Results 31 to 40 of about 13,813 (161)

Estudo dos mecanismos envolvidos nas respostas contráteis induzidas por agonistas B1 e B2 para as cininas em cólons de camundongos: influência da colite induzida por TNBS [PDF]

, 2007
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em FarmacologiaO presente estudo analisou através de técnicas farmacológicas alguns mecanismos envolvidos na resposta contrátil induzida ...
Hara, Daniela Balz
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Update on HER-2 as a target for cancer therapy: alternative strategies for targeting the epidermal growth factor system in cancer [PDF]

, 2001
The epidermal growth factor (EGF) family of ligands and receptors interact to influence cell division, differentiation and motility. Much evidence supports their importance in causing and sustaining cell transformation in model systems and in human ...
Gullick, William J.
core   +1 more source

Proteomic Profiling of Plasma to Uncover Novel Intervention Targets and Prognostic Biomarkers for Chronic Liver Diseases

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 5029-5042, June 2026.
ABSTRACT Aims The burden of chronic liver disease (CLD) is increasing. This study aims to identify protein markers for CLD and its progression, and develop a protein‐based risk prediction model. Materials and Methods We used proteome‐wide Mendelian randomization (MR), Bayesian colocalization and summary‐data‐based MR with proteomic data from deCODE ...
Xinxuan Li, Jing Sun, Jianhui Zhao, Fangyuan Jiang, Meng Zhang, Hao Wu, Shuai Yuan, Xue Li, Juan Lu, Christos S. Mantzoros   +9 more
wiley   +1 more source

Inferring the lifetime of endosomal protein complexes by fluorescence recovery after photobleaching [PDF]

, 2008
Cellular signal transduction is dynamic, with signaling proteins continually associating and dissociating into and from protein complexes. Here we present a fluorescence recovery after photobleaching technique to determine the lifetime of protein ...
Gousseva, Veronika, Laporte, Stéphane A., Swain, Peter S, Swain, Peter S., Simaan, May, Laporte, Stéphane A   +5 more
core   +1 more source

The predictive and prognostic significance of c-erb-B2, EGFR, PTEN, mTOR, PI3K, p27, and ERCC1 expression in hepatocellular carcinoma

, 2012
İstanbul Bilim Üniversitesi, Tıp Fakültesi.BACKGROUND: Hepatocellular carcinoma (HCC) is the fifth most common fatal cancer and an important healthcare problem worldwide.
Yağız Korkmaz, Pınar, Yaşar, Reyhan, Akyıldız, Murat, Türkmen, İlknur, Dayangaç, Murat, Başsüllü, Nuray, Bülbül Doğusoy, Gülen   +6 more
core   +2 more sources

Papel do receptor B2 para as cininas na neuroinflamação induzida pelo peptídeo beta-amilóide [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia.O objetivo do presente estudo foi investigar o papel do receptor B2 para as cininas na neuroinflamação induzida pelo
Bicca, Maíra Assunção
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Human iPSC‐derived GABAergic interneuron transplantation restores circuit balance and cognitive function in an Alzheimer's disease model

Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) is characterized by disrupted excitatory–inhibitory (E:I) balance and impaired synaptic function, yet current treatments fail to repair these fundamental circuit impairments. METHODS Human induced pluripotent stem cell‐derived post‐mitotic medial ganglionic eminence‐originated inhibitory neurons (MGE‐pINs)
Xinzhe Zhang, Gaojie Wang, Haodong Chen, Ye Sun, Ziteng Wangliu, Lijing Wang, Miao Sun, Qing Liu, Xue Zhang   +8 more
wiley   +1 more source

A Narrative Review of Antioxidant, Anti‐Inflammatory, Anti‐Apoptotic, Immunomodulatory, and Anticancer Properties of Rosa damascena Mill.

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Rosa damascena Mill. exhibits a broad spectrum of pharmacological activities mediated by its rich phytochemical profile. The plant enhances antioxidant defenses by increasing endogenous enzymes (CAT, SOD, GSH, GST, GPx, FRAP) and reducing oxidative stress markers (MDA, MPO).
Mahboobeh Ghasemzadeh Rahbardar, Nikta Soltani, Mohammad Hossein Boskabady   +2 more
wiley   +1 more source

Estudos farmacológicos e bioquímicos dos mecanismos envolvidos na regulação da expressão do receptor B1 para as cininas [PDF]

, 2001
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia.O presente estudo avaliou, através de técnicas moleculares e farmacológicas, o efeito dos glicocorticóides endógenos sobre
Cabrini, Daniela de Almeida
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Studies of suppression using monoclonal regulatory T cells and the importance of co-receptor Lck coupling ratios for negative selection [PDF]

, 2015
Normal physiology is not given without immunological tolerance. Depending on the origin of induction, tolerance can be divided into central and peripheral tolerance.
Gubser, Céline
core   +1 more source