Results 121 to 130 of about 1,990 (193)

Biosynthesis of Ergot Alkaloids. Evidence for Two Isomerizations in the Isoprenoid Moiety During the Formation of Tetracyclic Ergolines

Journal of the American Chemical Society, 1968
U Hornemann, H G Floss, Heinz G Floss
exaly   +2 more sources

Antiprolactinic Ergolines

Experientia, 1980
L Bernardi
exaly   +2 more sources

Effect of 5-HT2 Receptor Antagonist Ergolines and Their Desisopropyl Metabolites on Rabbit Platelet Aggregation in Vitro and Ex Vivo

Drug Development Research, 1994
Marlene L Cohen
exaly   +2 more sources

Synthesis of D-Oxa Tricyclic Partial Ergolines as Dopamine Agonists

Journal of Medicinal Chemistry, 1987
J A Clemens, Edmund C Kornfeld
exaly   +2 more sources

Ergoline and non-ergoline derivatives in the treatment of Parkinson’s disease

Journal of Neurology, 2006
There are a large variety of dopamine agonists available. Especially de novo patients are treated with dopamine agonists to avoid dyskinesia. Dopamine agonists can be subdivided into ergoline and non-ergoline derivatives. This distinction raises the question whether there are differences in the effects to treat symptoms, not only in the side effects ...
Heinz, Reichmann, Anja, Bilsing, Reinhard, Ehret, Wolfgang, Greulich, Jörg B, Schulz, Andreas, Schwartz, Olivier, Rascol   +6 more
openaire   +2 more sources

Preparation and Characterization of Ergoline Thiazolidinones and an Ergoline Imidazolidinone

Archiv der Pharmazie, 1986
AbstractThe preparation of the ergoline thiazolidinones 2,3 and the ergoline imidazolidinone 5 is described. The 13C‐ and 15N‐NMR spectra of the 15N‐labelled compounds 15N‐ 2a and 15N‐3a allow the distinction of the two isomers.
Karlheinz Seifert, Sigrid Härtling, Siegfried Johne   +2 more
openaire   +1 more source

Stimulation of pre- and postsynaptic dopamine receptors by an ergoline and by a partial ergoline

Brain Research, 1981
The capacity of the ergoline, pergolide, and of the partial ergoline, LY 141865, to stimulate pre- and postsynaptic dopamine (DA) receptors was investigated. Binding studies have revealed that pergolide has a high affinity, while the partial ergoline, LY 141865, has a low affinity for the postsynaptic striatal DA receptors in vitro.
J M, Rabey, P, Passeltiner, K, Markey, T, Asano, M, Goldstein   +4 more
openaire   +2 more sources

Serotonergic ergoline derivatives

Bioorganic & Medicinal Chemistry Letters, 1998
Novel classes of 13- and 14-tertbutyl-ergoline derivatives were prepared, and characterised in vitro for their affinity for adrenergic, dopaminergic and serotonergic binding sites. This study particularly examines the importance of the presence and the position of the tert-butyl group in conferring either significant 5-HT1A or 5-HT2 affinity and ...
S, Mantegani, E, Brambilla, C, Caccia, G, Damiani, M G, Fornaretto, R A, McArthur, M, Varasi   +6 more
openaire   +2 more sources

Differential ergoline and ergopeptine binding to 5-hydroxytryptamine2A receptors: ergolines require an aromatic residue at position 340 for high affinity binding.

Molecular Pharmacology, 1995
In this paper we show that a highly conserved aromatic residue, phenylalanine at the 340-position, is essential for ergoline binding to 5-hydroxytryptamine2A receptors. We hypothesized that F340 was essential for a specific aromatic-aromatic interaction (
M. S. Choudhary, N. Sachs, Ahmet Uluer, R. Glennon, R. Westkaemper, B. L. Roth   +5 more
semanticscholar   +1 more source

ChemInform Abstract: Preparation and Characterization of Ergoline Thiazolidinones and an Ergoline Imidazolidinone.

Chemischer Informationsdienst, 1986
AbstractErgolin‐thioharnstoffe (I) reagieren mit Acetylendicarbonsäureestern (II) zum Isomerengemisch der Ergolin‐thiazolidinone (III) und (IV).
K. SEIFERT, S. + HAERTLING, S. JOHNE
openaire   +1 more source