Results 121 to 130 of about 7,716 (265)

[Artificial intelligence and disinformation in health: The need for re-education from primary care]. [PDF]

Aten Primaria
Coronado-Vázquez V, Allande-Cussó R, Caparrós-González RA, Gómez-Salgado J.   +3 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

[Students' Perception of Simulator Use in Clinical Dental Practice at Peruvian Universities]. [PDF]

Rev Cient Odontol (Lima)
Mezarina-Mendoza JPI, Garavito-Chang EL, Chávez-Sánchez E, Ramírez-Chaupis MG, Gálvez Ramírez CM, Castañeda-Sarmiento S.   +5 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

[Comprehensive Analysis of Compounded Prescription Orders: Types of Errors and Variability Among Autonomous Communities in Spain]. [PDF]

Farm Comunitarios
Espáriz de la Cruz P.
europepmc   +1 more source

Assessment of forced spirometry quality in healthy adults at 2,700 meters above sea level [PDF]

Biomedica
Valero-Ortiz AS, Wilches-Wilches MR, Roa-Cubaque MA, Palencia-Mojica CL, Umbacía-Salas FÁ, Polanía-Robayo AY, Quemba-Mesa MP, Delgado-Villalba P, Flechas-Robles ÁM.   +8 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

[On the Basis of a Case: Follow-Up of a Patient with Chronic Obstructive Pulmonary Disease (COPD) through the EPOCA Service]. [PDF]

Farm Comunitarios
Deleito Molina O.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

[Chronic pain and persistent pain: A reflection from community-based practice]. [PDF]

Aten Primaria
Alcántara Montero A.
europepmc   +1 more source