Results 81 to 90 of about 51,614 (256)
Test equating sleep scales: applying the Leunbach’s model
BMC Medical Research Methodology, 2019 Background In most cases, the total scores from different instruments assessing the same construct are not directly comparable, but must be equated. In this study we aimed to illustrate a novel test equating methodology applied to sleep functions, a ...
Núria Duran Adroher +4 more
doaj +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Penyetaraan (Equating) Ujian Akhir Sekolah Berstandar Nasional (UASBN) Dengan Teori Tes Klasik
Jurnal Pendidikan dan Kebudayaan, 2011 Since the enactment of the National Standard School Final Examination (UASBN) in school year 2007/2008, the province is authorized to construct exam questions based on the same lattice issued BSNP.
Arniati Prasedyawati Herkusumo
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Item Response Theory Observed-Score Kernel Equating
, 2017 Item response theory (IRT) observed-score kernel equating is introduced for the non-equivalent groups with anchor test equating design using either chain equating or post-stratification equating. The equating function is treated in a multivariate setting
Andersson, Björn,, Wiberg, Marie,
core +1 more source
Evaluating equating transformations in IRT observed-score and Kernel Equating methods
, 2023 Test equating is a statistical procedure to ensure that scores from different test forms can be used interchangeably. There are several methodologies available to perform equating, some of which are based on the Classical Test Theory (CTT) framework and ...
Battauz, Michela, +5 more
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Some conceptual issues in observed-score equating [PDF]
, 2013 In spite of all of the technical progress in observed-score equating, several of the more conceptual aspects of the process still are not well understood.
van der Linden, Willem J.
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source