Results 81 to 90 of about 4,274,201 (391)

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Magnetic and electronic properties of porphyrin-based molecular nanowires

AIP Advances, 2016
Using spin-polarized density functional theory calculations, we performed theoretical investigations on the electronic and magnetic properties of transition metal embedded porphyrin-based nanowires (TM-PNWs, TM = Cr, Mn, Co, Ni, Cu, and Zn).
Jia-Jia Zheng, Qiao-Zhi Li, Jing-Shuang Dang, Wei-Wei Wang, Xiang Zhao   +4 more
doaj   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

B-Bridge Regulated Asymmetric Dual-Atomic Catalysts for Synergistically Enhanced Styrene Mineralization and CO2 Reduction

Nano-Micro Letters
Highlights Bifunctional atomic catalyst for dual environmental-energetic applications. Unprecedented catalytic performance: simultaneously 99% flowing-phase styrene degradation and 98% FECO at 1000 mA cm−2.
Xiai Zhang, Zhongshuang Xu, Xinwei Zhang, Jingquan Wang, Dan Liu, Huanran Miao, Tong Wang, Zhimao Yang, Qikui Fan, Chuncai Kong   +9 more
doaj   +1 more source

Bundling Equilibrium in Combinatorial auctions [PDF]

, 2001
This paper analyzes individually-rational ex post equilibrium in the VC (Vickrey-Clarke) combinatorial auctions. If $\Sigma$ is a family of bundles of goods, the organizer may restrict the participants by requiring them to submit their bids only for ...
Dov Monderer, Moshe Tennenholtz, Noa K R-dahav, Noa Kfir-Dahav, Ron Holzman   +4 more
core   +2 more sources

Tsallis statistics generalization of non-equilibrium work relations

, 2012
We use third constraint formulation of Tsallis statistics and derive the $q$-statistics generalization of non-equilibrium work relations such as the Jarzynski equality and the Crooks fluctuation theorem which relate the free energy differences between ...
C. Tsallis, G. Lebon, I. Prigogine, J. Naudts, M. Ponmurugan   +4 more
core   +1 more source

Liquidation Values and Debt Capacity: A Market Equilibrium Approach

, 1992
We explore the determinants of liquidation values of assets, particularly focusing on the potential buyers of assets. When a firm in financial distress needs to sell assets, its industry peers are likely to be experiencing problems themselves, leading to
Andrei Shleifer, Robert W. Vishny
semanticscholar   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Perspective: Stepping Stones to Unraveling the Pathophysiology of Mal de Debarquement Syndrome with Neuroimaging

Frontiers in Neurology, 2018
Mal de debarquement syndrome (MdDS) is a neurological condition typically characterized by a sensation of motion, which in most cases manifests after disembarking from a vehicle (e.g., boat, plane, and car).
Viviana Mucci, Yoon-Hee Cha, Floris L. Wuyts, Angelique Van Ombergen   +3 more
doaj   +1 more source