Results 51 to 60 of about 59,745 (265)

Quantum error detection .II. Bounds [PDF]

IEEE Transactions on Information Theory, 2000
In Part II we show that there exist quantum codes whose probability of undetected error falls exponentially with the length of the code and derive bounds on this exponent.The lower (existence) bound for stabilizer codes is proved by a counting argument for classical self-orthogonal quaternary codes.
Alexei E. Ashikhmin, Alexander Barg, Emanuel Knill, Simon Litsyn   +3 more
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Direct Analysis of Zero-Noise Extrapolation: Polynomial Methods, Error Bounds, and Simultaneous Physical-Algorithmic Error Mitigation [PDF]

Quantum
Zero-noise extrapolation (ZNE) is a widely used quantum error mitigation technique that artificially amplifies circuit noise and then extrapolates the results to the noise-free circuit.
Pegah Mohammadipour, Xiantao Li
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Two New Families of Local Asymptotically Minimax Lower Bounds in Parameter Estimation

Entropy
We propose two families of asymptotically local minimax lower bounds on parameter estimation performance. The first family of bounds applies to any convex, symmetric loss function that depends solely on the difference between the estimate and the true ...
Neri Merhav
doaj   +1 more source

Numerical methods for singularly perturbed elliptic problems containing two perturbation parameters

Mathematical Modelling and Analysis, 2006
A priori parameter explicit bounds on the derivatives of the solution of a two parameter singularly perturbed elliptic problem in two space dimensions are presented. These bounds are used to establish parameter uniform error bounds for a numerical method
E. O'Riordan, M. L. Pickett, G. I. Shishkin   +2 more
doaj   +1 more source

A Computational Method for Subdivision Depth of Ternary Schemes

Mathematics, 2020
Subdivision schemes are extensively used in scientific and practical applications to produce continuous shapes in an iterative way. This paper introduces a framework to compute subdivision depths of ternary schemes.
Faheem Khan, Ghulam Mustafa, Aamir Shahzad, Dumitru Baleanu, Maysaa M. Al-Qurashi   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Optimal Stable Approximation for the Cauchy Problem for Laplace Equation

Advances in Mathematical Physics, 2016
Cauchy problem for Laplace equation in a strip is considered. The optimal error bounds between the exact solution and its regularized approximation are given, which depend on the noise level either in a Hölder continuous way or in a logarithmic ...
Hongfang Li, Feng Zhou
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source