Results 71 to 80 of about 601,840 (265)
Let \(R[f]\) be the remainder of some linear approximation method (e.g. polynomial or spline approximation, numerical integration or differentiation), having estimates of the form \(| R[f ]|\leq \rho_ i\| f^{(i)} \|_{L^ p[a,b]}\), \(i=m,\dots, r\), for some \(m\) and \(r\) with \(0\leq m\leq r-1\). In many cases, \(\rho_ m\) and \(\rho_ r\), are known,
openaire +2 more sources
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Fourier Spectral Methods for Some Linear Stochastic Space-Fractional Partial Differential Equations
Fourier spectral methods for solving some linear stochastic space-fractional partial differential equations perturbed by space-time white noises in the one-dimensional case are introduced and analysed.
Yanmei Liu, Monzorul Khan, Yubin Yan
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Uniform Error Estimates of the Finite Element Method for the Navier-Stokes Equations in R2 with L2 Initial Data. [PDF]
Ren S, Wang K, Feng X.
europepmc +1 more source
On a posteriori error estimates [PDF]
Consider a sequence { x n } n = 0 ∞ \{ {x_n}\} _{n = 0}^\infty in a normed space X converging to some x ∗ ∈ X ...
openaire +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Error estimates and physics informed augmentation of neural networks for thermally coupled incompressible Navier Stokes equations. [PDF]
Goraya S, Sobh N, Masud A.
europepmc +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Uniform Finite Element Error Estimates with Power-Type Asymptotic Constants for Unsteady Navier-Stokes Equations. [PDF]
Xie C, Wang K.
europepmc +1 more source

