Ropinirole, a Non‐Ergoline Dopamine Agonist [PDF]
ABSTRACTDopamine agonists have become indispensable in the treatment of Parkinson's disease. In every‐day practice, however, the decision to select the best compound for an individual patient is rendered difficult because of the large number of substances available on the market.
Dieter Angersbach, Wolfgang H. Jost
openaire +4 more sources
Pleuropulmonary changes induced by ergoline drugs [PDF]
Classic ergolines, such as bromocriptine, methysergide and ergotamine, can induce chronic pleuropneumonitis. We present the cases of eight patients who developed similar changes whilst on other ergolines. In this retrospective case study spanning 1985-1995, clinical data, radiological material, pulmonary function, bronchoalveolar lavage and ...
Ph. Camus +7 more
openaire +4 more sources
Genetics of ergoline alkaloid formation in Penicillium roquefortii [PDF]
Auxotrophic, spore color, and alkaloid biosynthetic mutants of Penicillium roquefortii were selected after N-methyl-N'-nitro-N-nitrosoguanidine treatment. Diploids were obtained via protoplast fusion techniques, and the segregants from a diploid were genetically analyzed. The data demonstrated the potential of parasexual recombination in this organism.
S L Hong, J E Robbers
openaire +4 more sources
Introduction: Serotonergic psychedelics induce their characteristic subjective effects via activation of the serotonin 2A receptor (5-HT2AR). This structurally diverse class of drugs includes ergolines (e.g., LSD), phenethylamines (e.g., mescaline), and ...
E. Pottie +3 more
doaj +2 more sources
Evidence that 5‐HT 2A receptor signalling efficacy and not biased agonism differentiates serotonergic psychedelic from non‐psychedelic drugs [PDF]
Background and Purpose: Serotonergic psychedelic drugs are under investigation as therapies for various psychiatric disorders, including major depression.
Churchill, Grant +6 more
core +3 more sources
Psilocybin as Transformative Fast-Acting Antidepressant: Pharmacological Properties and Molecular Mechanisms. [PDF]
ABSTRACT In the 1950s–60s, serotonergic psychedelic drugs were studied as potential adjuvants to psychotherapy to treat addiction and alcoholism. However, starting in the 70s, preclinical and clinical studies on psychedelics stopped for decades because legislation controlled its recreational use, citing their hallucinogenic and psychotomimetic effects,
Adebo M +9 more
europepmc +2 more sources
In-situ steel solidification imaging in continuous casting using magnetic induction tomography [PDF]
: Solidification process in continuous casting is a critical part of steel production. The speed and quality of the solidification process determines the quality of final product.
Barbero, J +6 more
core +3 more sources
The varieties of the psychedelic experience: A preliminary study of the association between the reported subjective effects and the binding affinity profiles of substituted phenethylamines and tryptamines [PDF]
Classic psychedelics are substances of paramount cultural and neuroscientific importance. A distinctive feature of psychedelic drugs is the wide range of potential subjective effects they can elicit, known to be deeply influenced by the internal state of
Erowid, Earth +6 more
core +2 more sources
Novel Psychoactive Substances: : the pharmacology of stimulants and hallucinogens [PDF]
This is an Accepted Manuscript of an article published by Taylor & Francis in Expert Review of Clinical Pharmacology, on March 2016, available online at doi: : http://www.tandfonline.com/doi/full/10.1586/17512433.2016.1167597.There are increasing levels ...
Corkery JM +11 more
core +3 more sources
Recreational use, analysis and toxicity of tryptamines [PDF]
The definition New psychoactive substances (NPS) refers to emerging drugs whose chemical structures are similar to other psychoactive compounds but not identical, representing a "legal" alternative to internationally controlled drugs.
Mannocchi, Giulio +3 more
core +1 more source

