Results 41 to 50 of about 82,940 (314)

Two-dimensional patterns with distinct differences; constructions, bounds, and maximal anticodes [PDF]

open access: yes, 2010
A two-dimensional (2-D) grid with dots is called a configuration with distinct differences if any two lines which connect two dots are distinct either in their length or in their slope.
Etzion, T.   +3 more
core   +1 more source

Regularities and their relations to error bounds [PDF]

open access: yesMathematical Programming, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Kung Fu Ng, Wei Hong Yang
openaire   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Quantum metrology with open dynamical systems

open access: yesNew Journal of Physics, 2013
This paper studies quantum limits to dynamical sensors in the presence of decoherence. A modified purification approach is used to obtain tighter quantum detection and estimation error bounds for optical phase sensing and optomechanical force sensing ...
Mankei Tsang
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Error estimation and adaptivity for PGD based on complementary solutions applied to a simple 1D problem

open access: yesAdvanced Modeling and Simulation in Engineering Sciences, 2020
Reduced order methods are powerful tools for the design and analysis of sophisticated systems, reducing computational costs and speeding up the development process.
Jonatha Reis   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

New global error bound for extended linear complementarity problems

open access: yesJournal of Inequalities and Applications, 2018
For the extended linear complementarity problem (ELCP), by virtue of a new residual function, we establish a new type of global error bound under weaker conditions.
Hongchun Sun, Min Sun, Yiju Wang
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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