Results 11 to 20 of about 2,476 (230)

Genetics of ergoline alkaloid formation in Penicillium roquefortii [PDF]

Applied and Environmental Microbiology, 1985
Auxotrophic, spore color, and alkaloid biosynthetic mutants of Penicillium roquefortii were selected after N-methyl-N'-nitro-N-nitrosoguanidine treatment. Diploids were obtained via protoplast fusion techniques, and the segregants from a diploid were genetically analyzed. The data demonstrated the potential of parasexual recombination in this organism.
Shuai Hong, James E. Robbers
openalex   +3 more sources

Evidence that 5‐HT 2A receptor signalling efficacy and not biased agonism differentiates serotonergic psychedelic from non‐psychedelic drugs [PDF]

British Journal of Pharmacology, EarlyView.
Background and Purpose: Serotonergic psychedelic drugs are under investigation as therapies for various psychiatric disorders, including major depression.
Churchill, Grant, Gilmour, Gary, Hurley, Shaun, Ippolito, Aurelija, Sharp, Trevor, Vasudevan, Sridhar, Westhorpe, Frederick   +6 more
core   +3 more sources

Synthesis of 5(10Æ9)abeo-Ergolines

HETEROCYCLES, 1997
Sergio Mantegani, E. Arlandini, Daniela Borghi, Enzo Brambilla, Mario Varasi   +4 more
semanticscholar   +3 more sources

Serotonergic ergoline derivatives

Bioorganic & Medicinal Chemistry Letters, 1998
Novel classes of 13- and 14-tertbutyl-ergoline derivatives were prepared, and characterised in vitro for their affinity for adrenergic, dopaminergic and serotonergic binding sites. This study particularly examines the importance of the presence and the position of the tert-butyl group in conferring either significant 5-HT1A or 5-HT2 affinity and ...
Sergio Mantegani, Enzo Brambilla, Carla Caccia, Gabriele Damiani, Maria Gioia Fornaretto, Robert A. McArthur, Mario Varasi   +6 more
openalex   +3 more sources

Synthesis of ergoline ethers

, 2012
The photoaddition of water to the ergot clavinet alkaloid, lysergene, has been reported by Shough and Taylor. The product of this reaction, 10-hydroxyagroclabine, was found to rearrange in aqueous acid to give the 8-hydroxy derivative setoclavine. A second photoaddition of water than gave the 8,10-dihydroxy derivative, lumisetoclavine.
Brian Thompson
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Novel Ergoline Compounds as 5-HT2A Agonists for Treating Mood Disorders Such as Depressive Disorders and Bipolar Disorders. [PDF]

ACS Med Chem Lett
Sabnis RW.
europepmc   +3 more sources

Species differences in the pharmacology of the 5-hydroxytryptamine2 receptor: structurally specific differentiation by ergolines and tryptamines.

Journal of Pharmacology and Experimental Therapeutics, 1993
David L. Nelson, Virginia L. Lucaites, James E. Audia, Jeffrey S. Nissen, David B. Wainscott   +4 more
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Galactorrhea: how to address this unusual complication after augmentation mammoplasty [PDF]

Revista Brasileira de Cirurgia Plástica, 2016
INTRODUCTION: Galactorrhea and galactocele formation after breast augmentation are complications reported in the literature, but the cause remains unknown.
Adriana Sayuri Kurogi Ascenço, Ruth Graf, Ivan Maluf Junior, Priscila Balbinot, Renato da Silva Freitas   +4 more
doaj   +1 more source

Special ergolines are highly selective, potent antagonists of the chemokine receptor CXCR3: Discovery, characterization and preliminary SAR of a promising lead

Bioorganic & Medicinal Chemistry Letters, 2009
Gebhard Thoma, Rolf Baenteli, Ian Lewis, Trixie Wagner, Lukas Oberer, W. Blum, Fraser Glickman, Markus Streiff, Hans‐Günter Zerwes   +8 more
openalex   +2 more sources

Special ergolines efficiently inhibit the chemokine receptor CXCR3 in blood

Bioorganic & Medicinal Chemistry Letters, 2011
Gebhard Thoma, Rolf Baenteli, Ian Lewis, Darryl Jones, Jiří Kovařík, Markus Streiff, Hans‐Günter Zerwes   +6 more
openalex   +2 more sources