Results 111 to 120 of about 63,057 (294)

Human Pegivirus Encephalitis With Brain Detection and Response to Sofosbuvir Ledipasvir

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Human pegivirus (HPgV‐1) has been associated with severe encephalomyelitis in immunocompromised patients. Its neurological spectrum remains poorly defined. We report a slowly progressive encephalitis in a person living with well‐controlled HIV, characterized by white matter abnormalities and inflammatory cerebrospinal fluid (CSF). HPgV RNA was
Antoine Moulignier   +3 more
wiley   +1 more source

Glucocorticoid Receptor:MegaTrans Switching Mediates Repression of an ERα-Regulated Transcriptional Program

open access: yesMolecules and Cells, 2017
Summary The molecular mechanisms underlying the opposing functions of glucocorticoid receptors (GR) and estrogen receptor α (ERα) in breast cancer development remain poorly understood.
Feng Yang   +11 more
semanticscholar   +1 more source

Distances between MBP and ERα.

open access: yes, 2013
Distances between MBP and ERα.
Charlie Chandsawangbhuwana (31494)   +1 more
core   +1 more source

Long‐Term Neurologic Exam Findings in People Diagnosed and Treated During Acute HIV Infection

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Evaluate clinical and laboratory correlates of abnormal neurologic exam findings after acute HIV infection (AHI). Methods Participants from the RV254/SEARCH 010 cohort in Bangkok underwent standardized neurologic examinations at Weeks 0 (AHI), 12, 96, and 288 following antiretroviral therapy (ART).
Kathryn B. Holroyd   +118 more
wiley   +1 more source

Chronic cadmium exposure decreases the dependency of MCF7 breast cancer cells on ERα

open access: yesScientific Reports, 2019
Cadmium is an environmental contaminant that can activate estrogen receptor alpha (ERα) and contribute to the development and progression of breast cancer. Our lab previously demonstrated that chronic cadmium exposure alters the expression of several ERα-
Mathew Bloomfield, Maggie C. Louie
doaj   +1 more source

ERα down-regulation plays a key role in silibinin-induced autophagy and apoptosis in human breast cancer MCF-7 cells

open access: yesJournal of Pharmacological Sciences, 2015
The estrogen receptor alpha (ERα) has been proven to be one of the most important therapeutic targets in breast cancer over the last 30 years. Previous studies pointed out that a natural flavonoid, silibinin, induced apoptosis in human breast cancer MCF ...
Nan Zheng   +11 more
doaj   +1 more source

The LIM protein Ajuba recruits DBC1 and CBP/p300 to acetylate ERα and enhances ERα target gene expression in breast cancer cells

open access: yesNucleic Acids Research, 2018
Estrogen/ERα signaling is critical for breast cancer progression and therapeutic treatments. Thus, identifying new regulators of this pathway will help to develop new therapeutics to overcome chemotherapy resistance of the breast cancer cells.
Bei-Hui Xu   +10 more
semanticscholar   +1 more source

Modest Effects of Osteoclast‐Specific ERα Deletion after Skeletal Maturity

open access: yes, 2023
Estrogen regulates bone mass in women and men, but the underlying cellular mechanisms of estrogen action on bone remain unclear. Although both estrogen receptor (ER)α and ERβ are expressed in bone cells, ERα is the dominant receptor for skeletal estrogen
Sarah Grain   +10 more
core   +1 more source

Modern Management of Asymptomatic Carotid Stenosis: A Meta‐Analysis of CREST‐2, SPACE‐2, and ECST‐2

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Recent randomized trials (CREST‐2, SPACE‐2, and ECST‐2) have compared carotid revascularization (carotid endarterectomy [CEA] or carotid artery stenting [CAS]) plus contemporary medical therapy (CMT) versus CMT alone in asymptomatic carotid stenosis.
Aasim Ali   +14 more
wiley   +1 more source

Estrogen receptor alpha (ERα) expression in the mouse striatum.

open access: yes, 2016
(A) Photomicrographs show parvalbumin (Parv) (red) and ERα+ (green) staining in male and female coronal sections. Vertical bargraphs on the right indicate the mean percentage ± SEM of the Parv+ cells that are ERα+ (n = 3).
Ivette López-López (3221646)   +3 more
core   +1 more source

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