The eradication of gonorrhoea [PDF]
BMJ, 1994 The continued global survival of Neisseria gonorrhoeae is inevitable because of its immunobiology,1 the seeming lack of natural or acquired immunity, human sexual behaviour, and the frequency of asymptomatic infection. Nevertheless, endemic gonorrhoea could be eradicated from Britain in the 1990s.
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gehalten durch Johannem Burckhardum Erad, Vicarium der Pfarr EffringenGelegenheitsschrift: TodBestattungsdatum: 01.04.1640Lebensdaten: [1632]-29.03.1640Enthält ...
Erad, Johann Burckhard
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Frontiers in NeuroscienceEndoplasmic reticulum-associated degradation (ERAD) is a principal quality-control mechanism responsible for targeting misfolded ER proteins for cytosolic degradation.
Shuangchan Wu +7 more
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Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration
Advanced Science, Volume 13, Issue 53, 24 September 2026.This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya +10 more
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Advanced Science, Volume 13, Issue 53, 24 September 2026.Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu +8 more
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Wohlverdientes Ehren-Gedächtnus/ Bey ... Leichbestattung/ Deß ... Herrn Johan[n] Burckhard Erad/ Fürstl. Margg. Bad. ... Special-Superintendenten der beeden Aempter Pfortzheimb und Stein/ auch ... Pfarrers der Statt Pfortzheimb/ Welcher ... den 28. Novemb. dieses ... 1673. Jahrs in der Statt-Kirchen zu Pfortzheimb ... beygesetzet worden [PDF]
WOHLVERDIENTES EHREN-GEDÄCHTNUS/ BEY ... LEICHBESTATTUNG/ DESS ... HERRN JOHAN[N] BURCKHARD ERAD/ FÜRSTL. MARGG. BAD. ... SPECIAL-SUPERINTENDENTEN DER BEEDEN AEMPTER PFORTZHEIMB UND STEIN/ AUCH ... PFARRERS DER STATT PFORTZHEIMB/ WELCHER ...
Fecht, Johann, Erad, Johann Burckhard
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Functional organisation of the Hrd1 ubiquitin ligase complex and its role in ERAD [PDF]
, 2013 Endoplasmic reticulum (ER)-associated degradation (ERAD) of misfolded proteins of the secretory pathway is crucial for ER homeostasis and the physiological importance of this mechanism is reflected by more than 60 diseases that have been linked to ERAD ...
Schulz, Jasmin
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Mechanism of Sec61-mediated insertion of proteins into the endoplasmic reticulum membrane [PDF]
, 2010 In eukaryotic cells, hydrophobic signal sequences of newly synthesized secretory and membrane proteins target them to the Sec61 translocon in the endoplasmic reticulum (ER) membrane.
Kocik, Lucyna
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WJBF TV tower meteorological database for the ERAD Code-1993
, 1996 The Explosive Release Atmospheric Dispersion (ERAD) model (Boughton and DeLaurentis 1992) is a three-dimensional numerical model for simulating atmospheric transport and dispersion.
Weber, A. H.
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Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland
JCI Insight, 2023 Defects in endoplasmic reticulum (ER) proteostasis have been linked to diseases in multiple organ systems. Here we examined the impact of perturbation of ER proteostasis in mice bearing thyrocyte-specific knockout of either HRD1 (to disable ER-associated
Xiaohan Zhang +11 more
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