Results 61 to 70 of about 95,906 (268)

Helicobacter pylori infection and expressions of EGF, EGFR and c-erbB-2 proteins in gastric carcinoma.

Folia Histochemica et Cytobiologica, 2010
The family of epidermal growth factor (EGF, EGFR, c-erbB-2) plays a pivotal role in gastric cancer progression, invasion and metastasizing. Helicobacter pylori infection is known to contribute significantly to the formation and progression of gastric ...
Andrzej Kemona, Katarzyna Guzińska-Ustymowicz, Anna Pryczynicz, Jolanta Czyzewska   +3 more
doaj   +1 more source

Disease-specific, neurosphere-derived cells as models for brain disorders [PDF]

, 2010
There is a pressing need for patient-derived cell models of brain diseases that are relevant and robust enough to produce the large quantities of cells required for molecular and functional analyses.
Abrahamsen, G., An, J., Anderson, M., Beckhouse, A.G., Bellette, B., Bennebroek, M., Cecil, R., Chalk, A.M., Cochrane, J., Cook, A.L., Fan, Y., Féron, F., Mackay-Sim, A., Mahler, S., Matigian, N., McCurdy, R., McGrath, J.J., Mellick, G.D., Murrell, W., Nouwens, A., Perry, C., Raju, J., Ravishankar, S., Silburn, P.A., Sue, C.M., Sutharsan, R., Sutherland, G.T., Vitale, A.M., Wells, C.A., Wood, S.A.   +29 more
core   +1 more source

Selective Formation of ErbB-2/ErbB-3 Heterodimers Depends on the ErbB-3 Affinity of Epidermal Growth Factor-like Ligands [PDF]

Journal of Biological Chemistry, 2003
EGF-like growth factors activate their ErbB receptors by promoting receptor-mediated homodimerization or, alternatively, by the formation of heterodimers with the orphan ErbB-2 through an as yet unknown mechanism. To investigate the selectivity in dimer formation by ligands, we have applied the phage display approach to obtain ligands with modified C ...
Stortelers, C., Woning, S.P. van der, Jacobs-Oomen, S., Wingens, M., Zoelen, E.J.J. van   +4 more
openaire   +3 more sources

RADA16 and SAAP148 Peptide‐Modified Collagen Self‐Assembled Hydrogels for Accelerated Healing of Infected Wounds

Advanced Science, EarlyView.
Collagen type I (Col I) is integrated with self‐assembling peptide RADA16 and loaded with anti‐bacterial peptide SAAP148 to develop a self‐assembled nano‐microstructure hydrogel (Col I‐RADA16‐SAAP148, CRS) without chemical cross‐linkers. CRS exhibits excellent mechanical properties, sustained SAAP148 release to inhibit bacterial infection, macrophage ...
Qian Liu, Jiawei Wu, Ho‐Pan Bei, Yufei Chen, Yifan Zhang, Xueliang Peng, Fulin Chen, Xin Zhao, Zhuoyue Chen   +8 more
wiley   +1 more source

Enhanced antiproliferative and apoptotic response to combined treatment of γ-tocotrienol with erlotinib or gefitinib in mammary tumor cells

BMC Cancer, 2010
Background Aberrant ErbB receptor signaling is associated with various types of malignancies. γ-Tocotrienol is a member of the vitamin E family of compounds that displays potent anticancer activity that is associated with suppression in ErbB receptor ...
Sylvester Paul W, Wali Vikram B, Bachawal Sunitha V   +2 more
doaj   +1 more source

Detection of chromosome aberrations in metaphase and interphase tumor cells by in situ hybridization using chromosome-specific library probes [PDF]

, 1988
Chromosome aberrations in two glioma cell lines were analyzed using biotinylated DNA library probes that specifically decorate chromosomes 1, 4, 7, 18 and 22 from pter to qter.
A Al-Saadi, AG Knudson, B Trask, CD Bloomfield, D Pinkel, D. C. Ward, F Mitelman, G Rappold, GM Brodeur, GT Merlino, H Harris, H Yamazaki, HE McDermid, J Burns, J. Borden, JA Rey, JE Landegent, JR Shapiro, JS Waye, L Larizza, L Manuelidis, L Manuelidis, L Manuelidis, L. Manuelidis, LC Showe, M Schardin, MF Hansen, NB Atkin, P Lichter, P. Lichter, SH Bigner, SH Bigner, SH Bigner, T Boveri, T Cremer, T Cremer, T. Cremer, TA Libermann, W Henn   +38 more
core   +1 more source

ErbB Receptors and ErbB Targeted Therapies in Endometrial Cancer

Journal of Cancer Therapy, 2014
The Epidermal Growth Factor system is present in human organs and plays an important role in cell proliferation, differentiation and apoptosis during embryogenesis and postnatal development. It has four receptors (EGFR, ErbB-2, ErbB-3 and ErbB-4) and numerous ligands.
Georgios Androutsopoulos, Georgios Michail, Georgios Adonakis, Georgios Decavalas   +3 more
openaire   +2 more sources

Identification of ferroptosis‐related genes involved in chronic obstructive pulmonary disease based on bioinformatics analysis

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Green part represents the bioinformatics analysis approach. Yellow part represents the ideas of animal experiment. Abstract Background Chronic obstructive pulmonary disease (COPD) is a type of chronic respiratory disease.
Xuejing Luan, Jinghui Xie, Lu Zhang, Xiao Ma, Lichangtian Jiao, Jie Zhu   +5 more
wiley   +1 more source

Preliminary study of p53 and c-erbB-2 expression in gallbladder cancer in Indian patients

BMC Cancer, 2006
Background The inactivation of the tumour suppressor gene and activation of the proto-oncogene are the key steps in the development of the human cancer. The p53 and c-erbB-2 are the best examples of it.
Singh Usha, Garbyal RS, Tewari Mallika, Chaube Amita, Shukla Hari S   +4 more
doaj   +1 more source

ER and HER2 expression are positively correlated in HER2 non-overexpressing breast cancer [PDF]

, 2012
PMCID: PMC3446380This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided ...
A Borg, AC Wolff, Adrian Harris, C Wright, DA Budwit-Novotny, DJ Slamon, DJ Slamon, E Tagliabue, EA Musgrove, EHR Perez, G Arpino, G Konecny, GD Lewis Phillips, Georges Sumo, IL Andrulis, Isabel Pinhel, Ivana Sestak, J Cuzick, J Vandesompele, JA Sparano, Jack Cuzick, Janine Salter, JC Brase, JM Harvey, Judith M Bliss, M Dowsett, M Dowsett, M Harigopal, Margaret Hills, ME Hammond, MF Press, Mitch Dowsett, MJ Ellis, MJ Ellis, MJ Piccart-Gebhart, N Quenel, P Royston, Peter Barrett-Lee, RL Camp, Roger A'Hern, S Drury, S Johnston, S Paik, SJ Houston, SS Badve, Suzanne Drury, The Adjuvant Breast Cancer Trials Collaborative Group, V Guarneri, VS Perez   +48 more
core   +5 more sources