Results 41 to 50 of about 59,745 (265)

New global error bound for extended linear complementarity problems

Journal of Inequalities and Applications, 2018
For the extended linear complementarity problem (ELCP), by virtue of a new residual function, we establish a new type of global error bound under weaker conditions.
Hongchun Sun, Min Sun, Yiju Wang
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Tighter bounds on the Gaussian Q-function based on wild horse optimization algorithm

Journal of Algorithms & Computational Technology
The Gaussian Q-function (GQF) is widely used in various scientific and engineering fields, especially in telecommunications and wireless communication.
Reza Etesami, Mohsen Madadi
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Term Filtering with Bounded Error [PDF]

2010 IEEE International Conference on Data Mining, 2010
In this paper, we consider a novel problem referred to as term filtering with bounded error to reduce the term (feature) space by eliminating terms without (or with bounded) information loss. Different from existing works, the obtained term space provides a complete view of the original term space. More interestingly, several important questions can be
Zi Yang, Wei Li 0044, Jie Tang 0001, Juanzi Li   +3 more
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Error Bounds for Fractional Integral Inequalities with Applications

Fractal and Fractional
Fractional calculus has been a concept used to obtain new variants of some well-known integral inequalities. In this study, our main goal is to establish the new fractional Hermite–Hadamard, and Simpson’s type estimates by employing a differentiable ...
Nouf Abdulrahman Alqahtani, Shahid Qaisar, Arslan Munir, Muhammad Naeem, Hüseyin Budak   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Error Bounds for Lagrange Interpolation

Journal of Approximation Theory, 1995
Consider an interpolation of functions \(f\in W_ \infty^ m [a,b]\) by Lagrange polynomials \(\ell_{m-1}\), \(\Delta(f)\) of degree \(m-1\) at the mesh \(\Delta\) of the interpolating nodes \(\{t_ j\}^ m_ 1\). Error bounds due to this approximation is evaluated as \[ L_{m,k} (\Delta)= \sup_{x\in [a,b]} L_{m,k} (\Delta,x)= {\textstyle {1\over m ...
openaire   +1 more source