Results 131 to 140 of about 2,350,327 (205)

Structure-Based Network Analysis of Activation Mechanisms in the ErbB Family of Receptor Tyrosine Kinases: The Regulatory Spine Residues Are Global Mediators of Structural Stability and Allosteric Interactions

, 2014
Kevin A. James, Gennady M. Verkhivker
openalex   +2 more sources

The Metastasis Suppressor, N-MYC Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling Pathways [PDF]

, 2015
Žaklina Kovačević, Sharleen V. Menezes, Sumit Sahni, Danuta S. Kalinowski, Dong-Hun Bae, Darius J.R. Lane, Des R. Richardson   +6 more
openalex   +1 more source

p53 protein expression in human breast carcinoma: relationship to expression of epidermal growth factor receptor, c-erbB-2 protein overexpression, and oestrogen receptor [PDF]

, 1992
DN Poller, C. E. Hutchings, M Galea, JA Bell, R. Nicholson, CW Elston, RW Blamey, Ian O. Ellis   +7 more
openalex   +1 more source

The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors.

Molecules and Cells, 2003
T. Garrett, N. Mckern, M. Lou, T. Elleman, T. Adams, G. Lovrecz, M. Kofler, R. Jorissen, E. Nice, A. Burgess, C. Ward   +10 more
semanticscholar   +1 more source

Surface plasmon resonance microscopy reveals N-glycosylation driven modulation of affinity and avidity of ErbB receptors in whole single pancreatic cancer cells. [PDF]

Glycobiology
Aguilar Díaz de León JS, Thirumurthy M, Ly N.   +2 more
europepmc   +1 more source

In vitro synergistic effect of AXL, FAK and ErbB receptors inhibitors for head and neck cancer. [PDF]

Biol Direct
Lucarini V, Angiolini V, Nardozi D, Benvenuto M, Focaccetti C, Mancini P, Splendiani E, Autilio TM, Cortese C, Bei R, Nicolai G, Palumbo C, Ferretti E, Cifaldi L, Bei R, Masuelli L.   +15 more
europepmc   +1 more source

Variation of hormonal receptor, pS2, c-erbB-2 and GSTπ contents in breast carcinomas under tamoxifen: a study of 74 cases [PDF]

, 1996
Isabelle Soubeyran, Nathalie Quénel, L. Mauriac, M. Durand, F. Bonichon, Coindre Jm   +5 more
openalex   +1 more source

Data from AZD8931, an Equipotent, Reversible Inhibitor of Signaling by Epidermal Growth Factor Receptor, ERBB2 (HER2), and ERBB3: A Unique Agent for Simultaneous ERBB Receptor Blockade in Cancer

, 2023
D. Mark Hickinson, Teresa Klinowska, Georgina Speake, John Vincent, Cath Trigwell, Judith Anderton, Sarah R. Beck, Gayle Marshall, Sara Davenport, Rowena Callis, E. N. Clare Mills, Konstantina Grosios, Paul Smith, Bernard Barlaam, Robert W. Wilkinson, Donald Ogilvie   +15 more
openalex   +1 more source

MEK inhibition leads to PI3K/AKT activation by relieving a negative feedback on ERBB receptors.

Cancer Research, 2012
Alexa B. Turke, Youngchul Song, C. Costa, R. Cook, C. Arteaga, J. Asara, J. Engelman   +6 more
semanticscholar   +1 more source

Natural Products as Chemopreventive Agents by Potential Inhibition of the Kinase Domain in ErbB Receptors. [PDF]

Molecules, 2017
Olivero-Acosta M, Maldonado-Rojas W, Olivero-Verbel J.   +2 more
europepmc   +1 more source