Results 11 to 20 of about 2,212 (246)
Frontiers in Cell and Developmental Biology, 2021 The cellular RNA can acquire a variety of chemical modifications during the cell cycle, and compelling pieces of evidence highlight the importance of these modifications in determining the metabolism of RNA and, subsequently, cell physiology.
Mahmoud Bayoumi +2 more
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Biologym6A is an important RNA modification involved in post-transcriptional regulation in plants. However, putative m6A writers and erasers in G. biloba remain poorly characterized.
Yuke Ma +7 more
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The Writers, Readers, and Erasers in Redox Regulation of GAPDH [PDF]
Antioxidants, 2020 Glyceraldehyde 3–phosphate dehydrogenase (GAPDH) is a key glycolytic enzyme, which is crucial for the breakdown of glucose to provide cellular energy. Over the past decade, GAPDH has been reported to be one of the most prominent cellular targets of post ...
Maria-Armineh Tossounian +2 more
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Assay technologies facilitating drug discovery for ADP‐ribosyl writers, readers and erasers [PDF]
, 2022 ADP-ribosylation is a post-translational modification catalyzed by writer enzymes — ADP-ribosyltransferases. The modification is part of many signaling events, can modulate the function and stability of target proteins, and often results in the ...
Lari Lehtiö +5 more
core +1 more source
Tricks and Erasers: Disruption as Performance Pedagogy
, 2020 In Chapter 5 Tricks and Erasers: Disruption as Performance Pedagogy I consider how performative pedagogy, seen through a new lens, reveals that what we might consider to be disruptive and so should challenge established power relations is perhaps ...
Meller, Fred
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Reading and erasing of the phosphonium analogue of trimethyllysine by epigenetic proteins
Communications Chemistry, 2022 N ε-methylation of lysine residues in histones plays an essential role in the regulation of eukaryotic transcription, and understanding the extent to which histone N ε-methyllysine readers and erasers can manifest selectivity is of fundamental and ...
Roman Belle +11 more
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The Potential Roles of RNA N6-Methyladenosine in Urological Tumors
Frontiers in Cell and Developmental Biology, 2020 N6-methyladenosine (m6A) is regarded as the most abundant, prevalent and conserved internal mRNA modification in mammalian cells. M6A can be catalyzed by m6A methyltransferases METTL3, METTL14 and WTAP (writers), reverted by demethylases ALKBH5 and FTO ...
Yang Li +5 more
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Structural and Virus Regulatory Insights Into Avian N6-Methyladenosine (m6A) Machinery
Frontiers in Cell and Developmental Biology, 2020 The addition of a methyl group to the N6 position of adenosine (m6A) is the most common posttranscriptional RNA modification, and it regulates most steps of RNA metabolism including splicing, stability, translation, nuclear-export, and RNA structures ...
Mahmoud Bayoumi +2 more
doaj +1 more source
Emerging Roles of N6-Methyladenosine Modification in Neurodevelopment and Neurodegeneration
Cells, 2021 N6-methyladenosine (m6A), the most abundant modification in messenger RNAs (mRNAs), is deposited by methyltransferases (“writers”) Mettl3 and Mettl14 and erased by demethylases (“erasers”) Fto and Alkbh5.
Liqi Shu +3 more
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The True Effectiveness of Dry-erase Erasers
Journal of Student Research, 2023 Sparked by the interesting observation of the correlation between the omnipresence of dry-erase erasers and their low usage, research to test the actual effectiveness of dry-erase erasers was conducted. Alternatives of relatively similar effectiveness and use were selected to be tested against the dry-erase eraser, with ‘effectiveness’ determined by ...
Nathan Hong, Danilo Tadeo
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