Results 131 to 140 of about 60,784 (262)

ERBB Receptors and Their Ligands in the Developing Mammary Glands of Different Species: Fifteen Characters in Search of an Author. [PDF]

J Mammary Gland Biol Neoplasia, 2023
Morato A, Accornero P, Hovey RC.
europepmc   +1 more source

Epigen, the Last Ligand of ErbB Receptors, Reveals Intricate Relationships between Affinity and Mitogenicity [PDF]

, 2004
Bose Kochupurakkal, Daniel Harari, Ayelet Di‐Segni, Galia Maik-Rachline, Ljuba Lyass, Gal Gur, Gabriele Kerber, Ami Citri, Sara Lavi, Raya Eilam, Vered Chalifa‐Caspi, Zelig Eshhar, Eli Pikarsky, Ronit Pinkas‐Kramarski, Sarah Bacus, Yosef Yarden   +15 more
openalex   +1 more source

The Influence of Schwann Cell Metabolism and Dysfunction on Axon Maintenance

Glia, Volume 73, Issue 12, Page 2338-2352, December 2025.
Main Points Sensory neurons depend on Schwann cells for survival. Schwann cells provide energy for axons dunng rapid firing or after injury. Dysregulated metabolism in Schwann cells can lead to the production of neurotoxic and axon degeneration. ABSTRACT Schwann cells are the glial cells in the peripheral nervous system responsible for the production ...
Rose Follis, Vishwanath V. Prabhu, Bruce D. Carter   +2 more
wiley   +1 more source

Input–output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data

Molecular Systems Biology, 2009
The ErbB signaling pathways, which regulate diverse physiological responses such as cell survival, proliferation and motility, have been subjected to extensive molecular analysis.
William W Chen, Birgit Schoeberl, Paul J Jasper, Mario Niepel, Ulrik B Nielsen, Douglas A Lauffenburger, Peter K Sorger   +6 more
doaj   +1 more source

Structural arrangement of the active back-to-back dimer in N-glycosylated ErbB receptors is regulated by heterodimerization. [PDF]

Mol Biol Res Commun, 2023
Mashayekh-Poul R, Azimzadeh-Irani M, Masoomi-Nomandan SZ.   +2 more
europepmc   +1 more source

ON-III inhibits erbB-2 tyrosine kinase receptor signal pathway and triggers apoptosis through induction of Bim in breast cancer cells [PDF]

, 2009
Dan-Dan Li, Xiao-Qi Wu, Jun Tang, Xiao-Yi Wei, Xiao‐Feng Zhu   +4 more
openalex   +1 more source

Myostatin Exhibits an Evolutionarily Conserved Circadian Pattern in Skeletal Muscles

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Introduction Myostatin (MSTN), a transforming growth factor‐beta (TGF‐β) superfamily member, is an evolutionarily conserved negative regulator of skeletal muscle mass. Loss of MSTN commonly promotes augmentation in skeletal muscle mass in all animal species examined.
Xiangpeng Liu, Changyou Song, Yan Xiong, Jinxin Gu, Lianxin Wu, Taole Liu, Xiyue Chen, Hui Shu, Yingying Dong, Tizhong Shan, Sheng Wang, Yucheng Zhu, Tongxing Song, Lei Fu, Yaqiu Lin, Can Liu, Ruiqi Zheng, Xiao Zhao, Hongxia Li, Yong Xu, Shihuan Kuang, Han Wang, Bin Guo, Pao Xu, Zhihao Jia   +24 more
wiley   +1 more source

Ligand‐dependent responses of the ErbB signaling network: experimental and modeling analyses

Molecular Systems Biology, 2007
Deregulation of ErbB signaling plays a key role in the progression of multiple human cancers. To help understand ErbB signaling quantitatively, in this work we combine traditional experiments with computational modeling, building a model that describes ...
Marc R Birtwistle, Mariko Hatakeyama, Noriko Yumoto, Babatunde A Ogunnaike, Jan B Hoek, Boris N Kholodenko   +5 more
doaj   +1 more source

Enhanced antiproliferative and apoptotic response to combined treatment of γ-tocotrienol with erlotinib or gefitinib in mammary tumor cells

BMC Cancer, 2010
Background Aberrant ErbB receptor signaling is associated with various types of malignancies. γ-Tocotrienol is a member of the vitamin E family of compounds that displays potent anticancer activity that is associated with suppression in ErbB receptor ...
Sylvester Paul W, Wali Vikram B, Bachawal Sunitha V   +2 more
doaj   +1 more source

ERBB Receptor Regulation of ESX/ELF3 Promotes Invasion in Breast Epithelial Cells [PDF]

, 2010
Jean Philippe Coppé, Clifton Amend, Jeremy R. Semeiks, Frederick L. Baehner, Nora Bayani, Judith Campisi, Christopher C. Benz, Joe W. Gray, Richard M. Neve   +8 more
openalex   +1 more source