that capture this early biology can improve risk stratification and guide intervention. We aimed to identify plasma proteins driving MS susceptibility using large‐scale proteogenomic integration and to evaluate their prediagnostic ...
Yuan Ding   +5 more
wiley   +1 more source

Early‐Onset Gastric Cancer as a High‐Risk Disease Entity in the United States: Clinicopathologic Features, Regional Variation, and Outcomes

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Introduction Early‐onset gastric cancer (EOGC), defined as diagnosis before age 45, represents a distinct and increasingly recognized subset of gastric cancer. Emerging evidence suggests that clinical behavior, treatment patterns, and outcomes differ from average‐onset disease, yet these differences remain incompletely characterized.
Dani R. Castillo   +12 more
wiley   +1 more source

The Unusual Coexistence of Chronic Lymphocytic Leukemia, Dengue Fever, and Acute Kidney Injury: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT A 70‐year‐old male with CLL presented with dengue fever complicated by AKI. A diagnostic challenge arose from overlapping features. Investigations showed leukocytosis, lymphocytosis, anemia, thrombocytopenia, positive Anti‐Dengue IgM, and renal impairment. Managed with supportive care, ibrutinib, and monitoring, with improvement.
Musawer Khan   +8 more
wiley   +1 more source

Secondary Hemophagocytic Lymphohistiocytosis Complicated by Mucormycosis Following Liver Transplantation for Cryptogenic Acute Liver Failure: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT HLH must be suspected in liver transplant patients who exhibit fever, cytopenia, hyperferritinemia, and dysfunction of the graft. HLH‐2004 guidelines and H‐score assessment early on will aid in early diagnosis and management, although prognosis remains poor when there are opportunistic infections.
Saif Ali Malik   +5 more
wiley   +1 more source

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