Results 71 to 80 of about 1,666,189 (240)

CO on Pt(111) puzzle; A possible solution

, 2001
CO adsorption on the Pt(111) surface is studied using first-principles methods. As found in a recent study [Feibelman, et al., J. Phys. Chem. B 105, 4018 (2001)], we find the preferred adsorption site within density functional theory to be the hollow ...
Grinberg, Ilya, Rappe, Andrew M., Yourdshahyan, Yashar   +2 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

The numerical solution of an Abel integral equation by the optimal quadrature formula

Results in Applied Mathematics
In this study, a novel and efficient approach utilizing optimal quadrature formulas is introduced to derive approximate solutions for generalizing Abel’s integral equations. The method, characterized by high accuracy and simplicity, involves constructing
Abdullo Hayotov, Samandar Babaev, Bobomurod Boytillayev   +2 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Estimation for Partial Functional Multiplicative Regression Model

Mathematics
Functional data such as curves, shapes, and manifolds have become more and more common with modern technological advancements. The multiplicative regression model is well suited for analyzing data with positive responses.
Xiaojing Liu, Ping Yu, Jianhong Shi
doaj   +1 more source

Measuring error rates in genomic perturbation screens: gold standards for human functional genomics

Molecular Systems Biology, 2014
Technological advancement has opened the door to systematic genetics in mammalian cells. Genome‐scale loss‐of‐function screens can assay fitness defects induced by partial gene knockdown, using RNA interference, or complete gene knockout, using new ...
Traver Hart, Kevin R Brown, Fabrice Sircoulomb, Robert Rottapel, Jason Moffat   +4 more
doaj   +1 more source

Post-error adjustments

Frontiers in Psychology, 2011
When our brain detects an error, this process changes how we react on ensuing trials. People show post-error adaptations, potentially to improve their performance in the near future.
Claudia eDanielmeier, Markus eUllsperger, Markus eUllsperger   +2 more
doaj   +1 more source

Cubature error bounds for analytic functions [PDF]

Mathematics of Computation, 1973
In this paper, two-dimensional cubature error bounds are developed. It is assumed that the function to be integrated is analytic, and that the domain of integration is contained in [ − 1 , 1 ] × [ − 1 , 1 ] [ - 1,1] \times [ - 1,1] .
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Performance of concatenated Reed-Solomon/Viterbi channel coding [PDF]

The concatenated Reed-Solomon (RS)/Viterbi coding system is reviewed. The performance of the system is analyzed and results are derived with a new simple approach. A functional model for the input RS symbol error probability is presented.
Divsalar, D., Yuen, J. H.
core   +1 more source