Results 51 to 60 of about 1,047,095 (303)
Journal of Magnesium and AlloysWE43 magnesium alloy, mainly alloyed with rare earth (RE) elements including Y, Nd and Gd, possesses important application prospects in lightweight structural components and biodegradable biomedical fields.
Hualuo Pang +7 more
doaj +1 more source
Grain refinement efficiency of a new oxide-containing master alloy for aluminium casting alloys [PDF]
, 2014 In this study, grain refinement efficiency of a new oxide master alloy based on MgAl2O4 was demonstrated on an A357 alloy. The grain size of the reference alloy was reduced by 50-60% with the addition of the master alloy and introduction of ultrasonic ...
Dmitry G. Eskin +7 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Abstraction Refinement Guided by a Learnt Probabilistic Model [PDF]
, 2015 The core challenge in designing an effective static program analysis is to find a good program abstraction -- one that retains only details relevant to a given query. In this paper, we present a new approach for automatically finding such an abstraction.
Grigore, R +6 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Resilience: ecological and socio-spatial models evolve while understanding the equilibrium [PDF]
Urbanism. Arhitectura. Constructii, 2016 The paper attempts to review the main models used in systems ecology, and applied to urban and territorial development, in tight connection with the developing understanding of equilibrium and stability. Initially, resilience was perceived as a component
Alexandru-Ionuţ Petrişor +2 more
doaj
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Thermolab: A Thermodynamics Laboratory for Nonlinear Transport Processes in Open Systems
Geochemistry, Geophysics, Geosystems, 2022 We developed a numerical thermodynamics laboratory called “Thermolab” to study the effects of the thermodynamic behavior of nonideal solution models on reactive transport processes in open systems.
J. C. Vrijmoed, Y. Y. Podladchikov
doaj +1 more source
Harmonising the definition of refinement [PDF]
, 2005 Russell and Burch's Three Rs (replacement, reduction and refinement) remain the cornerstone for principles guiding humane experimental research. However, the concept of refinement has evolved considerably since its first inception and there have been ...
Morton, David B +5 more
core
Solid-Liquid Equilibrium Study of Binary System Saturated Fatty Acid in Short Chain Alcohols [PDF]
Unsaturated fatty acids are potential to be used for preventing degenerative diseases and developing brain function in babies. Separation of unsaturated fatty acids from saturated fatty acids efficiently achieved by urea complexation fractionation method.
Plawi, Rudang Suryoadhi Suryatmoko +2 more
core +1 more source