Results 81 to 90 of about 303,346 (275)
Education Sciences, 2020 Constructivism proposes that learners construct concepts based on prior knowledge and experiences. Numerous factors may lead to inadequate or improper concept construction, leading to misconceptions.
Jinseok Jung
doaj +1 more source
Stiefel-Whitney Numbers for Singular Varieties
, 2011 This paper determines which Stiefel-Whitney numbers can be defined for singular varieties compatibly with small resolutions. First an upper bound is found by identifying the F_2-vector space of Stiefel-Whitney numbers invariant under classical flops ...
CARL McTAGUE +7 more
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Equating CONTROL with ‘containment’: justifying the equation via animal Farm [PDF]
, 2004 Unless they are expressed in more concrete manners, concepts, which are abstract in nature, are rather difficult to be appreciated. Thus, concepts such as CONTROL, are normally expressed using more concrete means, such as through the hierarchical and the
Khazriyati Salehuddin,
core
Gluino Axion, Neutrino Seesaw, Dynamical Gaugino Mass, and A = 0 Supersymmetry
, 2007 In the axionic solution of the strong CP problem, fermions which transform under quantum chromodynamics (QCD) are required. In supersymmetry, by equating U(1)_{PQ} with U(1)_R, the natural candidates are the gluinos, as pointed out some years ago.
Ma, Ernest
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Two generalizations of Jacobi's derivative formula
, 2005 In this paper we generalize the famous Jacobi's triple product identity, considered as an identity for theta functions with characteristics and their derivatives, to higher genus/dimension.
Grushevsky, Samuel +1 more
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Resisting the Lure of Certainty, Seeking the Unity of Truth: A Nineteenth-Century Voice with Twenty-first-Century Resonance [PDF]
, 2002 In her essay, the author seeks to bring the vision of nineteenth-century American philosopher Charles Sanders Peirce to the attention of those involved in the contemporary debate over the relationship between religion and science. Peirce\'s conception of
Patton, Elizabeth
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source