Results 71 to 80 of about 2,341,583 (290)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Model error and sequential data assimilation. A deterministic formulation

open access: yes, 2008
Data assimilation schemes are confronted with the presence of model errors arising from the imperfect description of atmospheric dynamics. These errors are usually modeled on the basis of simple assumptions such as bias, white noise, first order Markov ...
Carrassi, A., Nicolis, C., Vannitsem, S.
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Feedforward pilot-aided carrier synchronization using a DCT basis expansion [PDF]

open access: yes, 2009
This contribution deals with phase noise estimation from pilot symbols. The phase noise process is approximated by an expansion of Discrete Cosine-Transform (DCT) basis functions containing only a few terms.
Bhatti, Jabran, Moeneclaey, Marc
core  

Self-equilibrated residual based error estimation on 1-irregular meshes in finite elasticity

open access: yesArchives of Mechanics
We consider well-established techniques for the residual error estimation of finite element approximations applied to problems in finite elasticity.
W. Rachowicz, A. Zdunek
doaj   +1 more source

Lower bounds for the low-rank matrix approximation

open access: yesJournal of Inequalities and Applications, 2017
Low-rank matrix recovery is an active topic drawing the attention of many researchers. It addresses the problem of approximating the observed data matrix by an unknown low-rank matrix. Suppose that A is a low-rank matrix approximation of D, where D and A
Jicheng Li, Zisheng Liu, Guo Li
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Mean Estimation from Adaptive One-bit Measurements

open access: yes, 2017
We consider the problem of estimating the mean of a normal distribution under the following constraint: the estimator can access only a single bit from each sample from this distribution.
Duchi, John C., Kipnis, Alon
core   +1 more source

A Viscous Boundary Layer Mesh Adaptation Method and Its Application in High-Angle-of-Attack Separated Flows

open access: yesApplied Sciences
Adjoint-based mesh adaptation method serves as an effective approach to improve the predictive accuracy of aerodynamic characteristics. However, viscous boundary layer grids often encounter issues such as hanging nodes, negative volumes, and directional ...
Pengcheng Cui   +8 more
doaj   +1 more source

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