Results 41 to 50 of about 3,132,300 (299)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Geosciences, 2023 Discontinuum Bonded Block Modeling (BBM) represents a potential tool for support design, as these models can reproduce both the rock fracturing process and the influence of reinforcement on unsupported ground. Despite their strengths, discontinuum models
Sankhaneel Sinha, Gabriel Walton
doaj +1 more source
The gauge invariant effective potential: equilibrium and non-equilibrium aspects [PDF]
, 1996 We propose a gauge invariant formulation of the effective potential in terms of a gauge invariant order parameter, for the Abelian Higgs model. The one-loop contribution at zero and finite temperature is computed explicitly, and the leading terms in the ...
A. Guth +50 more
core +5 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Dynamics of many-body quantum synchronisation
New Journal of Physics, 2018 We analyse the properties of the synchronisation transition in a many-body system consisting of quantum van der Pol oscillators with all-to-all coupling using a self-consistent mean-field method.
C Davis-Tilley, C K Teoh, A D Armour
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Particle Yields and Ratios within Equilibrium and Non-Equilibrium Statistics
, 2019 In characterizing the yields and ratios various of well identified particles in the ALICE experiment, we utilize extensive {\it additive} thermal approaches, to which various missing states of the hadron resonances are taken into consideration, as well ...
Elyazeed, Eman R. Abo +2 more
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Essential planetary health workers: Positioning rangers within global policy
Conservation Letters, 2023 Our planet is facing increasing challenges: climate change, biodiversity loss, pandemics, poverty, and many other problems closely linked to a deteriorating environment.
Sue Stolton +14 more
doaj +1 more source
Hyperchaos in a Bose-Hubbard Chain with Rydberg-Dressed Interactions
Photonics, 2021 We study the chaos and hyperchaos of Rydberg-dressed Bose–Einstein condensates (BECs) in a one-dimensional optical lattice. Due to the long-range, soft-core interaction between the dressed atoms, the dynamics of the BECs are described by the extended ...
Gary McCormack, Rejish Nath, Weibin Li
doaj +1 more source