Results 141 to 150 of about 1,657 (154)

Connectivity Map and perturbation-based sensitivity analysis identifies MEK inhibitors as senolytics in human lung fibroblasts

Nayeri Rad A, Sperger S, Marsh LM, Hoetzenecker K, Lämmermann I, Grillari J.   +5 more
europepmc   +1 more source

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Knockdown of ERN1 disturbs the expression of phosphoserine aminotransferase 1 and related genes in glioblastoma cells

Archives of Biochemistry and Biophysics
Endoplasmic reticulum stress and synthesis of serine are essential for tumor growth, but the mechanism of their interaction is not clarified yet. The overarching goal of this work was to investigate the impact of ERN1 (endoplasmic reticulum to nucleus signaling 1) inhibition on the expression of serine synthesis genes in U87MG glioblastoma cells ...
Oleksandr N Minchenko, Dmytro O Minchenko   +1 more
exaly   +3 more sources

Effect of ERN1 knockdown on the expression of MAP3K5, MAP4K3, CIB1, RIPK1, and RIPK2 genes in U87 glioma cells and its hypoxic regulation

Journal of Investigational Biochemistry, 2014
ERN1 (endoplasmic reticulum to nucleus signaling 1)-mediated signaling pathway plays an important role in glioma growth. We studied the possible role of protein kinases MAP4K3, MAP3K5, RIPK1, and RIPK2 as well as protein kinase interacting protein CIB1 in suppression of U87 glioma cell proliferation upon ERN1 knockdown.
Dmytro O Minchenko
exaly   +2 more sources

Inhibition of ERN1 Signaling is Important for the Suppression of Tumor Growth

Clinical Cancer Drugs, 2021
Oleksandr N Minchenko, Dariia O Tsymbal, Dmytro O Minchenko   +2 more
exaly  

Radiation induces EIF2AK3/PERK and ERN1/IRE1 mediated pro-survival autophagy

Autophagy, 2019
Madhuri Chaurasia, Swapnil Gupta, Asmita Das   +2 more
exaly  

Inhibition of kinase and endoribonuclease activity of ERN1/IRE1α affects expression of proliferationrelated genes in U87 glioma cells

Endoplasmic Reticulum Stress in Diseases, 2015
Dariia O Tsymbal
exaly  

ERN1 and CYCLOPS coordinately activate NIN signaling to promote infection thread formation in Lotus japonicus

Journal of Plant Research, 2019
Takashi Soyano, Koji Yano, Makoto Hayashi   +2 more
exaly  

Molecular Mechanisms of ERN1-Mediated Angiogenesis

International Journal of Physiology and Pathophysiology, 2014
Oleksandr N Minchenko, Dmytro O Minchenko   +1 more
exaly  

Fumonisin B1 induces autophagic cell death via activation of ERN1-MAPK8/9/10 pathway in monkey kidney MARC-145 cells

Archives of Toxicology, 2015
Shutao Yin, Hongbo Hu
exaly  

The Ethylene Responsive Factor Required for Nodulation 1 (ERN1) Transcription Factor Is Required for Infection-Thread Formation in Lotus japonicus

Molecular Plant-Microbe Interactions, 2017
Yasuyuki Kawaharada, Euan K James, Simon Kelly   +2 more
exaly