Results 51 to 60 of about 1,329 (197)
European Journal of Sport Science, Volume 25, Issue 5, May 2025.ABSTRACT This study aimed to compare the effects of isocaloric polarized and threshold training intensity distribution on endurance capacity in breast and prostate cancer survivors. A total of 28 breast and 27 prostate cancer survivors were randomly assigned to a polarized (POL, n = 27 (13 women), age 60 ± 8 years, peak oxygen uptake (VO2peak) 23 mL ...
Nikolai Bauer +4 more
wiley +1 more source
Limited matching of the cardiac output response to the peripheral demand of heat stress and exercise
Experimental Physiology, Volume 110, Issue 5, Page 722-734, 1 May 2025.Abstract It is widely accepted that cardiac output matches the prevailing peripheral demand in healthy humans. However, it remains unknown whether stroke volume and heart rate are regulated interdependently to arrive at a specific cardiac output. The aim of this study was to determine whether the healthy human heart responds specifically according to ...
Moritz Lampkemeyer +8 more
wiley +1 more source
Structure and function of serotonin G protein-coupled receptors [PDF]
, 2015 Serotonin receptors are prevalent throughout the nervous system and the periphery, and remain one of the most lucrative and promising drug discovery targets for disorders ranging from migraine headaches to neuropsychiatric disorders such as schizophrenia
McCorvy, John D., Roth, Bryan L.
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Physiological Reports, Volume 13, Issue 9, May 2025.Abstract Decrease in the systemic estradiol (E2) levels caused by menopause has been associated with an increased risk for cardiovascular disease. We have previously shown that E2 level is associated with the systemic response to an acute bout of endurance exercise.
Sira Karvinen +7 more
wiley +1 more source
Analytical and behavioral characterization of 1‐hexanoyl‐LSD (1H‐LSD)
Drug Testing and Analysis, Volume 17, Issue 4, Page 561-569, April 2025.Analytical and pharmacological data were obtained from 1‐hexanoyl‐LSD (1H‐LSD). The mouse head‐twitch response revealed that 1H‐LSD induced LSD‐like effects (ED50 = 387 nmol/kg). The behavioral and analytical characterization of novel lysergamides aim to extend the understanding of structure–activity relationships and disseminate data for those ...
Simon D. Brandt +4 more
wiley +1 more source
Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 2, April 2025.ABSTRACT Background Metabolic syndrome (MetS) is a set of five cardiometabolic risk factors that typically worsen with age. One exercise‐training programme is effective at improving those factors in middle‐aged individuals with MetS. To our knowledge, exercise‐training efficacy as MetS individuals age has not been explored.
Felix Morales‐Palomo +4 more
wiley +1 more source
5-HT2B Receptor-mediated Cardiac Valvulopathy [PDF]
, 2018 5-HT2B receptor agonism causes cardiac valvulopathy, a condition characterized by thickening of the heart valves and as a result, regurgitation of blood within the heart. The anti-obesity drug fenfluramine, which was originally prescribed as an anorectic,
Nistala, Pallavi
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Receptor interaction profiles of novel psychoactive tryptamines compared with classic hallucinogens [PDF]
, 2016 The present study investigated interactions between the novel psychoactive tryptamines DiPT, 4-OH-DiPT, 4-OH-MET, 5-MeO-AMT, and 5-MeO-MiPT at monoamine receptors and transporters compared with the classic hallucinogens lysergic acid diethylamide (LSD ...
Hoener, Marius C. +3 more
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Physiological Reports, Volume 13, Issue 7, April 2025.This graphical abstract illustrates the role of ventilatory efficiency (V'E/V'CO2) in elite athletes, analyzed by sex and sport category. Abstract Ventilatory efficiency during cardiopulmonary exercise testing (CPET) is obtained by relating minute ventilation (V'E) to CO2 output (V'CO2).
Maria Rosaria Squeo +7 more
wiley +1 more source
Effects of alkaloid exposure and environment on digestion, nutrient balance, and immune function in beef cattle [PDF]
Fescue toxicosis is a complex condition in cattle caused by the consumption of ergot alkaloids produced by the endophyte (Epichloe coenophiala) that infects tall fescue [Lolium arundinaceum (Schreb.) Darbysh.].
Zeltwanger, Joshua
core +1 more source