Results 41 to 50 of about 2,476 (230)

Vertebral arteries do not experience tensile force during manual cervical spine manipulation applied to human cadavers [PDF]

, 2022
Background: The vertebral artery (VA) may be stretched and subsequently damaged during manual cervical spine manipulation. The objective of this study was to measure VA length changes that occur during cervical spine manipulation and to compare these to ...
Edwards, W Brent, Gorrell, Lindsay Mary, Herzog, Walter, Sawatsky, Andrew   +3 more
core   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Assessing the exercise‐related kinetics of circulating cell‐free DNA, circulating tumour DNA, DNase I activity and cytokines in patients with solid tumours: A pilot study

Experimental Physiology, EarlyView.
Abstract Circulating cell‐free DNA (cfDNA), circulating tumour DNA (ctDNA) and inflammatory cytokines have prognostic and predictive value in oncology. However, the effects of acute exercise on cfDNA levels are unknown. Here, we explore the kinetics of cfDNA, ctDNA and cytokines upon an incremental exercise test in a pilot cohort of cancer patients ...
Elmo W. I. Neuberger, Alexandra Brahmer, Tobias Ehlert, Suzan Botzenhardt, Alfonso De Falco, Birgit Enders, Patricia S. Hähnel, Achim Heintz, Carl C. Schimanski, Thomas Kindler, Perikles Simon   +10 more
wiley   +1 more source

N-Benzyl-5-methoxytryptamines as Potent Serotonin 5-HT2 Receptor Family Agonists and Comparison with a Series of Phenethylarnine Analogues [PDF]

A series of N-benzylated-5-methoxytryptamine analogues was prepared and investigated, with special emphasis on substituents in the meta position of the benzyl group.
Brandt, SD, Elliott, SP, Fiedler, WJ, Halberstadt, AL, Klein, LM, Nichols, DE, Sassano, MF   +6 more
core   +1 more source

Effect of moderate altitude and nocturnal oxygen therapy on cerebrovascular function in patients with COPD: A randomized, crossover trial at 2048 m

Experimental Physiology, EarlyView.
Abstract We investigated whether nocturnal oxygen therapy improves next‐day cerebrovascular function in lowlanders with chronic obstructive pulmonary disease (COPD) staying at moderate altitude. This randomized, placebo‐controlled single‐blind crossover trial was performed in moderate‐to‐severe COPD patients [forced expiratory volume in 1 s (FEV1 ...
Dominic Gilliand, Tsogyal D. Latshang, Sayaka S. Aeschbacher, Fabienne Huber, Deborah Flueck, Mona Lichtblau, Stefanie Ulrich, Elisabeth D. Hasler, Philipp M. Scheiwiller, Julian Müller, Silvia Ulrich, Konrad E. Bloch, Michael Furian   +12 more
wiley   +1 more source

Conformational Analysis of the D Ring of Lysergic Acid Amides and its Bioactive Conformation [PDF]

, 1985
1H, 13Cnuclear magnetic resonance data on simple lysergic acid amides and ergopeptines indieate eonsiderable flexibility of the D ring. The actual conformation depends upon the existence (or absence) of intramolecular hydrogen bonding between N6 and the ...
Darko Kocjan, Dušan Hadži, Jurkica Kidrič   +2 more
core   +3 more sources

The History and Pharmacology of Dopamine Agonists [PDF]

, 2017
The recognition of the dopaminergic properties of some ergot derivatives has initiated new therapeutical approaches in endocrinology as well as in neurology.
Lataste, X.
core  

Peak V̇O2Q${\dot V_{{{\mathrm{O}}_2}{\mathrm{Q}}}}$: A new approach for the interpretation of cardiorespiratory fitness estimates

Experimental Physiology, EarlyView.
Abstract There are difficulties with the standardisation of interpretative strategies for peak oxygen uptake (peak V̇O2${\dot V_{{{\mathrm{O}}_2}}}$) related to the quality of reference equations. We aimed to investigate the utility of peak V̇O2Q${\dot V_{{{\mathrm{O}}_2}{\mathrm{Q}}}}$, a novel method reflecting how far a measured value is from the ...
Ben Knox‐Brown, Joshua Barnes, Chris Harding, Jonathan Fuld, Karl P. Sylvester   +4 more
wiley   +1 more source

Sex differences in the prefrontal cortex and muscle oxygenation during exercise until exhaustion in endurance‐trained individuals

Experimental Physiology, EarlyView.
Abstract figure legend During cardiopulmonary exercise testing, the decline in oxygenation in the prefrontal cortex of women is striking. This crucial brain area is directly involved in planning motor tasks. The decline is particularly pronounced at higher exercise intensities, especially after reaching the respiratory compensation point or anaerobic ...
Daniel Ramos‐López, Raúl Caulier‐Cisterna, Benjamín Díaz‐Ortiz, Cristóbal Baumann‐Biancani, Kamilo Hunger‐Abbott, Matías Herrera‐Matas, Andrés Vega‐Moraga, Vitor A. Lira, Maximiliano Espinosa‐Ramírez, Karol Ramírez‐Parada, Luigi Gabrielli‐Nervi, Hugo E. Verdejo, Felipe Contreras‐Briceño   +12 more
wiley   +1 more source

PhD [PDF]

, 2008
dissertationEarlier studies have demonstrated the peroxidase oxidation of the delta8-ergolines agroclavine and elymoclavine to their respective 10-hydroxy-delta9, and other derivatives.
Choong, Tung-Chung.
core   +3 more sources